تاثیر تمرین تناوبی شدید کم‌حجم نظارت‌شده و نظارت‌نشده بر برخی شاخص‌های متابولیک و آتروژنیک در مردان مبتلا به دیابت نوع دو

نوع مقاله : Original Article(s)

نویسندگان

1 استادیار، گروه تربیت بدنی و علوم ورزشی، دانشکده ادبیات و علوم انسانی، دانشگاه نیشابور، نیشابور، ایران

2 دانشیار، گروه فیزیولوژی ورزشی و حرکات اصلاحی، دانشکده علوم ورزشی، دانشگاه ارومیه، ارومیه، ایران

3 استادیار، گروه علوم ورزشی، دانشکده ادبیات و علوم انسانی، دانشگاه زابل، زابل، ایران

4 دکتری فیزیولوژی ورزشی، گروه تربیت بدنی، مرکز آموزش علمی کاربردی سبزوار 2 ، سبزوار، ایران

10.48305/jims.v43.i820.0712

چکیده

مقاله پژوهشی




مقدمه: فعالیت بدنی و تمرینات ورزشی به عنوان بخشی جدایی‌ناپذیر از مدیریت و کنترل متابولیک و عوامل قلبی- ‌عروقی در دیابت نوع دو شناخته می‌شود. هدف از مطالعه‌ی حاضر، مقایسه‌ی تأثیر تمرین تناوبی شدید کم‌حجم نظارت‌شده و نظارت‌نشده بر برخی شاخص‌های متابولیک و آتروژنیک در مردان مبتلا به دیابت نوع دو بود.
روش‌ها: در این مطالعه‌ی نیمه‌تجربی، 30 مرد مبتلا به دیابت نوع دو به صورت تصادفی در سه گروه مساوی (10 نفر) تمرین تناوبی شدید کم‌حجم نظارت‌شده، تمرین تناوبی شدید کم‌حجم نظارت‌نشده و کنترل تقسیم شدند. آزمودنی‌های گروه‌‌های تجربی سه جلسه در هفته به مدت هشت هفته به اجرای تمرینات تناوبی شدید کم حجم پرداختند. قبل و پس از مداخله، جهت اندازه‌گیری گلوکز ناشتا، پروفایل لیپیدی به منظور محاسبه‌ی شاخص آتروژنیک پلاسما، شاخص خطر کاستلی و ضریب آتروژنیک از آزمودنی‌ها نمونه‌های خونی به عمل آمد. از آزمون تحلیل کواریانس، آزمون تعقیبی LSD و سطح معنی‌داری 05/0 P < جهت تجزیه و تحلیل داده‌ها استفاده شد.
یافته‌ها: بعد از هشت هفته، توده‌ی چربی بدن (0/01 = P)، گلوکز ناشتا (0/01 = P)، کلسترول تام (0/01 = P)، تری‌گلیسرید (0/01 = P) و شاخص آتروژنیک پلاسما (0/01 = P) در گروه تمرین تناوبی شدید کم‌حجم نظارت‌شده در مقایسه با گروه کنترل به طور معنی‌داری کاهش یافت. تغییر معنی‌داری در وزن بدن (0/08 = P)، شاخص توده‌ی ‌بدنی (0/06 = P)، شاخص خطر کاستلی (0/08 = P)، ضریب آتروژنیک (0/08 = P)، کلسترول لیپوپروتئین با چگالی کم (0/71 = P) و کلسترول لیپوپروتئین با چگالی بالا (0/22 = P) بین گروه‌ها مشاهده نشد.
نتیجه‌گیری: مطالعه‌ی حاضر نشان داد که تمرین تناوبی شدید کم‌حجم بصورت نظارت‌شده می‌تواند با صرفه‌جویی در مدت زمان تمرین منجر بهبود معنادار شاخص‌های متابولیکی و قلبی‌عروقی در بیماران مبتلا به دیابت نوع دو گردد. اما این میزان بهبود در تمرینات نظارت‌نشده مشاهده نمی‌شود.

تازه های تحقیق

مهدی زارعی: PubMed ,Google Scholar

کاظم خدایی: Google Scholar

جواد نخزری خداخیر: Google Scholar

کلیدواژه‌ها

موضوعات

عنوان مقاله [English]

The Effect of Supervised and Unsupervised Low-Intensity Interval Training on Some Metabolic and Atherogenic Indices in Men with Type 2 Diabetes

نویسندگان [English]

  • Mehdi Zarei 1
  • Kazem Khodaei 2
  • Javad Nakhzari Khodakheir 3
  • Arash Mohammadi 4
1 Assistant Professor, Department of Physical Education and Sport Sciences, Faculty of Literature and Humanities, University of Neyshabur, Neyshabur, Iran
2 Assistant Professor, Department of Sports Physiology and Corrective Movements, Faculty of Sports Sciences, Urmia University, Urmia- Iran
3 Assistant professor, Department of physical education and Sport Sciences, school of Human Sciences, University of Zabol, Zabol, Iran
4 Department of Physical education and Sport Sciences, Applied Scientific Education Center of Sabzevar2, Sabzevar, Iran
چکیده [English]

