ارتباط سطح سرمی منیزیم و وقوع فیبریلاسیون دهلیزی بعد از جراحی بای‌پس عروق کرونر

نوع مقاله : مقاله های پژوهشی

نویسندگان

1 استادیار، بخش جراحی قلب، مرکز توسعه‌ی تحقیقات بالینی، مرکز آموزشی درمانی بوعلی سینا، دانشگاه علوم پزشکی قزوین، قزوین، ایران

2 پزشک عمومی، مرکز توسعه‌ی تحقیقات بالینی، مرکز آموزشی درمانی بوعلی سینا، دانشگاه علوم پزشکی قزوین، قزوین، ایران

3 استاد، گروه سم‌شناسی بالینی، دانشکده‌ی پزشکی، دانشگاه علوم پزشکی قزوین، قزوین، ایران

4 دکتری تخصصی، بخش انگل‌شناسی و قارچ‌شناسی، مرکز تحقیقات رشد کودکان، پژوهشکده‌ی پیش‌گیری از بیماری‌های غیر واگیر، دانشگاه علوم پزشکی قزوین، قزوین، ایران

چکیده

مقدمه: فیبریلاسیون دهلیزی، آریتمی فوق بطنی و یکی از رایج‌ترین عوارض بعد از عمل جراحی بای‌پس عروق کرونر است. مطالعه‌ی حاضر با هدف تعیین ارتباط سطح سرمی منیزیم و وقوع فیبریلاسیون دهلیزی پس از عمل جراحی بای‌پس عروق کرونر در بیماران مراجعه کننده به بیمارستان بوعلی سینای قزوین انجام گردید.روش‌ها: طی این مطالعه‌ی مشاهده‌ای، 137 بیمار کاندیدای جراحی بای‌پس عروق کرونر وارد مطالعه شدند. اطلاعات دموگرافیک و سوابق بیماری برای بیماران ثبت گردید. بیماران به مدت سه روز تحت نظر بودند و روزانه سطح سرمی منیزیم آن‌ها ارزیابی شد. بیماران بر اساس وقوع یا عدم وقوع هایپومنیزیمی در روز عمل و روزهای اول تا سوم پس از عمل جراحی به دو گروه هیپومنیزیمی و نورمومنیزیمی تقسیم شدند. بیماران از نظر بروز آریتمی‌های قلبی پایش و در صورت نیاز، سولفات منیزیم تزریق و دز آن ثبت شد. در نهایت، داده‌های حاصل از مطالعه با استفاده از نرم‌افزار SPSS واکاوی شد.یافته‌ها: اختلاف سطح سرمی منیزیم در روزهای قبل و روز جراحی و اول تا سوم پس از جراحی در تمامی فواصل مطالعه از نظر آماری میان دو گروه معنی‌دار بود. تفاوت میان دو گروه از نظر بروز فیبریلاسیون دهلیزی از لحاظ آماری معنی‌دار نبود (797/0 = P)؛ اما تفاوت آماری معنی‌داری میان دو گروه از نظر زمان بروز فیبریلاسیون دهلیزی دیده شد (014/0 = P).نتیجه‌گیری: همچنان، نقش منیزیم در بروز فیبریلاسیون دهلیزی پس از جراحی بای‌پس عروق کرونر به طور دقیق مشخص نیست و در این زمینه، نیاز به مطالعات بیشتر می‌باشد.

کلیدواژه‌ها

عنوان مقاله [English]

The Relationship between Serum Magnesium Level and Atrial Fibrillation Following Coronary Artery Bypass Grafting

نویسندگان [English]

  • Seyed Saeed Farzam 1
  • Sarvin Rajabi 2
  • Amir Mohammad Kazemifar 3
  • Samira Dodangeh 4
1 Assistant Professor, Department of Cardiovascular Surgery, Clinical Research Development Unit, Buali Hospital, Qazvin University of Medical Sciences, Qazvin, Iran
2 General Practitioner, Clinical Research Development Unit, Buali Hospital, Qazvin University of Medical Sciences, Qazvin, Iran
3 Professor, Department of Clinical Toxicology, School of Medicine, Qazvin University of Medical Sciences, Qazvin, Iran
4 PhD, Department of Medical Parasitology and Mycology, Children Growth Research Center, Research Institute for Prevention of Non-Communicable Diseases, Qazvin University of Medical Sciences, Qazvin, Iran
چکیده [English]

Background: Atrial fibrillation is a supraventricular arrhythmia, and is one of the most common complication after coronary artery bypass graft surgery (CABG). The aim of this study was to determine the relationship between serum magnesium level and the occurrence of atrial fibrillation after CABG in patients referred to Bu-Ali Sina hospital in Qazvin, Iran.Methods: 137 patients who were candidates for CABG surgery were included in this observational study. Demographic information and medical records were recorded for patients. Patients were monitored for three days, and their serum magnesium levels were assessed daily. Patients were divided into hypomagnesium and normomagnesium groups based on the presence or absence of hypomagnesemia in the surgery day and the first to third day after surgery. Patients were monitored for cardiac arrhythmias, and if necessary, magnesium sulfate injection and its dose were recorded. Finally, the data obtained from the study were analyzed using SPSS software.Findings: Serum magnesium level was significantly different between the two groups before and on the day of surgery, and one to three days after surgery at all study intervals. The difference between the two groups in terms of atrial fibrillation incidence was not statistically significant (P = 0.797); but there was a statistically significant difference between the two groups in terms of atrial fibrillation incidence time (P = 0.014).Discussion: The role of magnesium in incidence of atrial fibrillation after CABG surgery is still unclear, and further studies are needed.

کلیدواژه‌ها [English]

  • Coronary Artery Bypass
  • Magnesium
  • Arrhythmia

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سابقه مقاله

  • تاریخ دریافت: 15 بهمن 1399
  • تاریخ بازنگری: 11 آبان 1403
  • تاریخ پذیرش: 17 فروردین 1401

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