بررسی ارتباط چربی‌های رژیم غذایی با شاخص‌های سندرم متابولیک در بیماران مبتلا به دیابت نوع 2

نوع مقاله : مقاله های پژوهشی

نویسندگان

1 دانشجوی کارشناسی ارشد، مرکز تحقیقات امنیت غذایی و گروه تغذیه‌ی بالینی، دانشکده‌ی تغذیه و علوم غذایی و کمیته‌ی تحقیقات دانشجویی، دانشگاه علوم پزشکی اصفهان، اصفهان، ایران

2 استادیار، مرکز تحقیقات امنیت غذایی و گروه تغذیه‌ی بالینی، دانشکده‌ی تغذیه و علوم غذایی، دانشگاه علوم پزشکی اصفهان، اصفهان، ایران

3 دانشیار، گروه آمار و اپیدمیولوژی، دانشکده‌ی بهداشت، دانشگاه علوم پزشکی اصفهان، اصفهان، ایران

4 استادیار، مرکز تحقیقات امنیت غذایی و گروه تغذیه‌ی جامعه، دانشکده‌ی تغذیه و علوم غذایی، دانشگاه علوم پزشکی اصفهان، اصفهان، ایران

5 فوریت‌های پزشکی، دانشگاه علوم پزشکی اصفهان، اصفهان، ایران

چکیده

قدمه: سندرم متابولیک، مجموعه‌ای از اختلالات متابولیک است که شیوع آن در بیماران مبتلا به دیابت در حال افزایش است. کیفیت چربی‌های رژیم غذایی بر روی شاخص‌های سندرم متابولیک اثر دارد. هدف از مطالعه‌ی حاضر، بررسی ارتباط اسیدهای چرب رژیم غذایی با شاخص‌های سندرم متابولیک در بیماران مبتلا به دیابت نوع 2 بود.روش‌ها: مطالعه‌ی حاضر، از نوع مطالعات مقطعی بود و بر روی 300 نفر از بیماران مبتلا به دیابت نوع 2 انجام شد. رژیم غذایی افراد شرکت کننده با پرسش‌نامه‌ی بسامد خوراک ارزیابی شد. تحلیل داده‌های غذایی با نرم‌افزار Nutritionist4 و محاسبات آماری با نرم‌افزار SPSS انجام شد.یافته‌ها: 6/69 درصد از بیماران، مبتلا به سندرم متابولیک بودند. بعد از تعدیل عوامل مخدوشگر، ارتباط معکوس معنی‌داری بین اسیدهای چرب امگا 3 با فشار خون سیستول (010/0 = P) و دیاستول (002/0 = P) مشاهده شد. همچنین، رابطه‌ی مستقیم معنی‌داری بین اسیدهای چرب با یک باند دوگانه با قند خون ناشتا (006/0 = P) و اسید چرب امگا 3 با تری‌گلیسیرید (010/0 = P) مشاهده شد.نتیجه‌گیری: بر اساس نتایج مطالعه، اسیدهای چرب امگا 3 با کاهش فشار خون افراد مبتلا به دیابت نوع 2، ارتباط دارند و همچنین ارتباط مستقیمی بین مصرف اسیدهای چرب با یک باند دوگانه با قند خون ناشتا و اسیدهای چرب امگا 3 با تری‌گلیسیرید مشاهده شد، اما برای تأیید نتایج، مطالعات آینده‌نگر بیشتری نیاز است.

کلیدواژه‌ها

عنوان مقاله [English]

Association of Dietary Fatty Acids with Metabolic Syndrome Indices in Patients with Type 2 Diabetes

نویسندگان [English]

  • Nafiseh Sbohani 1
  • Mohammad Hasan Entezari 2
  • Awat Feizi 3
  • Gholamreza Asgari 4
  • Jamal Reiesi 5
1 MSc Student. Food Security Research Center AND Department of Community Nutrition, School of Nutrition and Food Sciences AND Student Research Committee, Isfahan University of Medical Sciences, Isfahan, Iran
2 Assistant Professor, Food Security Research Center AND Department of Clinical Nutrition, School of Nutrition and Food Sciences, Isfahan University of Medical Sciences, Isfahan, Iran
3 Associate Professor, Department of Epidemiology, School of Health, Isfahan University of Medical Sciences, Isfahan, Iran
4 Assistant Professor, Food Security Research Center AND Department of Community Nutrition, School of Nutrition and Food Sciences, Isfahan University of Medical Sciences, Isfahan, Iran
5 Emergency Medical Service, Isfahan University of Medical Sciences, Isfahan, Iran
چکیده [English]

Background: The metabolic syndrome includes several metabolic disorders and its incidence is increasing among diabetic patients. Types of dietary fats have been related to components of the metabolic syndrome. So this study aimed to investigate the association between dietary fatty acids with metabolic syndrome indices in patients with type 2 diabetes.Methods: This cross-sectional study was conducted on 300 patients with type 2 diabetes. Dietary intake was assessed using a validated Food Frequency Questionnaire. Nutritionist 4 Software was employed for analysis of dietary variables and SPSS software was used for statistical analysis.Findings: 69.6% 0f patients were diagnosed with metabolic syndrome. After adjustment of the confounder factors a significant negative correlation was observed between omega3 with systole blood pressure (P = 0.01) and diastole blood pressure (P = 0.002). Also significant positive correlation was observed between mono unsaturated fatty acids with fasting blood sugar (P = 0. 006) and omega3 with triglyceride (P = 0.01).Conclusion: According to the study, omega3 fatty acids are associated with a lower blood pressure in people with type 2 diabetes. Also, we observed positive correlation between mono unsaturated fatty acids with fasting blood sugar and omega3 with triglyceride. But, further prospective investigations are needed to confirm our results.

کلیدواژه‌ها [English]

  • Fatty acids
  • Diet
  • Metabolic Syndrome
  • Diabetes

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مجله دانشکده پزشکی اصفهان
دوره 34، شماره 383 - شماره پیاپی 383
مرداد و شهریور 1395
صفحه 563-571

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سابقه مقاله

  • تاریخ دریافت: 03 آذر 1394
  • تاریخ بازنگری: 11 آبان 1403
  • تاریخ پذیرش: 17 فروردین 1401

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