The relationship of Maternal Serum Magnesium Levels and the Incidence of Low-Birth-Weight Infants: A Case-Control Study

Document Type : Original Article (s)

Authors

1 PhD Student, Department of Epidemiology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran

2 Lecturer, Department of Midwifery, School of Nursing and Midwifery, Islamic Azad University, Karaj Branch, Karaj, Iran

3 Lecturer, Department of Midwifery, School of Nursing and Midwifery, Islamic Azad University, Birjand Branch, Birjand, Iran

Abstract

Background: Low birth weight is the most important public health problem, especially in the developing countries, associated with many complications. Magnesium, an essential element for many enzymes, have been studied in recent decades and can reduce preterm labor and low birth weight. Hence, this study aimed to investigate the relationship of maternal serum magnesium levels and the incidence of low-birth-weight infants.Methods: In this case-control study, 21 low- (cases) and 39 normal-birth-weight (control group) infants were studied. Information was collected by infant physical examination, interview with the mother and maternal blood laboratory tests. For the measurement of maternal serum magnesium level, atomic absorption spectrometry method was used. The collected data were analyzed using independent t and chi-square tests.Findings: The mean maternal serum magnesium level was significantly (P = 0.001) lower in the case group (2.24 ± 0.07 mg) compared with the control group (2.61 ± 0.09 mg). Low maternal serum magnesium level is a risk factor for incidence of low birth weight .Conclusion: Maternal serum magnesium level is a predictive risk factor for low birth weight. Therefore, to reduce the incidence of low birth weight, as one of the most important causes of infant mortality, oral administration of magnesium and dietary advices can be taken.

Keywords

References

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Journal of Isfahan Medical School
Volume 32, Issue 282 - Serial Number 282
March and April 2014
Pages 507-513

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History

  • Receive Date: 20 November 2013
  • Revise Date: 01 November 2024
  • Accept Date: 06 April 2022

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