Isfahan University of Medical SciencesJournal of Isfahan Medical School1027-75953545820180121IndexIndex1543810.22122/jims.v35i458.10552FAJournalIndex0000-0003-0874-1906Journal Article20180729Click to download the index of this issue.Click to download the index of this issue.https://jims.mui.ac.ir/article_15438_a725c77dfdec0a53250d0709ed36e1fe.pdfIsfahan University of Medical SciencesJournal of Isfahan Medical School1027-75953545820180121An Automated Approach for Quantifying Emotional Conditions based on Electroencephalogram SignalsAn Automated Approach for Quantifying Emotional Conditions based on Electroencephalogram Signals173217371543910.22122/jims.v35i458.8759FAFahimehParsaeiMSc Student, Department of Cognitive Science (Cognitive Psychology), School of New Sciences and Technologies, Semnan University, Semnan, IranAliMalekiAssistant Professor, Department of Biomedical Engineering, School of Electrical and Computer Engineering, Semnan University, Semnan, Iran0000-0002-2405-4164Mohammad RezaDaliriAssociate Professor, Department of Biomedical Engineering, School of Electrical Engineering, Iran University of Science and Technology, Tehran, Iran0000-0001-9241-8751Journal Article20170906Background: Emotion is a psychological process of the mind. It not only has an important role in human interactions, but also has been the subject of attention in human-computer interactions in recent years. Because of diversity and uncertainty nature of the emotion, as well as the individuals’ inability to accurately and quantitatively express their emotions, a quantitative measure for emotion is needed. To describe different emotional states, we used arousal-valence two-dimensional model of emotion.Methods: To propose an approach for emotion recognition based on fuzzy clustering, individuals’ electroencephalogram signals during watching videos along with self-reports about their emotions were achieved from database for emotion analysis using physiological signals (DEAP). Three features of functional connectivity of the brain including correlation, phase locked value, and coherence were investigated and clustered using fuzzy c-means clustering approach. Finally, according to online rating and clustering results for each feature, quantitative and continuous values for valence and arousal were obtained.Findings: We achieved 0.901 ± 0.079 of valence accuracy and 0.860 ± 0.083 of arousal accuracy. Selected functional connections were related to simultaneous activation of visual, auditory, and sensory perception areas of brain cortex.Conclusion: The accuracy of the results was more than previous studies which were done on emotion recognition based on binary method. In addition, the results indicated that emotion estimation based on coherence had better accuracy than the other investigated features. This results for valence were more than previous studies. The results of this study are applicable in improving human-computer interactions as well as in the area of cognitive rehabilitation.Background: Emotion is a psychological process of the mind. It not only has an important role in human interactions, but also has been the subject of attention in human-computer interactions in recent years. Because of diversity and uncertainty nature of the emotion, as well as the individuals’ inability to accurately and quantitatively express their emotions, a quantitative measure for emotion is needed. To describe different emotional states, we used arousal-valence two-dimensional model of emotion.Methods: To propose an approach for emotion recognition based on fuzzy clustering, individuals’ electroencephalogram signals during watching videos along with self-reports about their emotions were achieved from database for emotion analysis using physiological signals (DEAP). Three features of functional connectivity of the brain including correlation, phase locked value, and coherence were investigated and clustered using fuzzy c-means clustering approach. Finally, according to online rating and clustering results for each feature, quantitative and continuous values for valence and arousal were obtained.Findings: We achieved 0.901 ± 0.079 of valence accuracy and 0.860 ± 0.083 of arousal accuracy. Selected functional connections were related to simultaneous activation of visual, auditory, and sensory perception areas of brain cortex.Conclusion: The accuracy of the results was more than previous studies which were done on emotion recognition based on binary method. In addition, the results indicated that emotion estimation based on coherence had better accuracy than the other investigated features. This results for valence were more than previous studies. The results of this study are applicable in improving human-computer interactions as well as in the area of cognitive rehabilitation.https://jims.mui.ac.ir/article_15439_65dfa16ba6de9bdb34ea435c9fe2a425.pdfIsfahan University of Medical SciencesJournal of Isfahan Medical School1027-75953545820180121Predictive Factors of Seizures in Patients with Organophosphate PoisoningPredictive Factors of Seizures in Patients with Organophosphate Poisoning173817431544010.22122/jims.v35i458.9208FAAhmadYaraghiProfessor, Isfahan Clinical Toxicology Research Center, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran0000-0001-8532-9005ShadiNasr-EsfahaniStudent of Medicine, Student Research Committee, School of Medicine AND Isfahan Clinical Toxicology Research Center, Isfahan University of