Isfahan University of Medical Sciences Journal of Isfahan Medical School 1027-7595 42 785 2024 11 21 Comparing the Effectiveness of Oral Corticosteroids, Pineapple Extract, and Placebo in Treating Ecchymosis and Edema after Rhinoplasty Surgery Comparing the Effectiveness of Oral Corticosteroids, Pineapple Extract, and Placebo in Treating Ecchymosis and Edema after Rhinoplasty Surgery 850 856 31333 10.48305/jims.v42.i785.0850 FA Seyed Mostafa Hashemi Professor, Department of Otorhinolaryngology, Head and Neck Surgery, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran 0000-0002-4067-6326 Mahsa Ghanbari Assistant Professor, Department of Ear, Nose and Throat, Faculty of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran 0009-0009-6710-1870 Samad Sarnameh Resident, Department of Otorhinolaryngology, Head and Neck Surgery, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran 0009-0005-8434-9860 Journal Article 2024 06 17 <strong>Background:</strong><em> </em> One of the unwanted effects after rhinoplasty surgery is ecchymosis and edema. Considering the importance of the health and satisfaction of patients after rhinoplasty surgery, proper and efficient management is one of the first goals of doctors after surgery. As a result, the purpose of this research is to compare the intensity of the effect of oral corticosteroid and pineapple extract and placebo on the treatment of ecchymosis and edema after rhinoplasty surgery. <strong>Methods:</strong><strong> </strong>The statistical population includes people who went to Al-Zahra Hospital and Kashani Hospital for rhinoplasty surgery in 2023. Patients were randomly selected from among 60 patients referred for rhinoplasty surgery, who were randomly divided into appropriate groups treated with placebo, oral corticosteroids, and pineapple extract. <strong>Findings:</strong><strong> </strong>The findings showed that there is no significant difference between the effect of oral corticosteroid and pineapple extract and placebo on the treatment of ecchymosis and edema one day and two weeks after rhinoplasty surgery; However, there is a significant difference between the effect of oral corticosteroid and pineapple extract and placebo on the treatment of ecchymosis and edema one week after rhinoplasty surgery (P < 0.001). <strong>Conclusion:</strong> It is concluded that oral corticosteroids are more effective in treating ecchymosis and edema one week after surgery than rhinoplasty surgery. Oral corticosteroids can be used as an effective treatment method. Pineapple extract does not have a significant effect in reducing edema and ecchymosis after surgery, so extra costs can be avoided by preventing the administration of pineapple extract. <strong>Background:</strong><em> </em> One of the unwanted effects after rhinoplasty surgery is ecchymosis and edema. Considering the importance of the health and satisfaction of patients after rhinoplasty surgery, proper and efficient management is one of the first goals of doctors after surgery. As a result, the purpose of this research is to compare the intensity of the effect of oral corticosteroid and pineapple extract and placebo on the treatment of ecchymosis and edema after rhinoplasty surgery. <strong>Methods:</strong><strong> </strong>The statistical population includes people who went to Al-Zahra Hospital and Kashani Hospital for rhinoplasty surgery in 2023. Patients were randomly selected from among 60 patients referred for rhinoplasty surgery, who were randomly divided into appropriate groups treated with placebo, oral corticosteroids, and pineapple extract. <strong>Findings:</strong><strong> </strong>The findings showed that there is no significant difference between the effect of oral corticosteroid and pineapple extract and placebo on the treatment of ecchymosis and edema one day and two weeks after rhinoplasty surgery; However, there is a significant difference between the effect of oral corticosteroid and pineapple extract and placebo on the treatment of ecchymosis and edema one week after rhinoplasty surgery (P < 0.001). <strong>Conclusion:</strong> It is concluded that oral corticosteroids are more effective in treating ecchymosis and edema one week after surgery than rhinoplasty surgery. Oral corticosteroids can be used as an effective treatment method. Pineapple extract does not have a significant effect in reducing edema and ecchymosis after surgery, so extra costs can be avoided by preventing the administration of pineapple extract. https://jims.mui.ac.ir/article_31333_7560d81fe93291a77fe0c856f1e985b9.pdf