Isfahan University of Medical SciencesJournal of Isfahan Medical School1027-75954276620240621Radiographic Measurement of Posterior Tibial Slope in Healthy Iranian Adults: A Retrospective Cohort StudyRadiographic Measurement of Posterior Tibial Slope in Healthy Iranian Adults: A Retrospective Cohort Study3513583123810.48305/jims.v42.i766.351FAMohammad GhasemHanafiAssociate Professor of Radiology, Department of Radiology, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran0000-0003-1533-5244SanaHeidariResident of Medicine, Department of Radiology, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran0009-0000-1947-8758HamidrezaArtiProfessor of Orthopedic, Department of Orthopedics, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran0009-0000-1947-8758ElhamFarhadiClinical Research Development Unit, Golestan Hospital, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IranJournal Article20230813<strong>Background:</strong><em> </em>Posterior tibial slope (PTS) is a crucial radiographic measurement to determine the tibial plateau angle relative to its shaft.
<strong>Methods:</strong><strong> </strong>In this study, PACS images related to 612 patients who had visited the hospital for reasons such as knee injury or pain, physical examination, or knee reevaluation and had undergone X-ray examination were examined. PTS measurements were obtained using the GE CENTRICITY PACS software and subjected to analysis.
<strong>Findings:</strong><strong> </strong>The distribution of mean PTS in right and left angles revealed no significant difference between the two groups (P = 0.830). Comparing the mean PTS distribution between men and women, there was no significant difference in left and right PTS (P > 0.05). Additionally, comparing mean PTS between the right and left sides across different age groups showed statistically significant differences (P < 0.001).
<strong>Conclusion:</strong> This study identified the normal range of PTS values in knee joints of healthy Iranian adults, which can serve as a guide for personalized treatments. We hope that the results of this study will encourage knee prosthesis manufacturers to consider the obtained PTS measurements, as well as gender and age differences, in their product development for the Iranian population.<strong>Background:</strong><em> </em>Posterior tibial slope (PTS) is a crucial radiographic measurement to determine the tibial plateau angle relative to its shaft.
<strong>Methods:</strong><strong> </strong>In this study, PACS images related to 612 patients who had visited the hospital for reasons such as knee injury or pain, physical examination, or knee reevaluation and had undergone X-ray examination were examined. PTS measurements were obtained using the GE CENTRICITY PACS software and subjected to analysis.
<strong>Findings:</strong><strong> </strong>The distribution of mean PTS in right and left angles revealed no significant difference between the two groups (P = 0.830). Comparing the mean PTS distribution between men and women, there was no significant difference in left and right PTS (P > 0.05). Additionally, comparing mean PTS between the right and left sides across different age groups showed statistically significant differences (P < 0.001).
<strong>Conclusion:</strong> This study identified the normal range of PTS values in knee joints of healthy Iranian adults, which can serve as a guide for personalized treatments. We hope that the results of this study will encourage knee prosthesis manufacturers to consider the obtained PTS measurements, as well as gender and age differences, in their product development for the Iranian population.https://jims.mui.ac.ir/article_31238_4c4aa2205676a162ba900d37ea48e67d.pdfIsfahan University of Medical SciencesJournal of Isfahan Medical School1027-75954276620240621Investigating the Preventive Effect of Two Different Doses of Dexmedetomidine on the Incidence of Cough and Hemodynamics During Tracheal Tube Removal Compared to The Control Group: A Randomized Controlled TrialInvestigating the Preventive Effect of Two Different Doses of Dexmedetomidine on the Incidence of Cough and Hemodynamics During Tracheal Tube Removal Compared to The Control Group: A Randomized Controlled Trial3593683123010.48305/jims.v42.i766.359FAAzimHonarmandProfessor, Department of Anesthesiology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran0000-0002-2373-9241Mohammad RezaSafaviProfessor, Department of Anesthesiology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran0000-0002-8975-7661AtefeSaeidiMedical Student, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran0009-0000-2212-4678Journal Article20240325<strong>Background:</strong><em> </em>This study aimed to compare the preventive effect of two different doses of dexmedetomidine infusion compared to the control group on the incidence of cough and respiratory complications during tracheal tube removal.