Medical Sciences, Isfahan, IranNastaranEizadi-MoodProfessor, Isfahan Clinical Toxicology Research Center, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran0000-0001-9792-8160Journal Article20171120Background: Poisoning with organophosphate (OP) compounds is common and causes many complications, including seizure. The purpose of this study was to investigate the predictor factors of seizure in patients with organophosphate poisoning.Methods: This study was performed on patients with organophosphate poisoning hospitalized from 2007 to 2015 in university referral hospital in Isfahan City, Iran. Patients' information including age, sex, seizure, time between ingestion and admission to hospital, vital signs, duration of connection to ventilator, blood glucose, and blood pH were evaluated. The different variables were compared between patients with and without seizure. Binary logistic regression was used for determining variables for prediction of seizure.Findings: 209 patients with organophosphate poisoning were evaluated during the study period. Patients’ mean age was 33.1 ± 18.4 years (range: 2-90 years). Most of the patients were men (61.2%). The prevalence of seizure in patients was 5.7%, which was more common in patients with miosis (33.3% vs. 13.7%, P = 0.040). Patients with seizure required more intubation and longer periods of ventilation (5.1 ± 3.2 vs. 0.9 ± 0.4 days, P < 0.001). There was no significant difference between patients with and without seizure with respect to other variables. 27 patients died, of whom 3 patients had seizure. None of the above variables were predictive for seizure.Conclusion: The results of this study showed that the prevalence of seizure in patients with organophosphate poisoning was 5.7%. Seizure was more common in those with miosis. Length of ventilation was more in patients with seizure.Background: Poisoning with organophosphate (OP) compounds is common and causes many complications, including seizure. The purpose of this study was to investigate the predictor factors of seizure in patients with organophosphate poisoning.Methods: This study was performed on patients with organophosphate poisoning hospitalized from 2007 to 2015 in university referral hospital in Isfahan City, Iran. Patients' information including age, sex, seizure, time between ingestion and admission to hospital, vital signs, duration of connection to ventilator, blood glucose, and blood pH were evaluated. The different variables were compared between patients with and without seizure. Binary logistic regression was used for determining variables for prediction of seizure.Findings: 209 patients with organophosphate poisoning were evaluated during the study period. Patients’ mean age was 33.1 ± 18.4 years (range: 2-90 years). Most of the patients were men (61.2%). The prevalence of seizure in patients was 5.7%, which was more common in patients with miosis (33.3% vs. 13.7%, P = 0.040). Patients with seizure required more intubation and longer periods of ventilation (5.1 ± 3.2 vs. 0.9 ± 0.4 days, P < 0.001). There was no significant difference between patients with and without seizure with respect to other variables. 27 patients died, of whom 3 patients had seizure. None of the above variables were predictive for seizure.Conclusion: The results of this study showed that the prevalence of seizure in patients with organophosphate poisoning was 5.7%. Seizure was more common in those with miosis. Length of ventilation was more in patients with seizure.https://jims.mui.ac.ir/article_15440_379d08c7a38df48c777c07ea990a3bcf.pdfIsfahan University of Medical SciencesJournal of Isfahan Medical School1027-75953545820180121Evaluation of Wound Healing and Antimicrobial Properties of Hydrogel Dressings of Starch Containing Ethanolic Extract of Propolis in the RatEvaluation of Wound Healing and Antimicrobial Properties of Hydrogel Dressings of Starch Containing Ethanolic Extract of Propolis in the Rat174417481544110.22122/jims.v35i458.9336FAAsgharEskandariniaMSc Student, Department of Biomaterials, Tissue Engineering and Nanotechnology, Student Research Committee, School of Advanced Medical Technologies, Isfahan University of Medical Sciences, Isfahan, IranMohamamdRafieniaAssociate Professor, Department of Biomaterials, Tissue Engineering and Nanotechnology, School of Advanced Medical Technologies AND Biosensor Research Center, Isfahan University of Medical Sciences, Isfahan, IranMosayebGharakhlooDepartment of Polymer Science, Iran Polymer and Petrochemical Institute, Tehran, IranSepehrNavidMSc Student, Department of Microbiology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, IranAmirhoseinKefayatGeneral Practitioner, Cancer Prevention Research Center, Isfahan University of Medical Sciences, Isfahan, IranJournal Article20171213Background: In this research, we intended to fabricate hydrogel wound dressing by solvent-casting method with combination of starch and propolis, which is suitable for wound due to their suitable properties. Current wound dressings do not have capability of protecting wound from injuries and microorganism contaminations ideally.Methods: For preparation of film, a certain amount of corn starch was mixed with deionized water and followed by the addition of glycerol in a specific ratio (4/10 dried weight of starch). The ethanolic extract of propolis was added to the aforementioned solution in ratios of 0.25, 0.5, and 1 percent. The obtained mixture was casted