آخرین یافته‌های کروناویروس: پاتوژنز و درمان آن

نوع مقاله : مقاله مروری

نویسندگان

1 استادیار، بخش واکسن‌های ویروسی انسانی، مؤسسه‌ی سرم و واکسن‌سازی رازی کرج، کرج، ایران

2 گروه ایمنی‌شناسی، دانشکده‌ی پزشکی، دانشگاه علوم پزشکی اصفهان، اصفهان، ایران

3 دانشیار، گروه ایمنی‌شناسی، دانشکده‌ی پزشکی و مرکز تحقیقات فیزیولوژی، دانشگاه علوم پزشکی اصفهان، اصفهان، ایران

چکیده

بیماری ویروس کرونا (Coronavirus diseases-2019 یا COVID-19) یک نوع پنومونی حاد ویروسی است که با شیوع ناگهانی ازشهر ووهان چین شروع شده است. این بیماری، اگر چه شباهت زیادی با سندرم شدید حاد تنفسی (Severe acute respiratory syndrome یا SARS) و سندرم تنفسی خاور میانه (Middle East respiratory syndrome یا MERS) دارد، اما سرعت سرایت بیش از حد این بیماری، آن را از سایر بیماری‌های پنومونی ویروسی متمایز کرده است. عوارض ریوی و عفونت‌های ناشی از این ویروس و نبود درمان‌های اختصاصی، توانسته است یکی از بغرنج‌ترین همه‌گیری‌های قرن اخیر را به وجود آورد. در این مقاله‌ی مروری سعی شده است که آخرین یافته‌های ایمنوپاتوژنز و درمان‌های کاربردی و جدید ویروس کرونا به بحث و تبادل نظر گذاشته شود.

کلیدواژه‌ها

عنوان مقاله [English]

Recent Findings of Coronavirus: The Pathogenesis and Treatment

نویسندگان [English]

  • Reza Bastan 1
  • Neda Kasiri 2
  • Nahid Eskandari 3
1 Assistant Professor, Department of Human Vaccines, Razi Serum and Vaccine Research Institute, Karaj, Iran
2 Department of Immunology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
3 Associate Professor, Department of Immunology, School of Medicine AND Applied Physiology Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
چکیده [English]

Coronavirus disease-2019 (COVID-19) is a type of acute viral pneumonia, which began with a sudden outbreak in Wuhan, China. Although closely related to severe acute respiratory syndrome, severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS), the disease excessive transmission rate distinguishes it from other viral pneumonia diseases. The pulmonary complications and infections caused by this virus, as well as the lack of specific therapeutic have caused one of the most complicated epidemics of the last century. In this review article, we attempted to discuss and describe the latest findings of immunopathogenesis, as well new and applicable treatments for coronavirus disease.

کلیدواژه‌ها [English]

  • Coronavirus infections
  • Pneumonia
  • MERS virus
  • SARS virus

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مجله دانشکده پزشکی اصفهان
دوره 38، شماره 567 - شماره پیاپی 567
فروردین و اردیبهشت 1399
صفحه 154-164

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سابقه مقاله

  • تاریخ دریافت: 11 فروردین 1399
  • تاریخ بازنگری: 11 آبان 1403
  • تاریخ پذیرش: 17 فروردین 1401

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