Intracranial Extramedullary Hematopoiesis in a Patient with Intermediate B-Thalassemia

Document Type : Case Report

Authors

1 Associate Professor, Department of Pathology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.

2 Assistant Professor, Department of Neurosurgery, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.

3 Assistant Professor, Department of Pathology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.

4 Resident, Department of Pathology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.

Abstract

Background: Extramedullary hematopoiesis refers to formation of hematopoietic tissue and it is a compensatory phenomen in hematologic disease like congenital hemolytic anemia, myelofibrosis, pernicious anemia & Bone marrow infiltration secondary to malignancies. It has been reported in many sites but the most common sites are liver, spleen & lymph node.Case Report: A 34-year-old man with intermediate B-thalassemia had chronic headache and progressive loss of visual function. In CT scan a lobulated, non homogenous hyperdense mass was seen in left occipital horn with massive surrounding edema. In histologic examination the presence of hematopoietic tissue in brain parenchyma was confirmed.

Keywords

References

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Journal of Isfahan Medical School
Volume 29, Issue 134 - Serial Number 134
March and April 2011
Pages 403-408

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History

  • Receive Date: 15 March 2011
  • Revise Date:
  • Accept Date: 06 April 2022

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