Effect of Concentrated Pomegranate Juice on Cardiovascular Factors in Patients with Type 2 Diabetes

Document Type : مقاله کوتاه

Authors

1 Assistant Professor, Department of Nutrition, Nutrition and Metabolic Diseases Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran

2 Associate Professor, Department of Nutrition, Hyperlipidemia Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran

3 Assistant Professor, Department of Endocrinology and Metabolism, Health Research Institute, Diabetes Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran

4 Assistant Professor, Department of Biostatistics and Epidemiology, School of Public Health, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran

5 PhD Student, Department of Nutrition, Student Research Committee, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran

6 Associate Professor, Department of Food Hygiene, School of Veterinary Medicine, Shahid Chamran University, Ahvaz, Iran

7 Department of Nutrition, School of Paramedical Sciences, Arvand International Branch, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran

Abstract

Background: Although current information shows that pomegranate in patients with type 2 diabetes mellitus can improve control of blood sugar and lipids profile, there are controversial results about these findings. This survey investigated the influence of concentrated pomegranate juice (CPJ) on fasting blood sugar, lipid profile, total antioxidant capacity (TAC) and blood pressure (BP) in patients with type 2 diabetes mellitus.Methods: This quasi-clinical trial study was conducted on 40 patients with type 2 diabetes mellitus in Golestan hospital of Ahvaz, Iran, in 2013. Fasting blood samples were taken at baseline and after 4 weeks of intervention to measure the fasting blood sugar, lipid profile, and total antioxidant capacity.Findings: While high-density lipoprotein cholesterol (HDL-C) significantly increased after the intervention, total antioxidant capacity significantly increased (P < 0.001). No changes were made in levels of fasting blood sugar, triglyceride (TG), low-density lipoprotein cholesterol (LDL-c), and blood pressure after the intervention.Conclusion: It is concluded that concentrated pomegranate juice have significant positive effects on HDL and total antioxidant capacity in patients with type 2 diabetes which may be attributed to its polyphenolic content. Further investigations are needed with stronger design and larger sample size.

Keywords

References

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Journal of Isfahan Medical School
Volume 32, Issue 309 - Serial Number 309
September and October 2015
Pages 1944-1953

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History

  • Receive Date: 12 August 2014
  • Revise Date: 01 November 2024
  • Accept Date: 06 April 2022

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