Prevalence of Vitamin D Deficiency and its Correlation with Mortality in Pediatric Intensive Care Unit

Document Type : Original Article (s)

Authors

1 Assistant Professor, Department of Anesthesiology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

2 Student of Medicine, Student Research Committee, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

Abstract

Background: Vitamin D deficiency is common in pediatric intensive care unit (PICU) and is related with mortality. The aim of current study was evaluation of prevalence and correlation between vitamin D deficiency and mortality in pediatric intensive care unit.Methods: In this cross-sectional study, 61 pediatrics patients admitted to pediatric intensive care unit were enrolled according to inclusion and exclusion criteria. Serum levels of vitamin D were measured in the patients at onset of study; then, patients were allocated into two groups of vitamin D deficiency (less than 20 ng/ml) and normal (vitamin D of more than 20 ng/ml). Mortality rate was evaluated in patients according to pediatric risk of mortality III (PRISM III) and pediatric index of mortality 2 (PIM 2).Findings: Both the indexes (PIM 2 and PRISM III) were higher in vitamin D deficiency group (P = 0.020 and P < 0.0001, respectively). There was no significant correlation between serum level of vitamin D with PIM 2 (P = 0.590) and PRISM III (P = 0.180).Conclusion: According to our results, the prevalence of mortality was higher in vitamin D deficiency group compared to normal group; but there was no significant correlation between serum levels of vitamin D and mortality rate.

Keywords

References

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Journal of Isfahan Medical School
Volume 35, Issue 456 - Serial Number 456
September and October 2018
Pages 1654-1659

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History

  • Receive Date: 02 September 2017
  • Revise Date: 07 June 2024
  • Accept Date: 06 April 2022

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