جایگاه هورمسیس پرتوی در حیطه‌ی رادیولوژی: مقاله مروری

نوع مقاله : مقاله مروری

نویسندگان

1 دانشجو، گروه تکنولوژی پرتوشناسی، کمیته‌ی تحقیقات دانشجویی، دانشکده‌ی پیراپزشکی، دانشگاه علوم پزشکی اصفهان، اصفهان، ایران

2 دانشیار، گروه تکنولوژی پرتوشناسی، دانشکده‌ی پیراپزشکی، دانشگاه علوم پزشکی اصفهان، اصفهان، ایران

چکیده

مقدمه: بر اساس فرضیه‌ی هورمسیس پرتویی، تابش پرتوی یونیزان با دز کم نه تنها خطرناک نیست، بلکه حتی تعداد سرطان را در جامعه‌ی مورد تابش، به کمتر از حد خودبه‌خودی می‌رساند. هدف از انجام این مطالعه، بررسی جایگاه هورمسیس پرتویی در حیطه‌ی رادیولوژی بودروش‌ها: با استفاده از پایگاه‌های اطلاعاتی PubMed، Proquest، Scopus، Science direct، Google scholar و Web of science، بر اساس کلید واژه‌های Ionizing radiation، Dose response، Hormesis، Low dose radiation، Radiology، Radiation worker و Patient، مطالعات مختلف در بازه‌ی زمانی 2019-1990 جستجو شدند.یافته‌ها: در مراحل اولیه‌ی جستجو، تعداد 1230 مطالعه در پایگاه‌های اطلاعاتی یافت شدند. با بررسی عناوین و خلاصه‌ی مقالات، در نهایت تعداد 38 مقاله‌ی مرتبط با موضوع به دست آمد. با بررسی دقیق چهار حوزه شامل حوزه‌ی ژنتیک با 14 مقاله، حوزه‌ی سلولی با 16 مقاله، حوزه‌ی حیوانی با 2 مقاله و حوزه‌ی انسانی با 6 مقاله طبقه‌بندی شدند.نتیجه‌گیری: اثر هورمسیس پرتویی در برخی از مطالعات رد و در برخی تأیید شده است، اما در شرایط تابشی مشابه با آن چه در حیطه‌ی رادیولوژی برای بیماران و پرتوکاران وجود دارد، به اثبات نرسیده است. برای تأیید و یا عدم تأیید نهایی این مدل پاسخ دز در حیطه‌ی رادیولوژی، لازم است مطالعات دقیقی در شرایط تابش مشابه با آزمون‌های مختلف رادیولوژی از نظر نوع پرتو، انرژی پرتو، دز و آهنگ دز تابشی انجام شود.

کلیدواژه‌ها

عنوان مقاله [English]

Radiation Hormesis in the Scope of Radiology: A Review Article

نویسندگان [English]

  • Mahsa Hooshangi 1
  • Ali Chaparian 2
1 Student, Department of Technology of Radiology, Student Research Committee, School of Paramedicine, Isfahan University of Medical Sciences, Isfahan, Iran
2 Associate Professor, Department of Technology of Radiology, School of Paramedicine, Isfahan University of Medical Sciences, Isfahan, Iran
چکیده [English]

Background: According to the radiation hormesis hypothesis, low-dose ionizing radiation is not only dangerous, but also can even reduce the number of cancers in the irradiated community. The aim of this study was to evaluate radiation hormesis in the field of radiology.Methods: The search was conducted through Science Direct, Scopus, PubMed, EMBASE, Google Scholar, and Web of science databases using the keywords of Ionizing radiation, Dose response, Hormesis, Low-dose radiation, Radiology, Radiation worker, and Patient in the period of 1990-2019.Findings: In the early stages of the search, 1230 studies were found in databases. Finally, by reviewing the titles and abstracts of the articles, there were 38 articles related to the research topic. After careful consideration, four main areas were categorized including genetics area with 14 articles, cell area with 16 articles, animal area with 2 articles, and human area with 6 articles.Conclusion: The effect of radiation hormesis has been rejected in some studies and confirmed in some others; but has not been demonstrated in radiation conditions similar to those found in radiology for patients and radiation workers. To confirm or disapprove this dose response model, detailed studies should be performed on radiation conditions such as different radiological tests in terms of beam type, beam energy, dose, and radiation dose rate.

کلیدواژه‌ها [English]

  • Radiation
  • Hormesis
  • Radiology

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مجله دانشکده پزشکی اصفهان
دوره 38، شماره 562 - شماره پیاپی 562
فروردین و اردیبهشت 1399
صفحه 39-48

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سابقه مقاله

  • تاریخ دریافت: 29 شهریور 1398
  • تاریخ بازنگری: 11 آبان 1403
  • تاریخ پذیرش: 17 فروردین 1401

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