Diagnosis of Vulvovaginal Candidiasis via Automatic Extraction of Candida Fungus from Pap Smear Images

Document Type : Original Article (s)

Authors

1 MSc Student, Department of Bioelectric and Biomedical Engineering, School of Advanced Medical Technology AND Student Research Committee, Isfahan University of Medical Sciences, Isfahan, Iran

2 Associate Professor, Department of Pathology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

3 Associate Professor, Department of Bioelectric and Biomedical Engineering, School of Advanced Medical Technology, Isfahan University of Medical Sciences, Isfahan, Iran

Abstract

Background: Vulvovaginal candidiasis (VVC) is a common clinical problem due to occurrence overgrowth of candida in genital system mucosa of females. The aim of this study was automatic diagnosis of vulvovaginal candidiasis via detection and extraction of candida fungus from microscopic images of Pap smear samples. We used image processing techniques to detect candida fungus.Methods: The sample space consisted of 200 microscopic images. Microscopic images were prepared from 49 Pap smear samples using Nikon1 V1 camera mounted on Nikon Eclipse 50i light microscope. For uniform illumination of the images, bottom-hat filtering was used. De-correlation stretching and linear contrast stretching were used for contrast enhancement. Different geometric features such as area, major axis, minor axis, eccentricity, perimeter, compactness, and decision tree classifier were used for extraction of mycelium and conidium of candida.Findings: The results of extraction of mycelium showed a specificity of 98.64% and a sensitivity of 96.88%. The corresponding values for conidium detection were 91.54% and 92.32%, respectively.Conclusion: According to our findings, this software would be helpful to pathologists in the diagnosis of vulvovaginal candidiasis in prevention of eyestrain. It could increase the accuracy of diagnosis, too.

Keywords

References

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Journal of Isfahan Medical School
Volume 32, Issue 304 - Serial Number 304
September and October 2014
Pages 1659-1667

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History

  • Receive Date: 16 September 2014
  • Revise Date: 20 May 2024
  • Accept Date: 06 April 2022

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