Optimal b-Value in Diffusion Weighted Imaging for Detection Active Multiple Sclerosis Plaque, Using Contrast Enhancement Imaging

Document Type : Original Article (s)

10.22122/jims.v39i609.12913

Abstract

Background: Multiple sclerosis (MS) is an acute and autoimmune disease that causes inflammation and destruction of myelin in the central nervous system. In this study, the diffusion sequence with different values of
b-value was used to determine its optimal value for detection of active plaques.
Methods: This cross-sectional study was performed on 90 patients with MS basede on Mc Donald's criteria, referred to the Shafa Imaging Center, Isfahan, Iran. The locations of the plaques and their number were recorded by the radiologist in the relevant checklist. Imaging was performed using the Siemens Avanto system, 1.5 Tesla, with of a standard head coil.
Findings: Diffusion weighted images (DWI) with low b-values had a direct and significant relationship with contrast enhancement (CE) method in determining active plaques (P = 0.005). Images with a b-value of 500 had the highest sensitivity (75%) and sensitivity (87.3%) in detecting active plaques.
Conclusion: The results showed that the DWI with the 1.5 Tesla had the ability to distinguish active and inactive plates, because DWI images with low b-values had a direct and significant relationship with CE method in determining active plaques.

Keywords

References

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Journal of Isfahan Medical School
Volume 39, Issue 609
2021
Pages 1-5

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History

  • Receive Date: 31 March 2022
  • Accept Date: 31 March 2022

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