Study of Type and Antimicrobial Resistance in Sternal Wound Infection Following Coronary Artery Bypass Graft Surgery

Document Type : Original Article (s)

Authors

1 Assistant Professor, Department of Microbiology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

2 Student of Medicine, School of Medicine AND Student Research Committee, Isfahan University of Medical Sciences, Isfahan, Iran

3 Assistant Professor, Nosocomial Infection Research Center AND Department of Microbiology, Isfahan University of Medical Sciences, Isfahan, Iran

4 Lecturer, Department of Microbiology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

5 MSc Student, Department of Microbiology, School of Medicine AND Student Research Committee, Isfahan University of Medical Sciences, Isfahan, Iran

Abstract

Background: Sternal ulcer infections have a great importance and complexity following coronary artery bypass graft (CABG) surgery. Although this kind of infection has a low prevalence but the complications are severe. The purpose of this study was to determine the type of microorganism and antibacterial resistance in sternal wound infections following CABG surgery in Shahid Chamran hospital in Isfahan, Iran, from 2009 to 2012.Methods: In this descriptive and analytical study, 275 cases of CABG operation were entered. Sternal wound secretion samples of suspected patients were cultured and the type of the causative bacteria were determined. Also, antibiogram test was done on the grown strains and antibacterial resistance patterns were determined.Findings: Of 275 CABG surgeries, 13 cultured sternal wound samples showed positive bacterial colonization. The types of bacterial samples were Staphylococcus epidermidis, Klebsiella, Escherichia coli and Pseudomonas in four, four, three and two cases, respectively. The mean age of patients with and without sternal ulcer infection had no specific differences (P = 0.43). The differences of sex distribution between the case and control group was not statistically significant (P = 0.31), but having diabetes was significantly different between the groups (P < 0.01). Aortic clamping time and body mass index (BMI) showed no significant differences between the groups (P > 0.05).Conclusion: The incidence of sternal infection in patients undergone CABG surgery in this study was moderate compared to other studies; this is influenced by several factors including host, staff relating, environmental and medical equipments factors. Therefore, it is necessary to implement preventive measures at the time of hospitalization and provide appropriate educational programs and preventive methods for staff, patients and their families.

Keywords

References

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Journal of Isfahan Medical School
Volume 31, Issue 241 - Serial Number 241
May and June 2013
Pages 885-893

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History

  • Receive Date: 23 June 2013
  • Revise Date: 26 May 2024
  • Accept Date: 06 April 2022

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