Ginger and Diabetic Nephropathy: A Letter to the Editor

Document Type : Letter to Editor

Authors

1 Professor, Medical Plants Research Center, Shahrekord University of Medical Sciences, Shahrekord, Iran

2 General Practitioner, Medical Plants Research Center, Shahrekord University of Medical Sciences, Shahrekord, Iran

3 Professor, Department of Nephrology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

Abstract

Dear Editor-in-Chief,Recently, much attention had been directed toward protective efficacy of Ginger in diabetic nephropathy. Recent studies have shown the combination of metformin and ginger extract may be more effective for the control of diabetes and may have additive protective efficacy on diabetic nephropathy. In this regard, to understand the kidney protective properties of Ginger better, especially in combination with metformin, more experimental rat models or clinical studies are suggested.

Keywords


  1. Tzeng TF, Liou SS, Chang CJ, Liu IM. The ethanol extract of zingiber zerumbet attenuates streptozotocin-induced diabetic nephropathy in rats. Evid Based Complement Alternat Med 2013; 2013: 340645.
  2. Tolouian R, Hernandez T. Prediction of diabetic nephropathy: The need for a sweet biomarker. J Nephropathol 2013; 2(1): 4-5.
  3. Vafa M, Mohammadi F, Shidfar F, Sormaghi MS, Heidari I, Golestan B, et al. Effects of cinnamon consumption on glycemic status, lipid profile and body composition in type 2 diabetic patients. Int J Prev Med 2012; 3(8): 531-6.
  4. Hajivandi A, Amiri M. World kidney day 2014: Kidney disease and elderly. J Parathyr Dis 2014; 2(1): 3-4.
  5. Nasri H, Shirzad H. Toxicity and safety of medicinal plants. J Herb Med Plarmacol 2013; 2(2): 21-2.
  6. Nasri H: Acute kidney injury and beyond. J Ren Inj Prev 2012, 1(1): 1–2.
  7. Rafieian-Kopaie M, Nasri H. Silymarin and kidney. J Ren Inj Prev 2012; 1(1): 3-6.
  8. Rouhi H, Ganji F. Effects of N-acetyl cysteine on serum lipoprotein (a) and proteinuria in type 2 diabetic patients. J Nephropathol 2013; 2(1): 61-6.
  9. Nasri H. Impact of diabetes mellitus on parathyroid hormone in hemodialysis patients. J Parathyr Dis 2013; 1(1): 9-11.
  10. Nasri H. Comment on: serum cholesterol and LDL-C in association with level of diastolic blood pressure in type 2 diabetic patients. J Ren Inj Prev 2012; 1(1): 13-4.
  11. Nasri H, Nematbakhsh M, Ghobadi S, Ansari R, Shahinfard N, Rafieian-Kopaei M. Preventive and curative effects of ginger extract against histopathologic changes of gentamicin-induced tubular toxicity in rats. Int J Prev Med 2013; 4(3): 316-21.
  12. Gheshlaghi F. Toxic renal injury at a glance. J Ren Inj Prev 2012; 1(1): 15–6.
  13. Tavafi M. Diabetic nephropathy and antioxidants. J Nephropathol 2013; 2(1): 20-7.
  14. Nasri H, Rafieian-Kopaei M. Metformin improves diabetic kidney disease. J Nephropharmacol 2012; 1(1): 1–2.
  15. Nasri H, Rafieian-Kopaei M. Herbal medicine and diabetic kidney disease. J Nephropharmacol 2013; 2(1): 1-2.
  16. Nasri H. Elevated serum parathyroid hormone is a heart risk factor in hemodialysis patients. J Parathy Dis 2013; 1(1): 13-4.
  17. Behradmanesh S, Nasri P. Serum cholesterol and LDL-C in association with level of diastolic blood pressure in type 2 diabetic patients. J Ren Inj Prev 2012; 1(1): 23-6.
  18. Baradaran A. Beyond mineral metabolism, the bright immunomodulatory effect of vitamin D in renal disease. J Nephropharmacol 2012; 1(2): 17-8.
  19. Amini FG, Rafieian-Kopaei M, Nematbakhsh M, Baradaran A, Nasri H. Ameliorative effects of metformin on renal histologic and biochemical alterations of gentamicin-induced renal toxicity in Wistar rats. J Res Med Sci 2012; 17(7): 621-5.
  20. Rafieian-Kopaei M, Baradaran A, Merrikhi A, Nematbakhsh M, Madihi Y, Nasri H. Efficacy of co-administration of garlic extract and metformin for prevention of gentamicin-renal toxicity in wistar rats: a biochemical study. Int J Prev Med 2013; 4(3): 258-64.
  21. Amiri M, Nasri H. Secondary hyperparathyroidism in chronic kidney disease patients; current knowledge. J Parathyr Dis 2014; 2(1): 1-2.
  22. Kim J, Shon E, Kim CS, Kim JS. Renal podocyte injury in a rat model of type 2 diabetes is prevented by metformin. Exp Diabetes Res 2012; 2012: 210821.
  23. Baradaran A. Primary hyperparathyroidism and kidney; recent findings. J Parathyr Dis 2014; 2(1): 5-6.
  24. Khajehdehi P. Turmeric: reemerging of a neglected Asian traditional remedy. J Nephropathol 2012; 1(1): 17-22.
  25. Nasri H, Rafieian-Kopaei M. Preventive role of erythropoietin against aminoglycoside renal toxicity induced nephropathy; current knowledge and new concepts. J Ren Inj Prev 2013; 2(1): 29-30.
  26. Kadkhodaee M. Erythropoietin; bright future and new hopes for an old drug. J Nephropathol 2012; 1(2): 81-2.
  27. Nasri H. Renoprotective effects of garlic. J Ren Inj Prev 2012; 2(1): 27-8.
  28. Rafieian-Kopaei M, Nasri H. Vitamin D therapy in diabetic kidney disease. J Nephropharmacol 2014; 3(1): 3-4.
  29. Rafieian-Kopaei M, Baradaran A. Teucrium polium and kidney. J Ren Inj Prev 2013; 2(1): 3-4.
  30. Tavafi M. Protection of renal tubules against gentamicin induced nephrotoxicity. J Ren Inj Prev 2012; 2(1): 5-6.