Isfahan University of Medical SciencesJournal of Isfahan Medical School1027-75954070420230220The Relationship between Sleep Apnea and Pulmonary Function in Workers of One of the Aluminum IndustriesThe Relationship between Sleep Apnea and Pulmonary Function in Workers of One of the Aluminum Industries112111273035310.48305/jims.v40.i704.1121FAHadiEshaghi Sani KakhakAssistant Professor, Department of Occupational Medicine, School of Medicine, Hormozgan University of Medical Sciences, Bandar Abbas, Iran0000-0003-2188-5277KianaHidarpoorDepartment of Occupational Medicine, School of Medicine, Hormozgan University of Medical Sciences, Bandar Abbas, IranMehdiZareAssociate Professor, Occupational Health, Hormozgan University Medical Sciences, Bandar Abbas, Iran0000-0002-5424-1083َAlirezaAmanollahiAssociate Professor, Department of Epidemiology, School of Public Health and Safety, Shahid Beheshti University of Medical Sciences, Tehran, Iran0000-0003-1056-5438MehdiBehjati ArdakaniAssistant Professor, Occupational Health, Hormozgan University Medical Sciences, Bandar Abbas, Iran0000-0002-3250-4030Journal Article20220528<strong>Background:</strong><em> </em>Respiratory sleep disorder is one of the most common sleep disorders. The aim of this study was to investigate the factors affecting sleep apnea in workers working in one of the aluminum industries.
<strong>Methods:</strong><strong> </strong>This descriptive-analytical study was conducted in one of the aluminum industries in the south of Iran in 2021. The lung capacity of the workers was assessed according to the guidelines of the American Association of Lung Specialists. Berlin questionnaires were used to assess obstructive sleep apnea. Data were analyzed using T-test, Pearson correlation coefficient, and multiple logistic regression.
<strong>Findings:</strong><strong> </strong>In this study, 152 workers in the aluminum industry with an average age of 33.63 ± 6.34 years and a body mass index of 25.06 ± 3.07 participated. 34.9% of workers were at high risk for obstructive sleep apnea. Age (OR = 1.23, 95% CI = 1.08-1.37), body mass index (OR = 1.57, 95% CI = 1.18-2.08), and FEV1 / FVC (OR = 0.76, 95% CI = 0.59-0.98) were significantly associated with an increased risk of sleep apnea (P < 0.001)
<strong>Conclusion:</strong> Workers, in the aluminum industry, have a higher risk of developing obstructive sleep apnea. Age, body mass index, and FEV<sub>1</sub> / FVC are the main predictors of sleep apnea. These variables should be considered in the screening tests and clinical trials.<strong>Background:</strong><em> </em>Respiratory sleep disorder is one of the most common sleep disorders. The aim of this study was to investigate the factors affecting sleep apnea in workers working in one of the aluminum industries.
<strong>Methods:</strong><strong> </strong>This descriptive-analytical study was conducted in one of the aluminum industries in the south of Iran in 2021. The lung capacity of the workers was assessed according to the guidelines of the American Association of Lung Specialists. Berlin questionnaires were used to assess obstructive sleep apnea. Data were analyzed using T-test, Pearson correlation coefficient, and multiple logistic regression.
<strong>Findings:</strong><strong> </strong>In this study, 152 workers in the aluminum industry with an average age of 33.63 ± 6.34 years and a body mass index of 25.06 ± 3.07 participated. 34.9% of workers were at high risk for obstructive sleep apnea. Age (OR = 1.23, 95% CI = 1.08-1.37), body mass index (OR = 1.57, 95% CI = 1.18-2.08), and FEV1 / FVC (OR = 0.76, 95% CI = 0.59-0.98) were significantly associated with an increased risk of sleep apnea (P < 0.001)
<strong>Conclusion:</strong> Workers, in the aluminum industry, have a higher risk of developing obstructive sleep apnea. Age, body mass index, and FEV<sub>1</sub> / FVC are the main predictors of sleep apnea. These variables should be considered in the screening tests and clinical trials.https://jims.mui.ac.ir/article_30353_6a12f449790ed7be96d77aa4c7d9c1c1.pdfIsfahan University of Medical SciencesJournal of Isfahan Medical School1027-75954070420230220Comparing the Effect of Six Weeks of Aerobic and Resistance Training on Expression miR-195 in Male Rats with Diabetic CardiomyopathyComparing the Effect of Six Weeks of Aerobic and Resistance Training on Expression miR-195 in Male Rats with Diabetic Cardiomyopathy112811373035210.48305/jims.v40.i704.1128FAMajidKashefProfessor, Department of Sports Physiology, Shahid Rajaee Teacher Training University, Tehran, Iran0000-0001-8551-3371MojtabaSalehpourAssociate Professor, Department of Sports Physiology, Shahid Rajaee Teacher Training University, Tehran, Iran0000-0002-6208-2502FereshtehShahidiAssociate Professor, Department of Sports Physiology, Shahid Rajaee Teacher Training University, Tehran, IranNematallhNejatmandPhD Student, Cardiovascular and Respiratory Field, Shahid Rajaee Teacher Training University, Tehran, Iran0000-0002-0746-9261Journal Article20221221<strong>Background:</strong><em> </em>The main cause of death in diabetic patients is cardiomyopathy<em>.</em> Regular exercise improves insulin resistance and reduces the mortality of diabetic patients<em>.</em> The aim of this study was to compare the effect of six weeks of aerobic and resistance training on the expression of miR195 (specific to the myocardium) in male rats with diabetic cardiomyopathy.
