Isfahan University of Medical Sciences Journal of Isfahan Medical School 1027-7595 25 86 2007 09 23 Evaluation of Neurologic and Adaptive Capacity Score after Induction with Thiopental in Cesarean Section Evaluation of Neurologic and Adaptive Capacity Score after Induction with Thiopental in Cesarean Section 110 106 12929 FA Mitra Jabalameli Hajar Barati Sharareh Taheri Journal Article 2010 11 07 BACKGROUND: The neurologic and adaptive capacity score (NACS) is a multi-item scale to measure the effects of intrapartum drugs on the neonate. The purpose of this study was to assess NACS after induction with thiopental. METHODS: In this prospective study, for 76 elective cesarean section parturient, anesthesia induced with thiopental 4 mg/kg, succinyl choline 1.5 mg/kg and maintained with halothane and N2O/O2 (50/50). Iv fluids and all drugs administration were similar in all patients. Apgar (1th, 5th) and NACS were checked 15 minutes, 2 and 24 hours after birth. FINDINGS: Eleven neonates (%14/4) had NACS≤34, 15 minutes after birth. Only two neonates had NACS≤34, 2 hours after birth. None of them had no NACS≤34, 24 hours after birth. There was significant difference for NACS in all 3 times (p=0.0001). The most frequency of NACS was 38-40 in all the times. CONCLUSION: There was no significant changes in neuro adaptive and Apgar scores clinically. There was direct correlation between NACS and Apgar in all the times. KEY WORDS: NACS, thiopental, Apgar, induction, cesarean BACKGROUND: The neurologic and adaptive capacity score (NACS) is a multi-item scale to measure the effects of intrapartum drugs on the neonate. The purpose of this study was to assess NACS after induction with thiopental. METHODS: In this prospective study, for 76 elective cesarean section parturient, anesthesia induced with thiopental 4 mg/kg, succinyl choline 1.5 mg/kg and maintained with halothane and N2O/O2 (50/50). Iv fluids and all drugs administration were similar in all patients. Apgar (1th, 5th) and NACS were checked 15 minutes, 2 and 24 hours after birth. FINDINGS: Eleven neonates (%14/4) had NACS≤34, 15 minutes after birth. Only two neonates had NACS≤34, 2 hours after birth. None of them had no NACS≤34, 24 hours after birth. There was significant difference for NACS in all 3 times (p=0.0001). The most frequency of NACS was 38-40 in all the times. CONCLUSION: There was no significant changes in neuro adaptive and Apgar scores clinically. There was direct correlation between NACS and Apgar in all the times. KEY WORDS: NACS, thiopental, Apgar, induction, cesarean https://jims.mui.ac.ir/article_12929_0ac2e9dc0810e7a46d37c8070285c9ef.pdf