The Effect of Adjustment of Positive End-Expiratory Pressure (PEEP) and Fraction of Inspired Oxygen (FiO2) Based on Arterial Blood Oxygen Pressure on the Care and Treatment Outcomes of Patients in Intensive Care Unit (ICU)

Document Type : Original Article (s)

Authors

1 MSc Student, Department Nursing, School of Nursing and Midwifery AND Nursing Care Research Center in Chronic Diseases, Jundishapur University of Medical Sciences, Ahvaz, Iran

2 Assistant Professor, Department of Anesthesiology, Intensive Care Unit, Imam Khomeini Hospital, School of Medicine, Jundishapur University of Medical Sciences, Ahvaz, Iran

3 Associate Professor, Department Nursing, School of Nursing and Midwifery AND Nursing Care Research Center in Chronic Diseases, Jundishapur University of Medical Sciences, Ahvaz, Iran

4 Instructor, Department Nursing, School of Nursing and Midwifery AND Nursing Care Research Center in Chronic Diseases, Jundishapur University of Medical Sciences, Ahvaz, Iran

5 Assistant Professor Department of Biostatistics and Epidemiology, School of Health, Jundishapur University of Medical Sciences, Ahvaz, Iran

Abstract

Background: One of the problems of the treatment system is the high mortality and length stay of patients in the intensive care unit (ICU), which has high costs. The aim of this study was to determine the effect of adjustment of positive end-expiratory pressure (PEEP) and fraction of inspired oxygen (FiO2) based on PaO2 on the care and treatment outcomes of ICU patients.Method: This was a randomized clinical trial study in which the statistical population consisted of all patients admitted to the ICU of Imam Khomeini hospital in Ahvaz, Iran, in the second half of 2020. 40 samples were selected based on available sampling method, and randomly divided into two groups of intervention and control. To collect the data, a demographic information questionnaire as well as Sequential Organ Failure Assessment (SOFA) scoring system were used. In the intervention group, adjustment of PEEP and FiO2 was performed based on PaO2 of patients in 7 days.Findings: There was no difference between the two groups in terms of demographic variables. The mean scores of disease severity before intervention in the two groups were not statistically different; but after the intervention, disease severity score, duration of ventilator connection, and length of ICU stay were significantly lower in the intervention group.Conclusion: The adjustment of PEEP and FiO2 based on PaO2 is effective in reducing the disease severity score, duration of ventilator connection, and ICU stay. It should be used as a nursing intervention in coordination with treatment team to reduce the consequences of hospitalization in ICU.

Keywords

References

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Journal of Isfahan Medical School
Volume 39, Issue 651 - Serial Number 651
November and December 2022
Pages 894-900

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History

  • Receive Date: 14 July 2021
  • Revise Date: 01 November 2024
  • Accept Date: 06 April 2022

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