Fractional CO2 Laser as an Effective Modality in Treatment of Striae Alba in Skin Types III and IV

Document Type : Original Article (s)

Authors

1 Associate Professor, Skin Disease and Leishmaniasis Research Center AND Department of Dermatology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

2 Skin Diseases and Leishmaniasis Research Center, Isfahan University of Medical Sciences, Isfahan, Iran

3 Associate Professor, Skin and Stem Cell Research Center, Tehran University of Medical Sciences, Tehran, Iran

Abstract

Background: Rapid stretching of the skin over the weak connective tissue leads to development of striae distensae. Recently, researchers have shown special interest towards use of fractional photothermolysis in treatment of striae and several studies have shown its usefulness. We aimed to assess the efficacy of Fractional CO2 laser in treatment of striae alba.Methods: A randomized clinical trial was carried out in 6 women with striae alba. Ninety two striae were randomly divided into two groups. Five sessions of laser resurfacing were performed in group 1, every 2-4 weeks. Group 2 was treated with 10% glycolic acid and 0.05% tretinoin cream nightly. Photographs were taken from the striae before and two weeks after the end of the treatment. Mean surface area of striae compared between two groups. Patients’ views regarding the degree of improvement were assessed via visual analogue scale (VAS).Findings: Mean difference of striae surface area was significantly more after treatment in group 1 (-37.1 ± 15.6 cm2) in comparison with group 2 (-7.9 ± 9.0 cm2) (P < 0.001). Mean VAS was significantly higher in group 1 (3.05 ± 0.74) compared to group 2 (0.63 ± 0.66) (P < 0.001).Conclusion: Fractional photothermolysis via Fractional CO2 laser seems to be an effective method for treatment of striae alba.

Keywords

References

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Journal of Isfahan Medical School
Volume 31, Issue 269 - Serial Number 269
November and December 2014
Pages 2285-2294

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History

  • Receive Date: 21 January 2014
  • Revise Date: 26 May 2024
  • Accept Date: 06 April 2022

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