The Effects of Main Semen Parameters on Intra-Uterine Insemination (IUI) Outcome

Document Type : Original Article (s)

Authors

1 Associate Professor, Department of Anatomical Sciences, School of Medicine, Isfahan University of Medical Sciences AND Infertility Laboratory, Shahid Beheshti Hospital, Isfahan, Iran

2 Student of Medicine, School of Medicine AND Student Research Committee, Isfahan University of Medical Sciences, Isfahan, Iran

3 Epidemiologist, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

4 Infertility Laboratory, Shahid Beheshti Hospital, Isfahan, Iran

Abstract

Background: Infertility is common among couples of childbearing age. Approximately, half of known causes of primary infertility are attributable to male factor and the etiology of male factors infertility is poorly understood. While some individuals may be genetically predisposed to be sub-fertile, there are major epigenetic factors implicated as potential causes of male infertility. Semen characteristics such as morphology, concentration and motility have positive effect of infertility. One of the most prevalent methods for solving this problem is Intra-Uterine Insemination (IUI) and the aim of this study was determining the effect semen characteristics on IUI outcomes.Methods: This cross sectional study was done in Shahid Beheshti hospital (Isfahan, Iran) during March to September 2012. 80 samples of semen of infertile men were selected and analyzed by semen analysis and semen processing methods. Semen characteristics such as physical characteristics and motility were recorded and analyzed.Findings: Fertility in 16 cases (20%) was success and in 64 (80%) was unsuccess. Semen characteristics including volume, concentration and motility was not statistically different between these two groups.Conclusion: According to results of this study, except semen characteristics, some other factors such as technique of sperm injection, medical instruments and patient factors may have a role in unfertility. Thus, this factors and related protocols mast be revised and couple education mast be done before sperm injection.

Keywords

References

  1. Gurunath S, Pandian Z, Anderson RA, Bhattacharya S. Defining infertility--a systematic review of prevalence studies. Hum Reprod Update 2011; 17(5): 575-88.
  2. Hwang K, Walters RC, Lipshultz LI. Contemporary concepts in the evaluation and management of male infertility. Nat Rev Urol 2011; 8(2): 86-94.
  3. Dhont N, Luchters S, Muvunyi C, Vyankandondera J, De NL, Temmerman M, et al. The risk factor profile of women with secondary infertility: an unmatched case-control study in Kigali, Rwanda. BMC Womens Health 2011; 11: 32.
  4. Jequier AM. Clinical andrology-still a major problem in the treatment of infertility. Hum Reprod 2004; 19(6): 1245-9.
  5. Cooper TG, Noonan E, von Eckardstein S, Auger J, Baker HW, Behre HM, et al. World Health Organization reference values for human semen characteristics. Hum Reprod Update 2010; 16(3): 231-45.
  6. Eliasson R. Semen analysis with regard to sperm number, sperm morphology and functional aspects. Asian J Androl 2010; 12(1): 26-32.
  7. Elia J, Imbrogno N, Delfino M, Mazzilli R, Rossi T, Mazzilli F. The Importance of the Sperm Motility Classes - Future Directions. The Open Andrology Journal 2010; 2: 42-3.
  8. Yousefi B, Azargon A. Predictive factors of intrauterine insemination success of women with infertility over 10 years. J Pak Med Assoc 2011; 61(2): 165-8.
  9. Akl LD, Oliveira JB, Petersen CG, Mauri AL, Silva LF, Massaro FC, et al. Efficacy of the motile sperm organelle morphology examination (MSOME) in predicting pregnancy after intrauterine insemination. Reprod Biol Endocrinol 2011; 9: 120.
  10. Oyeyipo IP, Raji Y, Emikpe BO, Bolarinwa AF. Effects of nicotine on sperm characteristics and fertility profile in adult male rats: a possible role of cessation. J Reprod Infertil 2011; 12(3): 201-7.
  11. Obidi J. Effects of seasen on semen characteristiand fertility of shikabrown breeder cocks [Online]. [cited 2013]; Available from: URL: http://kubanni.abu.edu.ng:8080/jspui/handle/123456789/3053
Journal of Isfahan Medical School
Volume 31, Issue 258 - Serial Number 258
September and October 2013
Pages 1723-1734

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History

  • Receive Date: 03 October 2013
  • Revise Date:
  • Accept Date: 06 April 2022

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