نوع مقاله : Original Article(s)
نویسندگان
1 استاد، گروه پاتولوژی، دانشکدهی پزشکی، مرکز تحقیقات بیماریهای عفونی و گرمسیری، دانشگاه علوم پزشکی اصفهان، اصفهان، ایران
2 دانشکدهی پزشکی، دانشگاه علوم پزشکی اصفهان، اصفهان، ایران
چکیده
تازه های تحقیق
آذر برادران: Google Scholar
کلیدواژهها
موضوعات
عنوان مقاله [English]
نویسندگان [English]
Background: Soft tissue sarcomas (STSs) are rare neoplasms that account for approximately 1 to 2 % of all adult malignancies. In this regard, this study aimed to assess the frequency distribution of risk factors in various types of STSs.
Methods: This descriptive-analytical study was conducted on medical reports of 100 patients with a definitive diagnosis of STS in the pathology department of Al-Zahra Hospital. Data, including age, gender, previous history of radiotherapy, previous history of receiving high-dose radiation during cancer treatment, disease recurrence, family history in first-degree relatives, exposure to chemical compounds, primary site, and STS type, were extracted from medical records and interviews. The Chi-square test was used for data analysis.
Findings: Among 100 patients, 46 were men and 54 were women. The most common STS types in men and women were myxoid liposarcoma and leiomyosarcoma, with frequencies of 9 and 8, respectively. The most frequent STS type and primary site were liposarcoma (n = 16) and the retroperitoneum (n = 24), respectively. High-grade STSs were observed in 64% of patients. No significant difference was found among STSs regarding gender, history of radiotherapy, genetic disease, immunodeficiency disease, exposure to chemical compounds, or trauma (P > 0.05). A significant difference was observed among the different types of STSs regarding age, primary site, tumor grade, and disease recurrence (P < 0.05).
Conclusion: According to these findings, liposarcoma was the most common STS type. In addition, the different types of STSs were influenced by age and involved specific primary sites. Furthermore, the STS type may affect tumor grade and recurrence. However, the types of soft tissue sarcomas do not appear to be associated with gender, history of radiotherapy, genetic disease, immunodeficiency disease, exposure to chemical compounds, or trauma.
کلیدواژهها [English]
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