دوره 29، شماره 154: هفته دوم آبان ماه 1390:1326-1333

ارزیابی و مقایسه‌ی آثار و هزینه‌های آزمون‌های غیر تهاجمی تشخیص میکروب هلیکوباکتر پیلوری

شادی کاظمی, حامد دقاق‌زاده, یلدا کاظمی, محمدرضا حبیب‌زاده, فیروزه معین‌زاده, مجید داوری, حمید توکلی, محمد حسن امامی

چکیده


مقدمه: هلیکوباکتر پیلوری شایع‌ترین میکروب کلونیزه کننده‌ی دستگاه گوارش است. جهت اثبات عفونت از روش‌های مختلفی نظیر سرولوژی، آزمایش آنتی‌ژنی مدفوعی و آزمایش تنفسی اوره استفاده می‌شود. هدف از این مطالعه، بررسی و مقایسه‌ی آثار و هزینه‌های آزمایش‌های تشخیصی فوق بود.

روش‌ها: 94 بیمار زن و مرد بالغ که اندیکاسیون انجام اندوسکوپی داشتند، وارد مطالعه شدند. در صورتی که نتیجه‌ی حداقل دو آزمایش تشخیصی بیمار (بافت شناسی، آزمایش سریع اوره‌آز، آزمایش آنتی‌ژن مدفوعی یا آزمایش تنفسی اوره) مثبت بود، وی از نظر عفونت با هلیکوباکتر پیلوری مثبت در نظر گرفته شد.

یافته‌ها: دقت آزمایش آنتی‌ژن مدفوعی 91 درصد، آزمایش تنفسی اوره 82 درصد و سرولوژی 52 درصد بود.

نتیجه‌گیری: به دلیل هزینه‌ی کمتر و دقت بالاتر، آزمایش آنتی‌ژن مدفوعی آزمایش ارجح در تشخیص عفونت با میکروب هلیکوباکتر پیلوری، قبل از درمان می‌باشد.


واژگان کلیدی


هليکوباکتر پيلوري؛ آزمایش آنتي‌ژن مدفوعي؛ آزمایش تنفسي اوره

تمام متن:

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مراجع


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