The Association between Serum Lactate Level and Post CABG Complications in Cardiac Patients

Document Type : Original Article(s)

Authors

1 Assistant Professor, Department of Cardiosurgery, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.

2 Cardiologist, Delasa Research Center, Isfahan, Iran.

3 Researcher, Isfahan Cardiovascular Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran.

4 Medical Student, Student Research Committee, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.

5 Anesthesiologist, Isfahan University of Medical Sciences, Isfahan, Iran.

6 Nurse, Delasa Research Center, Isfahan, Iran.

7 General Practitioner, Isfahan Cardiovascular Research Center, Isfahan cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran.

Abstract

Background: The aim of this study was to evaluate the relationship between postoperative serum lactate levels and outcome in patients undergoing coronary artery bypass graft surgery (CABG) and verify the clinical impact of hyperlactatemia (HL) during CABG in terms of postoperative morbidity and mortality rate.Methods: In this prospective study, 92 patients underwent open heart surgery. Demographic data, lactate levels, PH, 48 hours serum creatinin after surgery (mg per cent), left ventricular ejection fraction, Inotropic Drugs and the duration of  use and the duration of  intensive care unit (ICU) admission t and deaths were collected.Finding: Mortality rate was 3.3 percent, the average duration of hospitalization was 8.8 days and the duration of ICU admission was 47.27 hours. In 82.6% of the patients increased lactic acid was observed; while 17.4% of patients had a low lactate serum concentration during ICU admission.Conclusion: The findings of this study showed an association between lactate serum levels and the duration  of  ICU admission and duration of hospitalization, so hyperlactatemia could be a prognostic factor and could predict the mortality and the severity of complications in the patients undergone CABG.      

Keywords

References

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Journal of Isfahan Medical School
Volume 29, Issue 128 - Serial Number 128
January and February 2011
Pages 147-154

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History

  • Receive Date: 10 March 2011
  • Revise Date: 23 May 2024
  • Accept Date: 06 April 2022

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