The Prevalence and Antibiotic Susceptibility Pattern of Isolated Microorganisms from Hospitalized Patients with Heart Diseases

Document Type : مقاله کوتاه

Authors

1 Department of Medical Laboratory Sciences, Student Research Center, Paramedical School, Tabriz University of Medical Sciences, Tabriz, Iran

2 Associate Professor, Infectious Diseases and Tropical Medicine Research Center, Tabriz University of Medical Science, Tabriz, Iran

3 Assistant Professor, Department of Clinical Epidemiology, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran

4 Student of Medicine, Student Research Committee, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

5 Associate Professor, Department of Medical Laboratory Sciences, School of Paramedicine, Tabriz University of Medical Sciences, Tabriz, Iran

Abstract

Background: Urinary tract infections (UTI) are the most common infections in community and hospitalized patients. Irrational consumption of antibiotics and creation of drug resistance make the treatment of these infections more difficult. Hence, determination of antibiotic resistance pattern is necessary to manage the treatment correctly; this was the main purpose of the present survey.Methods: This was a retrospective and cross-sectional study with targeted community of 2566 hospitalized patients with heart diseases in Tabriz Shahid Madani Cardiovascular Hospital, Iran, during 2009-2010. Urine cultures were studied for type of microorganisms and their antibiotic susceptibility patterns. The gathered data were analyzed.Findings: Out of 2566 urine cultures, 479 cases (18.7%) were positive for pathogenic microorganisms (bacteria and yeasts). Three hundred and forty eight (72.3%) patients were women and 131 (27.7%) were men. Mean age was 61.0 ± 18.6 years. Enteric gram-negative rods were the most frequent agents of UTI in different units of the hospital. Among isolated microorganisms, the highest susceptibility [306 cases (64%)] was reported for amikacin. Three hundred and twenty four cases among of all bacterial UTI (79%) were community-acquired infections. In addition, the laboratory had not followed reference guideline in reporting antibiotic susceptibility test results and performing antibiogram test for Staphylococcus aureus.Conclusion: We suggest amikacin for treatment of UTI in this hospital. Also, disobeying laboratory guidelines may impact treatment outcome and prevalence of antibiotic resistance in this medical center.

Keywords

References

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Journal of Isfahan Medical School
Volume 31, Issue 260 - Serial Number 260
September and October 2014
Pages 1848-1854

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History

  • Receive Date: 06 June 2013
  • Revise Date: 01 November 2024
  • Accept Date: 06 April 2022

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