Prevalence of Infection Associated with Central Venous Catheter and the Type of Pathogen and Its Related Factors in the Intensive Care Units of Ayatollah Kashani Hospital in Isfahan

Document Type : Original Article(s)

Authors

1 Associate Professor of Anesthesiology, Department of Anesthesiology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

2 Professor of Anesthesiology, School of Medicine, Anesthesiology and Critical Care Research Center, Isfahan University of Medical Sciences, Isfahan, Iran

3 School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

10.48305/jims.v43.i829.1050

Abstract

Background: Given the mortality rate and the cost of care associated with catheter-related infections and hospitalization, this study was conducted to investigate the prevalence of central venous catheter-related infection, the type of pathogen, and its related factors in the Intensive Care Units (ICUs) of Ayatollah Kashani Hospital in Isfahan.
Methods: In this cross-sectional study, 78 patients admitted to the ICU were evaluated for central venous catheter-related infections. Catheter implantation time, ICU length of stay, catheter location, disease severity (assessed using APACHE II criteria during catheter placement), and the type of antibiotic used were evaluated. After collecting data, a Chi-square test and frequency distribution table with related graphs were generated at an error level of 0.05 using SPSS software version 26.
Findings: Less than half of the patients (44.9%) showed central venous catheter infection. Also, more than half of the patients had gram-positive pathogens (52.6%) and the rest had gram-negative pathogens. There was a significant difference between gender, age and time of hospitalization, patients and the incidence of central venous catheter infection (P < 0.05). There was no significant difference between underlying diseases, disease severity using APACHE II criterion and type of antibiotic used with CRI in patients (P > 0.05). Frequency of CRI by location (femoral, jugular, subclavian) was observed in patients with central venous catheter admitted to ICU (P < 0.05) and the highest rate of central venous catheter infection was related to subclavian location (51.4%).
Conclusion: Lack of hygiene by medical staff is the most important factor in the incidence of infection caused by central venous catheter. Factors such as underlying disease, disease severity, and type of antibiotic used do not affect central venous catheter infection. The best location is the catheter, jugular and femoral.

Highlights

Seyed Taghi Hashemi: Google Scholar

Babak Alikiaii: Google Scholar

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References

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Journal of Isfahan Medical School
Volume 43, Issue 829
1st Week, November
November and December 2025
Pages 1050-1057

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History

  • Receive Date: 18 April 2025
  • Accept Date: 12 July 2025

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