The Value of Intrarenal Resistive Index in Different Stages of Diabetic Nephropathy

Document Type : Original Article(s)

Authors

1 Assistant Professor, Department of Radiology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.

2 Associate Professor, Department of Radiology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.

3 Resident, Department of Radiology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.

Abstract

Background: The renal resistive index (RI), measured using doppler ultrasound, reflects intrarenal vascular resistance. We evaluated the relationship between RI with nephropathy in patients with diabetic mellitus.Methods: This study was done in Al-Zahra hospital in Isfahan. Fifty seven patients with diabetes mellitus in 3 groups (stage I, II and III of nephropathy) were compared with 19 patients in control group. The patients with renal artery stenosis or severe renal failure were excluded from the study.Finding: The mean age was 56.42 ± 10.45 years in patients. RI was 59.8 ± 2.2 percent in patients in stage I of nephropathy and in stage II and III of nephropathy it was 61.4 ± 5.8 and 82.4 ± 11.1 percent respectively. RI in control group was 63.1±5.6 percent. The RI in diabetic patients in stage III was significantly higher than other groups (P < 0.001).Conclusion: The results suggest that increased RI of the renal arteries can be more useful in patients in stage III of diabetic nephropathy. 

Keywords

References

  1. Walker JD, Viberti GC. Aetiology and pathogenesis of diabetic nephropathy: clues from early functional abnormalities. In: Pickup JC, Williams G, Editors. Textbook of diabetes. Oxford: Blackwell Science; 2003. p. 657-70.
  2. Haiser M, Gumele V, Rocq B, Chapoutot J, Ory JP, Sol F. Renal Vascular, Normal and pathological aspects. Ann Radiology 2004; 44(4): 237-47.
  3. Ellis JH. Renal Vascular disease; an epidemio-logic study, complication and treatment. Prilozi 2005; 38(2): 296-302.
  4. Breyer JA. Diabetic nephropathy in insulin-dependent patients. Am J Kidney Dis 1992; 20(6): 533-47.
  5. Hostetter TH. Diabetic nephropathy. In: Brenner BM, Rector FC, Editors. The Kidney. 8th ed. Philadelphia: WB. Saunders; 2006. p. 1377-402.
  6. Brkljacic B, Mrzljak V, Drinkovic I, Soldo D, Sabljar-Matovinovic M, Hebrang A. Renal vascular resistance in diabetic nephropathy: duplex Doppler US evaluation. Radiology 1994; 192(2): 549-54.
  7. Soldo D, Brkljacic B, Bozikov V, Drinkovic I, Hauser M. Diabetic nephropathy. Comparison of conventional and duplex Doppler ultrasonographic findings. Acta Radiol 1997; 38(2): 296-302.
  8. Ohta Y, Fujii K, Arima H, Matsumura K, Tsuchihashi T, Tokumoto M, et al. Increased renal resistive index in atherosclerosis and diabetic nephropathy assessed by Doppler sonography. J Hypertens 2005; 23(10): 1905-11.
  9. Ishimura E, Nishizawa Y, Kawagishi T, Okuno Y, Kogawa K, Fukumoto S, et al. Intrarenal he-modynamic abnormalities in diabetic nephropathy measured by duplex Doppler sonography. Kidney Int 1997; 51(6): 1920-7.
  10. Sari A, Dinc H, Zibandeh A, Telatar M, Gumele HR. Value of resistive index in patients with clinical diabetic nephropathy. Invest Radiol 1999; 34(11): 718-21.
Journal of Isfahan Medical School
Volume 28, Issue 117 - Serial Number 117
November and December 2011
Pages 1168-1172

Files

History

  • Receive Date: 19 March 2011
  • Revise Date: 01 November 2024
  • Accept Date: 06 April 2022

Share

How to cite

Statistics