Background: Physical activity and exercise training are recognized as an integral part of the management and control of metabolic and cardiovascular factors in type 2 diabetes. The aim of the present study was to compare the effects of supervised and unsupervised low-volume high-intensity interval training on some metabolic indices, cardiovascular risk factors, and atherogenic indices in men with type 2 diabetes.
Methods: In this semi-experimental study, 30 men with type 2 diabetes were randomly divided into three equal groups (n =10 each): supervised low-volume high-intensity interval training, unsupervised low-volume high-intensity interval training, and control. The subjects in the experimental groups performed high-intensity interval training three sessions per week for eight weeks. Before and after the intervention, blood samples were taken from the subjects to measure fasting glucose, lipid profile to calculate the atherogenic index of plasma, Castelli risk index, and atherogenic coefficient. Analysis of covariance, LSD post hoc test, and a significance level of P < 0.05 were used for data analysis.
Findings: After eight weeks, body fat mass (P = 0.01), fasting glucose (P = 0.00), total cholesterol (P = 0.01), triglycerides (P = 0.01), and the atherogenic index of plasma (P = 0.01) were significantly reduced in the supervised low-intensity interval training group compared with the control group. No significant changes were observed in body weight (P = 0.08), body mass index (P = 0.06), Castelli risk index (P = 0.08), atherogenic index (P = 0.08), low-density lipoprotein cholesterol (P = 0.71), and high-density lipoprotein cholesterol (P = 0.22) between the groups.
Conclusion: The present study showed that supervised low-volume high-intensity interval training can lead to significant improvement in metabolic and cardiovascular indices in patients with type 2 diabetes by saving training time. However, this level of improvement was not observed with unsupervised training.

کلیدواژه‌ها [English]

