نوع مقاله : مقاله های پژوهشی
نویسندگان
1 دانشجوی کارشناسی ارشد، گروه فیزیک پزشکی، دانشکدهی پزشکی، دانشگاه علوم پزشکی اصفهان، اصفهان، ایران
2 دانشیار، گروه رادیوانکولوژی، دانشکدهی پزشکی، بیمارستان سیدالشهدا، دانشگاه علوم پزشکی اصفهان، اصفهان، ایران
3 کارشناسی ارشد فیزیک پزشکی، بیمارستان سیدالشهدا، دانشگاه علوم پزشکی اصفهان، اصفهان، ایران
4 دکتری فیزیک پزشکی، گروه فیزیک پزشکی، دانشکدهی پزشکی، اصفهان، ایران
5 استاد، گروه فیزیک پزشکی، دانشکدهی پزشکی، دانشگاه علوم پزشکی اصفهان، اصفهان، ایران
چکیده
کلیدواژهها
موضوعات
عنوان مقاله [English]
نویسندگان [English]
Background: Head and neck cancer (HNC) is among the ten most common cancers worldwide. Due to the complex anatomy of the head and neck, many organs receive radiation during treatment. The aim of this study is to compare the dose received by the cochlea in two different treatment methods, 3D-CRT (Three-Dimensional Conformal Radiotherapy) and HT (Helical Tomotherapy).
Methods: The current study is applied and cross-sectional. 28 patients who had nasopharyngeal cancer and were referred to Seyed al-Shohada Hospital (Omid) for treatment between 2020-2022 and were candidates for treatment with one of the 3D-CRT or HT devices; were included in this study. The treatment plan for each patient was simulated in two devices and then study variables such as maximum and average dose and homogeneity and conformity index were investigated.
Findings: Comparison of the treatment plans using Helical Tomotherapy (HT) and Three-Dimensional Conformal Radiation Therapy (3D-CRT), Showed that the average dose received by organs at risk, such as the cochlea, was significantly lower in the HT method compared to the 3D-CRT method. This indicating a significant difference between the two treatment methods.
Conclusion: Our study on patients with nasopharyngeal cancer revealed that Helical Tomotherapy (HT) treatment led to better target homogeneity and compliance compared to conventional Three-Dimensional Conformal Radiation Therapy (3D-CRT). Additionally, HT was found to reduce the dose delivered to organs at risk (OARs) compared to 3D-CRT.
کلیدواژهها [English]