Isfahan University of Medical Sciences Journal of Isfahan Medical School 1027-7595 29 139 2011 06 22 Hormonal Receptors Evaluation in Breast Cancer Hormonal Receptors Evaluation in Breast Cancer 621 625 13435 FA Fereshteh Kamani Assistant Professor, Department of General Surgery, Taleghani Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Afshin Fathi Resident, Department of General Surgery, Taleghani Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Journal Article 2010 11 21 Background: Breast cancer is the most common site-specific cancer in women and is of the major leading causes of death from cancer for women aged 20 to 59 years. This study aimed to demonstrate certain biological, clinical and pathological characteristics and to evaluate the breast receptors of patients with this disease.Methods: In this retrospective and descriptive study, 54 patients with breast cancer were selected to participate. All the cases were treated by modified radical mastectomy (MRM). Data was gathered from patients’ records.Finding: The mean age at which breast cancer was first diagnosed, was 50.23 years (Range: 32-75, SD = 11.00 years) and 86.8% of tumors were invasive ductal carcinoma. The mean tumor size was 4.95 cm (Range: 1-11, SD = 2.64 cm). 39 cases were estrogen receptor positive (72.22%) that 19 of them were in patients with right breast tumor. 12 patients (80%) of 15 cases with negative estrogen receptor, had tumor in right breast. In 33 cases which were progesteron receptor positive, 17 had right breast tumor. 14 patients, of 21 cases with negative progesterone receptor, had tumor in right breast.Conclusion: Most of the patients with negative estrogen or progesterone receptor, had tumors in right breast. So, it may be an important proposition in breast cancer world to discover more about it. Background: Breast cancer is the most common site-specific cancer in women and is of the major leading causes of death from cancer for women aged 20 to 59 years. This study aimed to demonstrate certain biological, clinical and pathological characteristics and to evaluate the breast receptors of patients with this disease.Methods: In this retrospective and descriptive study, 54 patients with breast cancer were selected to participate. All the cases were treated by modified radical mastectomy (MRM). Data was gathered from patients’ records.Finding: The mean age at which breast cancer was first diagnosed, was 50.23 years (Range: 32-75, SD = 11.00 years) and 86.8% of tumors were invasive ductal carcinoma. The mean tumor size was 4.95 cm (Range: 1-11, SD = 2.64 cm). 39 cases were estrogen receptor positive (72.22%) that 19 of them were in patients with right breast tumor. 12 patients (80%) of 15 cases with negative estrogen receptor, had tumor in right breast. In 33 cases which were progesteron receptor positive, 17 had right breast tumor. 14 patients, of 21 cases with negative progesterone receptor, had tumor in right breast.Conclusion: Most of the patients with negative estrogen or progesterone receptor, had tumors in right breast. So, it may be an important proposition in breast cancer world to discover more about it. https://jims.mui.ac.ir/article_13435_ab7c2d6f143b42faf360c6b52fcc2f05.pdf