  • High-intensity interval training
  • Lipids
  • Diabetes mellitus
  • Type 2

مراجع

  1. Roden M, Shulman GI. The integrative biology of type 2 diabetes. Nature 2019; 576(7785): 51-60.
  2. Galicia-Garcia U, Benito-Vicente A, Jebari S, Larrea-Sebal A, Siddiqi H, Uribe KB, et al. Pathophysiology of type 2 diabetes mellitus. Int J Mol Sci 2020; 21(17): 6275.
  3. Chatterjee S, Khunti K, Davies MJ. Type 2 diabetes. Lancet 2017; 389(10085): 2239-51.
  4. Zhu W, Sahar NE, Javaid HMA, Pak ES, Liang G, Wang Y, et al. Exercise-induced irisin decreases inflammation and improves NAFLD by competitive binding with MD2. Cells 2021; 10(12): 3306.
  5. Umpierre D, Ribeiro PAB, Schaan BD, Ribeiro JP. Volume of supervised exercise training impacts glycaemic control in patients with type 2 diabetes: a systematic review with meta-regression Diabetologia 2013; 56(2): 242-51.
  6. Way KL, Hackett DA, Baker MK, Johnson NA. The effect of regular exercise on insulin sensitivity in type 2 diabetes mellitus: a systematic review and meta-analysis. Diabetes Metab J 2016; 40(4): 253-71.
  7. Colberg SR, Sigal RJ, Yardley JE, Riddell MC, Dunstan DW, Dempsey PC, et al. Physical activity/exercise and diabetes: a position statement of the American Diabetes Association. Diabetes Care 2016; 39(11): 2065-79.
  8. Weston KS, Wisløff U, Coombes JS. High-intensity interval training in patients with lifestyle-induced cardiometabolic disease: a systematic review and meta-analysis. Br J Sports Med 2014; 48(16): 1227-34.
  9. Sabag A, Little JP, Johnson NA. Low‐volume high‐intensity interval training for cardiometabolic health. J Physiol 2022; 600(5): 1013-26.
  10. Way KL, Sabag A, Sultana RN, Baker MK, Keating SE, Lanting S, et al. The effect of low-volume high-intensity interval training on cardiovascular health outcomes in type 2 diabetes: A randomised controlled trial. Int J Cardiol 2020; 320: 148-54.
  11. Gajanand T, Keating SE, Brown WJ, Hordern MD, Fassett RG, Coombes JS. Comparing the efficacy of supervised and unsupervised exercise training on glycaemic control in type 2 diabetes: a systematic review. Curr Diabetes Rev 2020; 16(6): 570-9.
  12. Hayashino Y, Jackson JL, Fukumori N, Nakamura F, Fukuhara S. Effects of supervised exercise on lipid profiles and blood pressure control in people with type 2 diabetes mellitus: a meta-analysis of randomized controlled trials. Diabetes Res Clin Pract 2012; 98(3): 349-60.
  13. Oliveira C, Simões M, Carvalho J, Ribeiro J. Combined exercise for people with type 2 diabetes mellitus: a systematic review. Diabetes Res Clin Pract 2012; 98(2): 187-98.
  14. Umpierre D, Ribeiro PA, Kramer CK, Leitao CB, Zucatti AT, Azevedo MJ, et al. Physical activity advice only or structured exercise training and association with HbA1c levels in type 2 diabetes: a systematic review and meta-analysis. JAMA 2011; 305(17): 1790-9.
  15. Little JP, Gillen JB, Percival ME, Safdar A, Tarnopolsky MA, Punthakee Z, et al. Low-volume high-intensity interval training reduces hyperglycemia and increases muscle mitochondrial capacity in patients with type 2 diabetes. J Appl Physiol (1985) 2011; 111(6): 1554-60.
  16. Ahmad AM, Mahmoud AM, Serry ZH, Mohamed MM, Abd Elghaffar HA. Effects of low-versus high-volume high-intensity interval training on glycemic control and quality of life in obese women with type 2 diabetes. A randomized controlled trial. J Exerc Sci Fit 2023; 21(4): 395-404.
  17. Winding KM, Munch GW, Iepsen UW, Van Hall G, Pedersen BK, Mortensen SP. The effect on glycaemic control of low‐volume high‐intensity interval training versus endurance training in individuals with type 2 diabetes. Diabetes Obes Metab 2018; 20(5): 1131-9.
  18. Poon ET-C, Little JP, Sit CH-P, Wong SH-S. The effect of low-volume high-intensity interval training on cardiometabolic health and psychological responses in overweight/obese middle-aged men. J Sports Sci 2020; 38(17): 1997-2004.
  19. Marcotte-Chénard A, Tremblay D, Mony M-M, Boulay P, Brochu M, Morais JA, et al. Acute and chronic effects of low-volume high-intensity interval training compared to moderate-intensity continuous training on glycemic control and body composition in older women with type 2 diabetes. Obesities 2021; 1(2): 72-87.
  20. Karstoft K, Winding K, Knudsen SH, Nielsen JS, Thomsen C, Pedersen BK, et al. The effects of free-living interval-walking training on glycemic control, body composition, and physical fitness in type 2 diabetic patients: a randomized, controlled trial. Diabetes Care 2013; 36(2): 228-36.
  21. Mitranun W, Deerochanawong C, Tanaka H, Suksom D. Continuous vs interval training on glycemic control and macro‐and microvascular reactivity in type 2 diabetic patients. Scand J Med Sci Sports 2014; 24(2): e69-e76.
  22. Terada T, Friesen A, Chahal BS, Bell GJ, McCargar LJ, Boulé NG. Feasibility and preliminary efficacy of high intensity interval training in type 2 diabetes. Diabetes Res Clin Pract 2013; 99(2): 120-9.
  23. Alvarez C, Ramirez-Campillo R, Martinez-Salazar C, Mancilla R, Flores-Opazo M, Cano-Montoya J, et al. Low-volume high-intensity interval training as a therapy for type 2 diabetes. Int J Sports Med 2016; 37(09): 723-9.
  24. Shahiddoust F, Monazzami AA. Exercise-induced changes in insulin sensitivity, atherogenic index of plasma, and CTRP1/CTRP3 levels: the role of combined and high-intensity interval training in overweight and obese women. BMC Sports Sci Med Rehabil 2025; 17(1): 73.
  25. Mohammadi S, Monazzami A, Alavimilani S. Effects of eight-week high-intensity interval training on some metabolic, hormonal and cardiovascular indices in women with PCOS: a randomized controlled trail. BMC Sports Sci Med Rehabil 2023; 15(1): 47.
  26. Fennell C, Peroutky K, Glickman E. Effects of supervised training compared to unsupervised training on physical activity, muscular endurance, and cardiovascular parameters. MOJ Orthop Rheumatol 2016; 5(4): 00184.
  27. Costa SN, Boiko Ferreira LH, Barauce Bento PC. The effects of supervision on three different exercises modalities (supervised vs. home vs. supervised+ home) in older adults: Randomized controlled trial protocol. PLoS One 2021; 16(11): e0259827.
  28. Cassidy S, Vaidya V, Houghton D, Zalewski P, Seferovic JP, Hallsworth K, et al. Unsupervised high-intensity interval training improves glycaemic control but not cardiovascular autonomic function in type 2 diabetes patients: A randomised controlled trial. Diab Vasc Dis Res 2019; 16(1): 69-76
  29. Alam S, Stolinski M, Pentecost C, Boroujerdi MA, Jones RH, Sonksen PH, et al. The effect of a six-month exercise program on very low-density lipoprotein apolipoprotein B secretion in type 2 diabetes. J Clin Endocrinol Metab 2004; 89(2): 688-94.
مجله دانشکده پزشکی اصفهان
دوره 43، شماره 820
هفته 4، مرداد
مرداد و شهریور 1404
صفحه 712-721

فایل ها

سابقه مقاله

  • تاریخ دریافت: 30 فروردین 1404
  • تاریخ پذیرش: 31 شهریور 1404

هم رسانی

ارجاع به این مقاله

آمار