نوع مقاله : مقاله های پژوهشی
نویسندگان
1 استادیار، مرکز تحقیقات گیاهان دارویی، دانشگاه علوم پزشکی یاسوج، یاسوج، ایران
2 کارشناس ارشد، گروه فیزیولوژی، دانشگاه آزاد اسلامی، واحد علوم و تحقیقات فارس، شیراز، ایران
3 دانشیار، مرکز تحقیقات سلولی و مولکولی، دانشگاه علوم پزشکی یاسوج، یاسوج، ایران
چکیده
کلیدواژهها
عنوان مقاله [English]
نویسندگان [English]
Background: It has been shown that reproductive system is affected by diabetes mellitus. The aim of this research was assessing the effect of Capparis spinosa on reproductive parameters and the rate of testosterone after induction of diabetes in rats.Methods: 48 Wistar rats (200-250 g) were divided into 6 groups of 8. The shame and diabetic control groups received distilled water. The shame and two diabetic treatment groups received 20, 20 and 30 mg/kg hydroalcohoic extract of Capparis spinosa, respectively. The sixth group received 100 mg/kg of vitamin E. All groups treated for 21 days; then, the rate of testosterone hormone and qualities of sperm were measured.Findings: The mean values of fast mobility and normal morphology of sperm increased significantly (64.25 ± 15.31 and 70.38 ± 19.78 percent, respectively) in diabetic treatment rats received 30 mg/kg of Capparis spinosa compared to control diabetic group. Although, the rate of testosterone increased in diabetic treatment groups, but was not significant.Conclusion: The hydroalcohoic extract of Capparis spinosa could improve the reproductive parameters in diabetic rats.
کلیدواژهها [English]