Isfahan University of Medical Sciences Journal of Isfahan Medical School 1027-7595 41 726 2023 08 23 Serum Levels of the Vitamin D and Zinc in Adolescents Aged 10 to 19 Years in Mashhad Serum Levels of the Vitamin D and Zinc in Adolescents Aged 10 to 19 Years in Mashhad 536 542 31013 10.48305/jims.v41.i726.0536 FA Azam Shafaei MSc of Clinical Biochemistry, Blood Borne Infections Research Center, Academic Center for Education, Culture and Research (ACECR), Razavi Khorasan Branch, Mashhad, Iran 0000-0003-1189-3185 Seyyed Ali Akbar Shamsian Professor, Department of Parasitology and Mycology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran 0000-0001-5048-4857 Mohammad Ghodsi PhD in Cell and Developmental Biology, Blood Borne Infections Research Center, Academic Center for Education, Culture and Research (ACECR), Razavi Khorasan Branch, Mashhad, Iran 0000-0003-2955-8553 Maryam Shahi PhD of Molecular Medicine, Blood Borne Infections Research Center, Academic Center for Education, Culture and Research (ACECR), Razavi Khorasan Branch, Mashhad, Iran 0000-0003-2822-0315 Journal Article 2023 01 17 Background: Vitamin D and zinc play an essential role in growth and health of children and adolescents. The aim of this study was to investigate the prevalence of vitamin D and zinc deficiency among adolescents in Mashhad. Methods: This descriptive cross-sectional study was conducted on 3380 adolescents aged 10-19 years from October 2020 to September 2022. Vitamin D level was evaluated by high performance liquid chromatography and zinc level was investigated by colorimetric technique. The studied subjects were divided into three groups in terms of vitamin D levels: deficiency: <10 ng/mL, insufficient levels: 10-30 ng/mL, normal levels: 30-100 ng/mL, and according to the amount of zinc, they are divided into two groups: deficiency: <60 µg/dL and normal: 60-120 µg/dL. The results were analyzed using chi-square and regression tests. Findings: Out of 3380 adolescents, 69.1% were girls and 30.9% were boys. Among the studied adolescents, 11.4% had vitamin D deficiency, 51.9% had insufficient vitamin D, and 36.7% had normal vitamin D levels. Zinc deficiency was observed in 7.4% of the studied groups. The prevalence of vitamin D and zinc deficiency was higher in girl adolescents than in boy adolescents (P < 0.001). The study results showed that the low level of zinc in the studied adolescents is not a risk factor for vitamin D deficiency. Conclusion: The prevalence of vitamin D deficiency in adolescents, particularly among girls, is high in the city of Mashhad. It is recommended to address malnutrition through the use of fortified foods and dietary supplements. Background: Vitamin D and zinc play an essential role in growth and health of children and adolescents. The aim of this study was to investigate the prevalence of vitamin D and zinc deficiency among adolescents in Mashhad. Methods: This descriptive cross-sectional study was conducted on 3380 adolescents aged 10-19 years from October 2020 to September 2022. Vitamin D level was evaluated by high performance liquid chromatography and zinc level was investigated by colorimetric technique. The studied subjects were divided into three groups in terms of vitamin D levels: deficiency: <10 ng/mL, insufficient levels: 10-30 ng/mL, normal levels: 30-100 ng/mL, and according to the amount of zinc, they are divided into two groups: deficiency: <60 µg/dL and normal: 60-120 µg/dL. The results were analyzed using chi-square and regression tests. Findings: Out of 3380 adolescents, 69.1% were girls and 30.9% were boys. Among the studied adolescents, 11.4% had vitamin D deficiency, 51.9% had insufficient vitamin D, and 36.7% had normal vitamin D levels. Zinc deficiency was observed in 7.4% of the studied groups. The prevalence of vitamin D and zinc deficiency was higher in girl adolescents than in boy adolescents (P < 0.001). The study results showed that the low level of zinc in the studied adolescents is not a risk factor for vitamin D deficiency. Conclusion: The prevalence of vitamin D deficiency in adolescents, particularly among girls, is high in the city of Mashhad. It is recommended to address malnutrition through the use of fortified foods and dietary supplements.

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