<strong>Methods:</strong><strong> </strong>105 patients undergoing tracheal intubation were divided into three groups of 35 people, and in the three mentioned groups, at the end of the procedure, ten minutes before the tracheal tube was removed, the patients of group one received 0.5 μg/kg dexmedetomidine bolus and then 0.3 μg/kg infusion, group two 0.5 μg/kg dexmedetomidine bolus and then 0.5 μg/kg infusion and group three 10 minutes before leaving the endotracheal tube normal saline with equal volume of group one and two as bolus and then with equal volume of other two groups They received it as an infusion and the frequency and severity of cough and hemodynamic parameters were evaluated and compared in three groups.
<strong>Findings:</strong><strong> </strong>33 (31.4%) developed cough, of which 7 (20%) were from the dexmedetomidine 0.5 group, 9 people (25.7%) were from the dexmedetomidine 0.3 group, and 17 (48.6%) were from the control group. There was a significant difference in the cough frequency among the three groups (P = 0.024). In terms of severity, 10 (30.3%) patients had severe coughs, 2 (22.2%) were from the dexmedetomidine 0.3 group and 8 (47.1%) were from the control group. There was no case of severe cough in the dexmedetomidine 0.5 group. There was a significant difference in the cough severity among the three groups (P = 0.009).
<strong>Conclusion:</strong> An infusion dose of 0.5 μg/kg of dexmedetomidine followed by a bolus dose of 0.5 μg/kg of dexmedetomidine is associated with a decrease in the incidence and severity of cough after surgery and with more stable hemodynamics of patients.<strong>Background:</strong><em> </em>This study aimed to compare the preventive effect of two different doses of dexmedetomidine infusion compared to the control group on the incidence of cough and respiratory complications during tracheal tube removal.
<strong>Methods:</strong><strong> </strong>105 patients undergoing tracheal intubation were divided into three groups of 35 people, and in the three mentioned groups, at the end of the procedure, ten minutes before the tracheal tube was removed, the patients of group one received 0.5 μg/kg dexmedetomidine bolus and then 0.3 μg/kg infusion, group two 0.5 μg/kg dexmedetomidine bolus and then 0.5 μg/kg infusion and group three 10 minutes before leaving the endotracheal tube normal saline with equal volume of group one and two as bolus and then with equal volume of other two groups They received it as an infusion and the frequency and severity of cough and hemodynamic parameters were evaluated and compared in three groups.
<strong>Findings:</strong><strong> </strong>33 (31.4%) developed cough, of which 7 (20%) were from the dexmedetomidine 0.5 group, 9 people (25.7%) were from the dexmedetomidine 0.3 group, and 17 (48.6%) were from the control group. There was a significant difference in the cough frequency among the three groups (P = 0.024). In terms of severity, 10 (30.3%) patients had severe coughs, 2 (22.2%) were from the dexmedetomidine 0.3 group and 8 (47.1%) were from the control group. There was no case of severe cough in the dexmedetomidine 0.5 group. There was a significant difference in the cough severity among the three groups (P = 0.009).
