بررسی ارتباط ترومبوآمبولی ریوی با شدت درگیری پارانشیم ریه در بیماران مبتلا به کووید-19 تحت سی تی آنژیوگرافی پولمونر

نوع مقاله : Original Article(s)

نویسندگان

1 دستیار تخصصی، گروه رادیولوژی، بیمارستان گلستان، دانشگاه علوم پزشکی جندی شاپور اهواز، اهواز، ایران

2 استادیار، گروه رادیولوژی، بیمارستان گلستان، دانشگاه علوم پزشکی جندی شاپور اهواز، اهواز، ایران

چکیده

مقاله پژوهشی




مقدمه: ترومبو آمبولی ریه (Pulmonary thromboembolism) PTE یکی از عواقب شناخته شده‌ی عفونت کووید-19 است. هدف ما ارزیابی ارتباط ترومبوآمبولی ریوی با شدت درگیری پارانشیمال در بیماران مبتلا به عفونت کووید-19 می‌باشد.
روش‌ها: در این مطالعه‌ی گذشته‌نگر، 238 بیمار کووید-19 را که بین فروردین‌ماه تا مهر‌ماه 1400 تحت CT آنژیوگرافی ریه قرار گرفتند، ارزیابی کردیم. بیماری‌های زمینه‌ای، پارامترهای آزمایشگاهی، پیامد بالینی و ترومبوز وریدی بیماران ثبت شد. یک متخصص رادیولوژی سی‌تی آنژیوگرافی قفسه‌ی سینه و شدت آمبولی را با استفاده از سیستم Mastora ارزیابی کرد. عوامل مرتبط با PTE و شدت انسداد شریانی با استفاده از تجزیه و تحلیل آماری مورد ارزیابی قرار گرفتند.
یافته‌ها: میانگین سنی بیماران 16/4 ± 53 بود. 47/1 درصد (112) از بیماران زن و 51/7 درصد (123) مرد بوده‌اند. میزان درگیری ریه در بیماران، تحت تأثیر سن قرار نگرفت (0/4 = P). در 26/5 درصد از بیماران، PTE مثبت بود که توزیع تقریباً یکسانی در هر دو جنس داشت و تفاوتی بین بیماران زن و مرد دیده نشد. سن تأثیری در بروز PTE نداشت (0/7 = P). شدت درگیری ریه به طور میانگین در بیماران 24/1 ± 56 درصد بود که این میزان به طور قابل توجهی در مردان بالاتر بود (0/007 = P). همچنین، در بیمارانی که دچار PTE بوده‌اند میزان درگیری ریه به طور معنی‌داری بیشتر بود (0/02 = P).
نتیجه‌گیری: شدت درگیری ریه ناشی از ابتلا به کووید-19 با جنسیت ارتباط دارد و شدت آن در مردان بیشتر از زنان می‌باشد. بروز PTE در بیماران با درگیری ریوی شدیدتر بیشتر بود.

تازه های تحقیق

سمیرا خلیلی:  Google Scholar

مژگان صامت زاده: PubMed, Google Scholar

محمد قاسم حنفی: Google Scholar

کلیدواژه‌ها

موضوعات

عنوان مقاله [English]

Investigating the Relationship between Pulmonary Thromboembolism and the Severity of Parenchymal Involvement in Patients with COVID-19 Undergoing CT Pulmonary Angiography

نویسندگان [English]

  • Samira Khalili 1
  • Zahra Fazelinezhad 2
  • Mohammad Ghasem Hanafi 2
  • Mojgan Sametzadeh 2
1 Resident Assistant, Department of Radiology, Golestan Hospital, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
2 Assistant Professor, Department of Radiology, Golestan Hospital, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
چکیده [English]

Background: Pulmonary thromboembolism (PTE) is one of the well-known consequences of COVID-19 infection. We aim to evaluate the relationship between pulmonary thromboembolism and the severity of parenchymal involvement in patients with COVID-19 infection.
Methods: In this retrospective study, we evaluated 238 COVID-19 patients who underwent CT angiography of the lung between April and October 2021. Background diseases, laboratory parameters, clinical outcomes, and venous thrombosis of the patients were recorded. A radiologist assessed the severity of pulmonary thromboembolism on pulmonary CT angiography using the Mastora system. Factors associated with PTE and severity of arterial occlusion were evaluated using statistical analysis. A P-value of 0.05 was considered significant.
Findings: The average age of the patients was 53 ± 16.4. 47.1% (112) of patients were female and 51.7% (123) were male. The rate of lung involvement in patients was not affected by age (P = 0.4). In 26.5% of patients, PTE was positive, which had almost the same distribution in both sexes, and no difference was seen between male and female patients. The incidence of PTE was not affected by the age of the patients (P = 0.7). The severity of lung involvement was an average of 56% ± 24.1 in patients, which was significantly higher in men (P = 0.007). Also, lung involvement was significantly higher in patients who had PTE (P = 0.02).
Conclusion: The severity of lung involvement following COVID-19 infection is higher in men than women. The incidence of PTE is higher in patients with more severe pulmonary involvement.

کلیدواژه‌ها [English]

  • COVID-19؛ Thromboembolism؛ CT Scan
  • Angiography

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مجله دانشکده پزشکی اصفهان
دوره 42، شماره 760
هفته 4، اردیبهشت
فروردین و اردیبهشت 1403
صفحه 202-208

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  • تاریخ دریافت: 25 اردیبهشت 1402
  • تاریخ پذیرش: 10 تیر 1403

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