on polytetrafluoroethylene (PTFE) mold and their structure and features were characterized using mechanical properties, scanning electron microscope (SEM), and antimicrobial activity.Findings: The antimicrobial properties of the wound dressing showed significant improvement by increasing of propolis concentration. There was a significant difference about the rate of wound healing in group of hydrogel dressing of starch and hydroalcoholic extract of propolis compared to other group (P < 0.05).Conclusion: According to our findings, nanosilver dressing can be effective in controlling superficial wound infection.Background: In this research, we intended to fabricate hydrogel wound dressing by solvent-casting method with combination of starch and propolis, which is suitable for wound due to their suitable properties. Current wound dressings do not have capability of protecting wound from injuries and microorganism contaminations ideally.Methods: For preparation of film, a certain amount of corn starch was mixed with deionized water and followed by the addition of glycerol in a specific ratio (4/10 dried weight of starch). The ethanolic extract of propolis was added to the aforementioned solution in ratios of 0.25, 0.5, and 1 percent. The obtained mixture was casted on polytetrafluoroethylene (PTFE) mold and their structure and features were characterized using mechanical properties, scanning electron microscope (SEM), and antimicrobial activity.Findings: The antimicrobial properties of the wound dressing showed significant improvement by increasing of propolis concentration. There was a significant difference about the rate of wound healing in group of hydrogel dressing of starch and hydroalcoholic extract of propolis compared to other group (P < 0.05).Conclusion: According to our findings, nanosilver dressing can be effective in controlling superficial wound infection.https://jims.mui.ac.ir/article_15441_95ce3f8d06bd430b4ccd1e8309bf19e6.pdfIsfahan University of Medical SciencesJournal of Isfahan Medical School1027-75953545820180121Investigation of the Effect of Intravenous Selenium on the Ratio of Partial Pressure of Arterial Oxygen and Fraction of Inspired Oxygen (PaO2/FiO2) and Arterial Blood Gases in Patients under Mechanical Ventilation in Intensive Care UnitsInvestigation of the Effect of Intravenous Selenium on the Ratio of Partial Pressure of Arterial Oxygen and Fraction of Inspired Oxygen (PaO2/FiO2) and Arterial Blood Gases in Patients under Mechanical Ventilation in Intensive Care Units174917541544210.22122/jims.v35i458.8861FABabakAlikiaiiAssistant Professor, Department of Anesthesiology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran0000-0003-3236-1970OmidAghadavoudiProfessor, Anesthesiology and Critical Care Research Center, Isfahan University of Medical Sciences, Isfahan, Iran0000-0002-2251-1800HassanAlchaabiStudent of Medicine, Student Research Committee, School of Medicine, Isfahan University of Medical Sciences, Isfahan, IranJournal Article20170925Background: Because of the importance of antioxidant role of selenium as one of the components of selenoproteins, we designed this study to assess the effect of intravenous (IV) selenium with anti-inflammatory and immunomodulatory properties, on the ratio of partial pressure of arterial oxygen and fraction of inspired oxygen (PaO2/FiO2), and arterial blood gases in patients admitted to intensive care unit (ICU).Methods: In this randomized double-blind clinical-trial study, 90 patients under mechanical ventilation in intensive care units of Alzahra hospital, Isfahan, Iran, were selected and randomly divided into three groups. First group of patients received selenium 1000 µg daily; the second group received selenium 500 µg daily; and finally the third group did not received the drug as control group.Findings: There was no significant difference between the mean PaO2/FiO2 ratio in the first group (291.20 ± 28.60) with the second (291.63 ± 20.42) and the third (288.73 ± 20.77) groups (P = 0.50). The mean partial pressure of arterial oxygen was not also significantly different in the first group (95.90 ± 4.21) with the second (94.36 ± 5.18) and the third (94.46 ± 5.09) groups (P = 0.24). The average duration of extubation was not significantly different among the three groups (P = 0.16).Conclusion: Administration of intravenous selenium has no effect on the PaO2/FiO2 ratio as well as arterial blood gases, and also the duration of extubation in patients admitted to intensive care units. Furthermore, administration of intravenous selenium with no effect on respiratory parameters is not associated with hemodynamic changes in these patients.Background: Because of the importance of antioxidant role of selenium as one of the components of selenoproteins, we designed this study to assess the effect of intravenous (IV) selenium with anti-inflammatory and immunomodulatory properties, on the ratio of partial pressure of arterial oxygen and fraction of inspired oxygen (PaO2/FiO2), and arterial blood gases in patients admitted to intensive care unit (ICU).Methods: In this randomized double-blind clinical-trial study, 90 patients under mechanical ventilation in intensive care units of Alzahra hospital, Isfahan, Iran, were selected and randomly divided into three groups. First group of patients received selenium 1000 µg daily; the second group received selenium 500 µg daily; and finally the third group did not received the drug as