Impact of Cranberry Juice Enriched With Omega-3 and Their Individual Consumption Adjunct with Nonsurgical Periodontal Treatment on Glycemic Control and Lipid Profile in Patients with Diabetes Mellitus and Periodontal Disease

Document Type : مقاله کوتاه

Authors

1 Assistant Professor, Nutrition and Metabolic Diseases Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran

2 MSc Student, Department of Nutrition, School of Paramedicine, Ahvaz Jundishapur University of Medical Sciences, Iran

3 Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran

4 Assistant Professor, Department of Periodontology, School of Dentistry , Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran

5 Assistant Professor, Department of Endocrinology, Health Research Institute, Diabetes Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran

6 Assistant Professor, Department of Biostatistics, School of Public Health AND Social Determinants of Research Center Health, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran

7 Assistant Professor, Department of Nutrition, School of Nutrition and Food Sciences, Isfahan University of Medical Sciences, Isfahan, Iran

Abstract

Background: Periodontal disease, a common widespread chronic disease, is considered as an important complication in diabetes. The aim of this study was to evaluate the effects of cranberry juice enriched with omega-3 and their individual consumption on glycemic control and lipid profile in patients with diabetes mellitus and periodontal disease.Methods: In this randomized clinical trial study, 41 patients with diabetes mellitus and chronic adult periodontal disease were randomly assigned to one group of control (n = 12) and three groups of intervention receiving omega-3 (n = 10), cranberry juice (n = 9), and cranberry juice enriched with omega-3 (n = 10) for 8 weeks. Nonsurgical periodontal therapy was provided for all the patients during the study. Fasting blood glucose, glycosylated hemoglobin A, and lipid profile were measured at baseline and at the end of the study.Findings: There was significant reduction in glycosylated hemoglobin A observed in intervention groups of receiving omega-3 (11%, P = 0.017) and cranberry enriched with omega-3 (7%, P = 0.014). The intervention group receiving omega-3 had significantly lower glycosylated hemoglobin A compared with control group. Furthermore, the intervention group receiving cranberry juice enriched with omega-3 had significantly higher high-density lipoprotein cholesterol (HDL-C) than the other intervention groups. There were no significant differences found in fasting blood sugar (FBS), triglyceride (TG), total cholesterol and Low-density lipoprotein cholesterol (LDL-C) between and within the groups.Conclusion: It is suggested that consumption of cranberry juice enriched with omega-3 as a nutritional approach in adjunct with nonsurgical periodontal therapy may help to improve glycemic control and lipid profile in patients with diabetes mellitus and periodontal disease.

Keywords

References

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Journal of Isfahan Medical School
Volume 35, Issue 440 - Serial Number 440
May and June 2017
Pages 919-926

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History

  • Receive Date: 06 May 2014
  • Revise Date: 01 November 2024
  • Accept Date: 06 April 2022

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