Isfahan University of Medical Sciences Journal of Isfahan Medical School 1027-7595 28 114 2010 12 22 Comparing the Frequency of Sensorineural Hearing loss and Neurological Disorders, Speech Perception in Patients with Multiple Sclerosis and Healthy People Comparing the Frequency of Sensorineural Hearing loss and Neurological Disorders, Speech Perception in Patients with Multiple Sclerosis and Healthy People 843 847 13183 FA Nezamoddin Berjis Professor, Department of Otolarhngology, Head and Neck Surgery, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran 0000-0001-8761-3640 Masoud Etemadifar Associate Professor, Department of Neurology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran 0000-0002-0066-3782 Ahmad Chitsaz Associate Professor, Department of Neurology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran Masoud Maleki Medical Student, Isfahan University of Medical Sciences, Isfahan, Iran Azadeh Kadkhodaei Medical Student, Isfahan University of Medical Sciences, Isfahan, Iran Journal Article 2011 03 03 Background: Multipe sclerosis (MS) is a demyelinative disease of central nervous system which because of high prevalence and high morbidity is in the focus of scientists’ attention. Hearing loss in 6-10% of patients with MS is seen. Also, impaired speech reception threshold is 40-50% in MS patients. The aim of this study was comparing the prevalence of sensorinural hearing loss and impaired speech reception threshold in MS and control groups.Methods: In a case-control cross-sectional study, 112 patients with MS and 112 healthy people in control group were assessed in Isfahan. Demographic findings, presenting symptoms and number of lesion in MRI were obtained.Finding: From 112 patients with MS, 75% were women. The age was 28.02 ± 6.6 years in MS group and 25.22 ± 3.8 years in control group. In this study, sensorineural hearing loss in patients with MS was 40.2% compared to 6.3% in controls (P < 0.001). Also, sensorineural hearing loss prevalence in women (40.5%) was more than men (39.3%) in MS group. There prevalence of mild and profound impaired speech reception threshold was 33.9% and 1.8% respectively; while there was moderate impaired speech reception threshold only in 0.9% of our control group. Speech reception threshold of all women in control group was normal and only one man (3.5%) had impaired speech reception threshold in control group (P = 0.33).Discussion: In patients with MS, the prevalence of sensorineural hearing loss and impaired speech reception threshold were like recent studies. Higher age may be a potential source of sensorineural hearing loss in MS group. Women sexuality may be a potential source of impaired speech reception threshold. Background: Multipe sclerosis (MS) is a demyelinative disease of central nervous system which because of high prevalence and high morbidity is in the focus of scientists’ attention. Hearing loss in 6-10% of patients with MS is seen. Also, impaired speech reception threshold is 40-50% in MS patients. The aim of this study was comparing the prevalence of sensorinural hearing loss and impaired speech reception threshold in MS and control groups.Methods: In a case-control cross-sectional study, 112 patients with MS and 112 healthy people in control group were assessed in Isfahan. Demographic findings, presenting symptoms and number of lesion in MRI were obtained.Finding: From 112 patients with MS, 75% were women. The age was 28.02 ± 6.6 years in MS group and 25.22 ± 3.8 years in control group. In this study, sensorineural hearing loss in patients with MS was 40.2% compared to 6.3% in controls (P < 0.001). Also, sensorineural hearing loss prevalence in women (40.5%) was more than men (39.3%) in MS group. There prevalence of mild and profound impaired speech reception threshold was 33.9% and 1.8% respectively; while there was moderate impaired speech reception threshold only in 0.9% of our control group. Speech reception threshold of all women in control group was normal and only one man (3.5%) had impaired speech reception threshold in control group (P = 0.33).Discussion: In patients with MS, the prevalence of sensorineural hearing loss and impaired speech reception threshold were like recent studies. Higher age may be a potential source of sensorineural hearing loss in MS group. Women sexuality may be a potential source of impaired speech reception threshold. https://jims.mui.ac.ir/article_13183_a188af0bc920853d3673ab71c5f2a440.pdf