Determining Guidelines for Local Ambulatory Care During Flare-Ups of Mild to Moderate Ulcerative Colitis for Effective Control of the Disease at Home

Document Type : Original Article(s)

Authors

1 Assistant Professor of Gastroenterology and Hepatology, Department of Internal Medicine, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

2 Department of Internal Medicine, School of Medicine, Integrative Functional Gastroenterology Research, Al-Zahra Hospital, Isfahan University of Medical Sciences, Isfahan, Iran

3 Assistant Professor of Gastroenterology and Hepatology, Department of Internal Medicine, School of Medicine, Integrative Functional Gastroenterology Research Al-Zahra Hospital, Isfahan University of Medical Sciences, Isfahan, Iran

4 Department of Pharmacology, School of pharmacy, Isfahan University of Medical Sciences, Isfahan, Iran

5 Professor of Gastroenterology and Hepatology, Department of Internal Medicine, School of Medicine, Integrative Functional Gastroenterology Research, Al-Zahra Hospital, Isfahan University of Medical Sciences, Isfahan, Iran

Abstract

Background: Conventionally, the treatment of ulcerative colitis flares is done on an inpatient basis due to the need for treatment with injectable drugs, but mini flare-ups treatment is generally non-injectable, and mini flare-ups of ulcerative colitis can potentially be managed on an outpatient basis and at home. Given the lack of localized clinical guidelines for managing ulcerative colitis mini flares, this study collected and synthesized expert opinions on treating mini flare-ups in outpatients and at home.
Methods: In this study, the opinions of Iranian experts were examined using a questionnaire and their opinions were summarized. The findings of the studies and the compilation of experts' opinions were used to design an outpatient care guideline for the treatment of ulcerative colitis mini-flares.
Findings: Self-care training and the level of awareness of patients are effective in controlling mini flare-ups, and the use of 5-ASA and oral and rectal corticosteroids is recommended in the treatment of mini flare-ups. Also, modifying the diet in patients was considered beneficial. In this study, the administration of probiotics and biomolecular drugs on an outpatient basis in mini flare-ups was not recommended.
Conclusion: Based on the findings of this study, the mini flare-ups treatment was recommended on an outpatient basis and at home. This recommendation requires consideration of the patient's access to medical centers and the awareness levels of both the patient and caregivers.

Highlights

Hadi Abdolahi: Google Scholar 

Mohammad Jafari: Google Scholar

Peyman Adibi: Google Scholar

Keywords

Main Subjects

References

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Journal of Isfahan Medical School
Volume 43, Issue 812
4th Week, June
May and June 2025
Pages 393-400

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History

  • Receive Date: 20 October 2024
  • Accept Date: 01 July 2025

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