میزان بقای کوتاه مدت انفارکتوس قلبی حاد در بیماران مسن

نوع مقاله : مقاله های پژوهشی

نویسندگان

1 اپیدمیولوژیست، دانشگاه علوم پزشکی اصفهان، اصفهان و دانشجوی دکتری، گروه آمار زیستی و اپیدمیولوژی، دانشکده‌ی بهداشت، دانشگاه علوم پزشکی تهران، تهران، ایران

2 استاد، مرکز تحقیقات قلب و عروق، پژوهشکده‌ی قلب و عروق اصفهان، دانشگاه علوم پزشکی اصفهان، اصفهان، ایران

3 دانشیار، مرکز تحقیقات غدد (فیروزگر) انستیتو غدد درون‌ریز و متابولیسم (پردیس همت)، دانشگاه علوم پزشکی ایران، تهران، ایران

4 واحد سورویلانس، مرکز تحقیقات فشار خون، پژوهشکده‌ی قلب و عروق، دانشگاه علوم پزشکی اصفهان، اصفهان، ایران

5 دانشیار، مرکز تحقیقات آسیب‌شناسی و سرطان، دانشگاه علوم پزشکی ایران، تهران، ایران

چکیده

مقدمه: بیماری‌های قلبی- عروقی اولین عامل مرگ و میر و مهم‌ترین عامل بستری در بیمارستان در افراد مسن می‌باشد. بنابراین، هدف این مطالعه تعیین میزان بقای کوتاه مدت از سکته‌ی قلبی حاد در بین افراد سالمند بر اساس سن و جنس می‌باشد.روش‌ها: این مطالعه یک مطالعه‌ی هم‌گروهی مبتنی بر بیمارستان بود که در طی یک دوره‌ی 10 ساله، تمامی بیماران مبتلا به سکته‌ی قلبی حاد با سن بالاتر از 65 سال ساکن اصفهان و نجف‌آباد را مورد بررسی قرار داد. جهت تعیین و مقایسه‌ی میانگین سن بیماران بر اساس گروه‌بندی‌های مختلف، از آزمون آماری t و جهت تعیین میزان بقای بیماران از آزمون آماری Kaplan-Meier و آزمون Log-rank استفاده شد.یافته‌ها: میزان بقای کلی 28 روزه‌ی بیماران با سن 65 سال و بالاتر، 5/85 درصد بود که این میزان برای مردان برابر با 7/86 درصد و برای زنان برابر با 5/83 درصد بود (001/0 ≥ P). میزان بقا در گروه‌های سنی 74-65 سال، 84-75 سال و 85 سال و بالاتر، به ترتیب برابر با 7/88، 3/81 و 6/75 درصد بود که این اختلاف از نظر آماری معنی‌دار بود (001/0 ≥ P).نتیجه‌گیری: میزان بقا در زنان از مردان کمتر است و با افزایش سن نیز این میزان به طور مستمر کاهش می‌یابد. بنابراین توجه به زنان و به خصوص افراد با میانگین سنی بالاتر، در ارایه‌ی خدمات درمانی با توجه به خطر بیشتر مرگ و میر در آن‌ها، می‌تواند در بهبود پیامد بیماری مؤثر باشد. 

کلیدواژه‌ها

عنوان مقاله [English]

Short-Time Survival Rate of Acute Myocardial Infarction in Elderly Patients in Isfahan City, Iran

نویسندگان [English]

  • Abdollah Mohammadian-Hafshejani 1
  • Nazal Sarrafzadegan 2
  • Hamid Reza Baradaran 3
  • Shidokht Hosseini 4
  • Mohsen Asadi-Lari 5
1 Epidemiologist, Isfahan University of Medical Sciences, Isfahan AND PhD Candidate, Department of Biostatistics and Epidemiology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
2 Professor, Cardiovascular Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
3 Associate Professor, Research Institute of Endocrine Sciences, Iran University of Medical Sciences, Tehran, Iran
4 Hypertension Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
5 Associate Professor, Oncopathology Research Centre, Iran University of Medical Sciences, Tehran, Iran
چکیده [English]

Background: Cardiovascular disease is the first cause of mortality and hospital admission in elderly patients. The purpose of this study was to determine the short-term survival rates of acute myocardial infarction among elderly patients by age and sex.Methods: This was cohort-hospital study based on hospital admission in a 10-years period, that contained all elderly patients with acute myocardial infarction (AMI) aged equivalent or more than 65 years in Isfahan and Najaf Abad, Iran. To determine and compare the mean age, we used t-test and for survival rate Kaplan-Meier method and log-rank test were used.Findings: The overall 28-day survival rate for patients aged 65 years and more was 85.5%, against a 86.7% rate for men and 83.5% for women (P < 0.001). Survival rate in the age groups of 65 to 74, 75 to 84 and 85 and more years were 88.7%, 81.3%, 75.6%, respectively, with statistically significant difference (P < 0.001).Conclusion: Short-term survival rates of acute myocardial infarction is lower in elderly women than men; and in two genders, with increasing age, the rate continuously decreases. So, paying attention to women, especially older, due to higher risk of death, could be effective in improving outcomes.

کلیدواژه‌ها [English]

  • Acute myocardial infarction
  • Short-term survival
  • Kaplan-Meier
  • Elderly

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مجله دانشکده پزشکی اصفهان
دوره 32، شماره 303 - شماره پیاپی 303
مهر و آبان 1393
صفحه 1585-1593

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سابقه مقاله

  • تاریخ دریافت: 18 بهمن 1392
  • تاریخ بازنگری: 12 آبان 1403
  • تاریخ پذیرش: 17 فروردین 1401

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