<strong>Methods:</strong><strong> </strong>Male rats with an average weight of 200 ± 20 grams and age of 8 weeks were randomly divided into four groups of 6 (sham, control, resistance and aerobic training) after the induction of diabetes (50 mg/kg STZ). A healthy group (n = 6) was also considered for comparison with the diabetic group. Exercise protocols were performed for 6 weeks. The expression level of miR195 was evaluated using PCR-Real Time. One Way Anova and T-correlated statistical tests were used for data analysis.
<strong>Findings:</strong><strong> </strong>Both aerobic and resistance protocols led to a significant decrease in fasting blood glucose and insulin resistance index (HOMA-IR). Vvo2peak of the aerobic group and 1RM of the resistance group increased significantly. The expression of miR195 in the diagnostic and solar control groups was more different than the healthy group, but it was less in the exercise groups.
<strong>Conclusion:</strong> Compared to aerobic exercise, resistance training had a better effect on the expression of miR195 and diabetes indicators. Therefore, it is recommended that patients with cardiomyopathy should focus on resistance training.<strong>Background:</strong><em> </em>The main cause of death in diabetic patients is cardiomyopathy<em>.</em> Regular exercise improves insulin resistance and reduces the mortality of diabetic patients<em>.</em> The aim of this study was to compare the effect of six weeks of aerobic and resistance training on the expression of miR195 (specific to the myocardium) in male rats with diabetic cardiomyopathy.
<strong>Methods:</strong><strong> </strong>Male rats with an average weight of 200 ± 20 grams and age of 8 weeks were randomly divided into four groups of 6 (sham, control, resistance and aerobic training) after the induction of diabetes (50 mg/kg STZ). A healthy group (n = 6) was also considered for comparison with the diabetic group. Exercise protocols were performed for 6 weeks. The expression level of miR195 was evaluated using PCR-Real Time. One Way Anova and T-correlated statistical tests were used for data analysis.
<strong>Findings:</strong><strong> </strong>Both aerobic and resistance protocols led to a significant decrease in fasting blood glucose and insulin resistance index (HOMA-IR). Vvo2peak of the aerobic group and 1RM of the resistance group increased significantly. The expression of miR195 in the diagnostic and solar control groups was more different than the healthy group, but it was less in the exercise groups.
<strong>Conclusion:</strong> Compared to aerobic exercise, resistance training had a better effect on the expression of miR195 and diabetes indicators. Therefore, it is recommended that patients with cardiomyopathy should focus on resistance training.https://jims.mui.ac.ir/article_30352_650bbf5d3ffa2b7d9b8b36d62d667ced.pdfIsfahan University of Medical SciencesJournal of Isfahan Medical School1027-75954070420230220Unilateral Aggressive Ischemic Proliferative Retinopathy in a Child with Neurofibromatosis Type 1, A Case ReportUnilateral Aggressive Ischemic Proliferative Retinopathy in a Child with Neurofibromatosis Type 1, A Case Report113811422784310.48305/jims.v40.i704.1138FAMohammadMalekahmadiAssistant Professor, Department of Ophthalmology, Isfahan Eye Research Center, Isfahan University of Medical Sciences, Isfahan, Iran0000-0003-3814-8863AlirezaDehghaniProfessor, Department of Ophthalmology, Isfahan Eye Research Center, Isfahan University of Medical Sciences, Isfahan, Iran0000-0002-6313-0262HeshmatollahGhanbariProfessor, Department of Ophthalmology, Isfahan Eye Research Center, Isfahan University of Medical Sciences, Isfahan, Iran0000-0001-8781-5568MehdiTavakoliOphthalmologist, Department of Ophthalmology, Isfahan Eye Research Center, Isfahan University of Medical Sciences, Isfahan, Iran0000-0002-4631-9178Journal Article20221210<strong>Background:</strong><em> </em>Neurofibromatosis is one of the phacomatosis syndromes that affects different organs in the body and is divided into two types. Neurofibromatosis type 1 can cause eye involvement in various forms, including eyelid, conjunctiva, iris or optic nerve involvement. Involvement of retinal vessels in the form of retinal ischemia is rare in this disease and usually occurs in the second or third decades of life and is controlled by laser treatment or surgery.<br /><strong>Case Report:</strong><strong> </strong>In this report, we introduce a 3-year-old girl with neurofibromatosis type 1 who suffered severe retinal ischemia. This child suffered unilateral retinal involvement in the form of ischemic retinopathy with retinal and vitreous hemorrhage in her left eye, and despite two vitrectomy and retinal laser surgery in the left eye, the retinal involvement progressed and eventually the vision in the left eye was lost.<br /><strong>Conclusion:</strong> This report shows for the first-time retinal involvement at a young age in a patient with neurofibromatosis type 1 and its resistant nature.<strong>Background:</strong><em> </em>Neurofibromatosis is one of the phacomatosis syndromes that affects different organs in the body and is divided into two types. Neurofibromatosis type 1 can cause eye involvement in various forms, including eyelid, conjunctiva, iris or optic nerve involvement. Involvement of retinal vessels in the form of retinal ischemia is rare in this disease and usually occurs in the second or third decades of life and is controlled by laser treatment or surgery.<br /><strong>Case Report:</strong><strong> </strong>In this report, we introduce a 3-year-old girl with neurofibromatosis type 1 who suffered severe retinal ischemia. This child suffered unilateral retinal involvement in the form of ischemic retinopathy with retinal and vitreous hemorrhage in her left eye, and despite two vitrectomy and retinal laser surgery in the left eye, the retinal involvement progressed and eventually the vision in the left eye was lost.<br /><strong>Conclusion:</strong> This report shows for the first-time retinal involvement at a young age in a patient with neurofibromatosis type 1 and its resistant nature.https://jims.mui.ac.ir/article_27843_dfe038a9e495e62ccd74953c05f7bc71.pdf