<strong>Conclusion:</strong> An infusion dose of 0.5 μg/kg of dexmedetomidine followed by a bolus dose of 0.5 μg/kg of dexmedetomidine is associated with a decrease in the incidence and severity of cough after surgery and with more stable hemodynamics of patients.https://jims.mui.ac.ir/article_31230_8ebef38fe0b242f7c7a87e7f5b2de305.pdfIsfahan University of Medical SciencesJournal of Isfahan Medical School1027-75954276620240621Determining the Frequency of Pathogenic Yeasts in Clinical Urine Samples and Tracking the Trichosporon Using Gold NanoparticlesDetermining the Frequency of Pathogenic Yeasts in Clinical Urine Samples and Tracking the Trichosporon Using Gold Nanoparticles3693763124210.48305/jims.v42.i766.369FAImanZareiMSc Student of Medical Mycology, Department of Mycology and Parasitology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran0000-0002-0702-4537HosseinYousofi DaraniProfessor, Department of Mycology and Parasitology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran0000-0002-9099-7160ParvinDehghanProfessor, Department of Mycology and Parasitology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran0000-0002-0000-6643Journal Article20240409<strong>Background:</strong><em> </em>Timely identification and treatment of trichosporonosis is consequential due to the severity of pathogenesis and different therapies for candidiasis and its high mortality. In this study, in addition to determining the abundance of this fungus in clinical urine samples using past experiences in the function of gold nanoparticles, identification of this yeast based on serological methods for rapid detection of yeast in urine samples has been presented.
<strong>Methods:</strong><strong> </strong>249 samples of people suspected of urinary fungal infection were analyzed using morphological and molecular PCR-RFLP methods. Antigenic suspension was prepared from different species of <em>Trichosporon</em>. This mixture was injected with a complete adjuvant to a healthy rabbit. After injecting four booster doses using incomplete adjuvant, blood was drawn from the rabbit. The anti-fungal antibody ability in the rabbit serum was confirmed using the ELISA method. Then, the antibody was placed chemically on the surface of gold nanoparticles, and the method's performance was investigated.
<strong>Findings:</strong><strong> </strong><em>C. glabrata and C. albicans</em> species were the most common yeasts isolated. Among isolated yeasts, four cases of <em>Trichosporon</em> in urinary samples (1.6%) were reported. In this study, diabetes and corona disease were the underlying factors, and similar studies confirm the role of these factors. The serological method based on gold nanoparticles has been used in other studies to detect pathogens.
<strong>Conclusion:</strong> The frequency of <em>trichosporon</em> in urine was 1.6% during the study period. In this study, diabetes and Coronavirus disease were the main predisposing factors, and similar studies confirm the role of these factors. The serological method based on gold nanoparticles has been used in other studies to detect pathogens.<strong>Background:</strong><em> </em>Timely identification and treatment of trichosporonosis is consequential due to the severity of pathogenesis and different therapies for candidiasis and its high mortality. In this study, in addition to determining the abundance of this fungus in clinical urine samples using past experiences in the function of gold nanoparticles, identification of this yeast based on serological methods for rapid detection of yeast in urine samples has been presented.
<strong>Methods:</strong><strong> </strong>249 samples of people suspected of urinary fungal infection were analyzed using morphological and molecular PCR-RFLP methods. Antigenic suspension was prepared from different species of <em>Trichosporon</em>. This mixture was injected with a complete adjuvant to a healthy rabbit. After injecting four booster doses using incomplete adjuvant, blood was drawn from the rabbit. The anti-fungal antibody ability in the rabbit serum was confirmed using the ELISA method. Then, the antibody was placed chemically on the surface of gold nanoparticles, and the method's performance was investigated.
<strong>Findings:</strong><strong> </strong><em>C. glabrata and C. albicans</em> species were the most common yeasts isolated. Among isolated yeasts, four cases of <em>Trichosporon</em> in urinary samples (1.6%) were reported. In this study, diabetes and corona disease were the underlying factors, and similar studies confirm the role of these factors. The serological method based on gold nanoparticles has been used in other studies to detect pathogens.
<strong>Conclusion:</strong> The frequency of <em>trichosporon</em> in urine was 1.6% during the study period. In this study, diabetes and Coronavirus disease were the main predisposing factors, and similar studies confirm the role of these factors. The serological method based on gold nanoparticles has been used in other studies to detect pathogens.https://jims.mui.ac.ir/article_31242_19ddc61af8f213d2c43c17204efab297.pdf