نوع مقاله : مقاله مروری
نویسندگان
1 استادیار، گروه مدیریت خدمات بهداشتی و درمانی، دانشکدهی مدیریت و اطلاعرسانی پزشکی، دانشگاه علوم پزشکی تهران، تهران، ایران
2 استادیار، گروه مدیریت و اقتصاد سلامت و مرکز بهره برداری از دانش سلامت، دانشگاه علوم پزشکی تهران، تهران، ایران
3 عضو هیأت علمی، دانشکدهی پزشکی شانتا او، چین
4 کارشناس ارشد، ادارهی ارزیابی فناوریهای سلامت، معاونت درمان وزارت بهداشت درمان و آموزش پزشکی، تهران، ایران
چکیده
کلیدواژهها
عنوان مقاله [English]
نویسندگان [English]
Background: Positron emission tomography (PET) scan is a non-invasive, complicated and expensive medical imaging technology used for diagnosis and treatment of various diseases including cancers. This study aimed to evaluate the safety and effectiveness of this technology.Methods: The major medical electronic databases including Cochrane Library, Google Scholar, MEDLINE and IranMedex were searched. The studies that compared PET-scan with other diagnostic methods in terms of sensitivity, specificity and safety were considered in this review.Findings: PET-scan has been found to be a non-invasive and safe procedure for diagnosing metastatic NSCLC with a sensitivity and specificity of 74-95% and 81-97%, respectively. On the other hand, the sensitivity and specificity of computed tomography (CT) scan have been reported as 60-67% and 73-77%, respectively. The corresponding values for mediastinoscopy have been 78% and 100%. In lymphoma, the specificity and sensitivity of PET-scan (90% and 79-100%, respectively) have been higher than those of gamma scan. Although PET-scan is not an appropriate method for screening and diagnosis of cancer, it can contribute to staging and follow-up processes in cases of NSCLC and lymphoma. This technology adds 0.046 years (about 17 days) to the patient's life. Conclusion: PET-scan is a safe technology that has better diagnostic performance in comparison with similar technologies. The application of this method in staging and follow-up of NSCLC and lymphoma can prevent unnecessary surgeries and add a few years to the lives of patients.
کلیدواژهها [English]