control group.Findings: There was no significant difference between the mean PaO2/FiO2 ratio in the first group (291.20 ± 28.60) with the second (291.63 ± 20.42) and the third (288.73 ± 20.77) groups (P = 0.50). The mean partial pressure of arterial oxygen was not also significantly different in the first group (95.90 ± 4.21) with the second (94.36 ± 5.18) and the third (94.46 ± 5.09) groups (P = 0.24). The average duration of extubation was not significantly different among the three groups (P = 0.16).Conclusion: Administration of intravenous selenium has no effect on the PaO2/FiO2 ratio as well as arterial blood gases, and also the duration of extubation in patients admitted to intensive care units. Furthermore, administration of intravenous selenium with no effect on respiratory parameters is not associated with hemodynamic changes in these patients.https://jims.mui.ac.ir/article_15442_579bb1d9cafd92b8d307a8c6943dc0aa.pdfIsfahan University of Medical SciencesJournal of Isfahan Medical School1027-75953545820180121Comparison of the Effect of Resistance Training and Lavender Fragrances on Erection Function in Men during Methadone Treatment of Opioid DependenceComparison of the Effect of Resistance Training and Lavender Fragrances on Erection Function in Men during Methadone Treatment of Opioid Dependence175517611544310.22122/jims.v35i458.8921FAAhmadrezaKiyani-SelmiDepartment of Physical Education and Sport Sciences, School of Physical Education and Sport Sciences, Isfahan (Khorasgan) Branch, Islamic Azad University, Isfahan, IranRokhsarehBadamiAssociate Professor, Department of Physical Education and Sport Sciences, School of Physical Education and Sport Sciences, Isfahan (Khorasgan) Branch, Islamic Azad University, Isfahan, Iran0000-0002-4507-0382FarzanehTaghianAssociate Professor, Department of Physical Education and Sport Sciences, School of Physical Education and Sport Sciences, Isfahan (Khorasgan) Branch, Islamic Azad University, Isfahan, Iran0000-0001-9531-2952Journal Article20171010Background: Methadone has long been regarded as an effective treatment for opioid dependence. However, many patients discontinue maintenance therapy because of its side effects, with one of the most common ones is erection dysfunction. This study aimed to determine and compare the effect of resistance training and lavender fragrances on erection function in men during methadone treatment of opioid dependence.Methods: This was an experimental study with pretest-posttest design and control group. The participants of the study were 50 married men aged between 30 and 45 years, who had gone to addiction treatment centers two week before. They were selected via convenience sampling method and were allocated to four groups of resistance training, lavender, combination (resistance training and lavender), and control after being matched on the basis of age and history of addiction. Resilient and combined training group participated in resistance training sessions for 24 sessions (8 weeks, 3 sessions a week). Lavender and combination group smelled lavender for 21 sessions of 20 minutes. Before and after the intervention, the data were collected using the erectile function of men questionnaire. Data were analyzed using ANCOVA test.Findings: All three types of intervention; resistance training (P = 0.002), lavender (P < 0.001), and combination group (P < 0.001) improved erection function significantly. In addition, using lavender fragrances had a better effect on erection function compared to resistance training (P = 0.003).Conclusion: It is recommended to use resistance training and fragrances to improve sexual function in men during methadone treatment of opioid dependence.Background: Methadone has long been regarded as an effective treatment for opioid dependence. However, many patients discontinue maintenance therapy because of its side effects, with one of the most common ones is erection dysfunction. This study aimed to determine and compare the effect of resistance training and lavender fragrances on erection function in men during methadone treatment of opioid dependence.Methods: This was an experimental study with pretest-posttest design and control group. The participants of the study were 50 married men aged between 30 and 45 years, who had gone to addiction treatment centers two week before. They were selected via convenience sampling method and were allocated to four groups of resistance training, lavender, combination (resistance training and lavender), and control after being matched on the basis of age and history of addiction. Resilient and combined training group participated in resistance training sessions for 24 sessions (8 weeks, 3 sessions a week). Lavender and combination group smelled lavender for 21 sessions of 20 minutes. Before and after the intervention, the data were collected using the erectile function of men questionnaire. Data were analyzed using ANCOVA test.Findings: All three types of intervention; resistance training (P = 0.002), lavender (P < 0.001), and combination group (P < 0.001) improved erection function significantly. In addition, using lavender fragrances had a better effect on erection function compared to resistance training (P = 0.003).Conclusion: It is recommended to use resistance training and fragrances to improve sexual function in men during methadone treatment of opioid dependence.https://jims.mui.ac.ir/article_15443_cd081ee8c70ba7996043bf45c9d42ebf.pdf