Demographic, Clinical, and Para clinical Features in Patients with COVID-19 and ST-Elevation Myocardial Infarction

Document Type : Original Article(s)

Authors

1 Associate Professor of Cardiology, Department of Cardiology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

2 Resident of Internal Medicine, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

3 Assistant Professor, Department of Internal Medicine, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

4 Assistant Professor, Department of Community of Medicine. Isfahan University of Medical Sciences, Isfahan, Iran

Abstract

Background: The aims of this study were to determine the prognosis of patients with heart infarction who were also diagnosed with COVID-19 disease and investigate its relationship with underlying diseases and blood factors and the severity of pulmonary involvement.
Methods: This cross-sectional descriptive study gathered data from medical records of patients hospitalized in Alzahra, Chamran, and Khorsheed hospitals in Isfahan city betveen 2020 and 2021. The study included Individuals over 18 years old who were diagnosed with myocardial infarction and positive polymerase chain reaction (PCR) test placed under angiography.The variables examined included age, gender, comorbidities, medications, smoking history, vaccination status, laboratory findings, echocardiography, angiography, and mortality. The data were analyzed using logistic regression.
 Findings: A total of 65 patients were examined. The most common comorbidity was hypertension (55.4%) and the most prevalent symptom was chest pain (84.6%). There was a decreased in Left ventricular ejection fraction (38.2%), which was significant in patients with ST-elevation myocardial infarction (33.5% vs. 43.7%, P = 0.0009). Thrombosis was observed in 14 patients, which was more common in the ST-elevation myocardial infarction (STEMI) group compared to the non-ST-elevation myocardial infarction (NSTEMI) group (30.8% vs. 7.7%,
P = 0.03). The most involved artery was LAD (60%). There was no significant association between the severity of COVID-19 and myocardial infarction subtypes. Moreover, these subgroups did not exhibit a significant association with mortality rates.
Conclusion: Our study did not find a significant association between the severity of COVID-19 and myocardial infarction subtypes.

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Main Subjects

References

  1. Wu Z, McGoogan JM. Characteristics of and important lessons from the coronavirus disease 2019 (COVID-19) outbreak in China: summary of a report of 72 314 cases from the Chinese Center for Disease Control and Prevention. JAMA 2020; 323(13): 1239-42.
  2. Shi S, Qin M, Shen B, Cai Y, Liu T, Yang F, et al. Association of cardiac injury with mortality in hospitalized patients with COVID-19 in Wuhan, China. JAMA Cardiol 2020; 5(7): 802-10.
  3. Zitelny E, Newman N, Zhao D. STEMI during the COVID-19 pandemic-an evaluation of incidence. Cardiovasc Pathol 2020; 107232.
  4. Xiang D, Xiang X, Zhang W, Yi S, Zhang J, Gu X, et al. Management and outcomes of patients with STEMI during the COVID-19 pandemic in China. J Am Coll Cardiol 2020; 76(11): 1318-24.
  5. Bangalore S, Sharma A, Slotwiner A, Yatskar L, Harari R, Shah B, et al. ST-segment elevation in patients with Covid-19—a case series. N Engl J Med 2020; 382(25): 2478-80.
  6. Huang C, Wang Y, Li X, Ren L, Zhao J, Hu Y, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet 2020; 395(10223): 497-506.
  7. Popovic B, Varlot J, Metzdorf PA, Jeulin H, Goehringer F, Camenzind E. Changes in characteristics and management among patients with ST‐elevation myocardial infarction due to COVID‐19 infection. Catheter Cardiovasc Interv 2021; 97(3): E319-E26.
  8. Hamadeh A, Aldujeli A, Briedis K, Tecson KM, Sanz-Sánchez J, Al-Obeidi A, et al. Characteristics and outcomes in patients presenting with COVID-19 and ST-segment elevation myocardial infarction. The Am J Cardiol 2020; 131: 1-6.
  9. Choi S, Jang WJ, Song YB, Lima JA, Guallar E, Choe YH, et al. D-dimer levels predict myocardial injury in ST-segment elevation myocardial infarction: a cardiac magnetic resonance imaging study. PLoS One 2016; 11(8): e016095.
  10. Gensini GG. A more meaningful scoring system for determining the severity of coronary heart disease. Am J Cardiol 1983; 51(3): 606.
  11. Gong P, Luo SH, Li XL, Guo YL, Zhu CG, Xu RX, et al. Relation of ABO blood groups to the severity of coronary atherosclerosis: an Gensini score assessment. Atherosclerosis 2014; 237(2): 748-53.
  12. Askarian M, Fu L, Taghrir MH, Borazjani R, Shayan Z, Taherifard E, et al. Factors affecting COVID-19 vaccination intent among Iranians: COVID-19 vaccination acceptance. [Online]. [cited Dec 03 2020]; Avilable from: URL:

https://ssrn.com/abstract=3741968

  1. Alaarag A, Hassan T, Samir S, Naseem M. Clinical and angiographic characteristics of patients with STEMI and confirmed diagnosis of COVID-19: an experience of Tanta University Hospital. Egypt Heart J 2020; 72: 68.
  2. Kite TA, Ludman PF, Gale CP, Wu J, Caixeta A, Mansourati J, et al. International prospective registry of acute coronary syndromes in patients with COVID-19.
    J Am Coll Cardiol 2021; 77(20): 2466-76.
  3. Guo T, Fan Y, Chen M, Wu X, Zhang L, He T, et al. Cardiovascular implications of fatal outcomes of patients with coronavirus disease 2019 (COVID-19). JAMA Cardiol 2020; 5(7): 811-8.

 

Journal of Isfahan Medical School
Volume 41, Issue 719
3rd Week, July
July and August 2023
Pages 338-345

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History

  • Receive Date: 17 December 2022
  • Revise Date: 28 May 2023
  • Accept Date: 31 May 2023

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