The Effect of Infectious Disease Specialists Deployment Plan on Using Antibiotics in Alzahra Hospital, Isfahan, Iran

Document Type : مقاله کوتاه

Authors

1 Associate Professor, Department of Infectious Diseases, School of Medicine AND Nosocomial Infection Research Center, Isfahan University of Medical Sciences, Isfahan, Iran

2 Associate Professor, Department of Infectious Diseases, School of Medicine AND Infectious Diseases and Tropical Medicine Research Center, Isfahan University of Medical Sciences, Isfahan, Iran

3 Student of Medicine, School of Medicine AND Student Research Committee, Isfahan University of Medical Science, Isfahan, Iran

4 Epidemiologist, School of Medicine, Isfahan University of Medical Science, Isfahan, Iran

Abstract

Background: One of the most prevalent problems among hospitalized patients in intensive care units (ICUs) is infectious diseases that lead to high usage of antibiotics. This study was designed to evaluate the antibiotic usage in intensive care units of Alzahra Hospital, Isfahan, Iran, before (in 2010) and after (in 2014) the presence of infectious disease specialists.Methods: In a cross-sectional study, we measured the total rate of antibiotics usage in intensive care units of Alzahra Hospital in 2010 and 2014. SPSS22 software was used for the statistical analysis.Findings: Of the 39 evaluated antibiotics, use of 23 antibiotics (53.8%) were increased and of 16 (46.2%) were decreased after infectious disease specialists arrival. There was not a significant statistical difference between the mean of antibiotics consumption in 2010 and 2014 (P = 0.29).Conclusion: We suggest that additional studies should be performed to evaluate the causes of increasing usage of some antibiotics consumption and decreasing of others such as price, indication and contraindications, and access of antibiotics.

Keywords

References

  1. Malacarne P, Rossi C, Bertolini G. Antibiotic usage in intensive care units: a pharmaco-epidemiological multicentre study. J Antimicrob Chemother 2004; 54(1): 221-4.
  2. Bergmans DC, Bonten MJ, Gaillard CA, van Tiel FH, van der Geest S, de Leeuw PW, et al. Indications for antibiotic use in ICU patients: a one-year prospective surveillance. J Antimicrob Chemother 1997; 39(4): 527-35.
  3. Lee KR, Leggiadro RJ, Burch KJ. Drug use evaluation of antibiotics in a pediatric teaching hospital. Infect Control Hosp Epidemiol 1994; 15(11): 710-2.
  4. De AG, Restuccia G, Cauda R, Tacconelli E. How could we reduce antibiotic use in critically ill patients? Infect Disord Drug Targets 2011; 11(4): 376-83.
  5. Gruson D, Hilbert G, Vargas F, Valentino R, Bebear C, Allery A, et al. Rotation and restricted use of antibiotics in a medical intensive care unit. Impact on the incidence of ventilator-associated pneumonia caused by antibiotic-resistant gram-negative bacteria. Am J Respir Crit Care Med 2000; 162(3 Pt 1): 837-43.
  6. McGowan JE, Jr. Do intensive hospital antibiotic control programs prevent the spread of antibiotic resistance? Infect Control Hosp Epidemiol 1994; 15(7): 478-83.
  7. Murray BE. Can antibiotic resistance be controlled? N Engl J Med 1994; 330(17): 1229-30.
  8. Arnold HM, Micek ST, Skrupky LP, Kollef MH. Antibiotic stewardship in the intensive care unit. Semin Respir Crit Care Med 2011; 32(2): 215-27.
  9. Isturiz RE, Carbon C. Antibiotic use in developing countries. Infect Control Hosp Epidemiol 2000; 21(6): 394-7.
  10. Ziment I. Complications of antibiotic therapy. Calif Med 1972; 117(5): 24-48.
  11. Carey B, Cryan B. Antibiotic misuse in the community--a contributor to resistance? Ir Med J 2003; 96(2): 43-4, 46.
  12. WHO reports. Available from: URL:http://www.euro.who.int/en/what-we-do/health-topics/disease-prevention/antimicrobial-resistance/antibiotic-resistance.
  13. World Health organization. The top 10 causes of death.The 10 leading causes of death by broad income group [Online]. [cited 2008]; Available from:URL:http://www.who.int/mediacentre/factsheets/fs310/en
  14. Conly J. Antimicrobial resistance in Canada. CMAJ 2002; 167(8): 885-91.
Journal of Isfahan Medical School
Volume 32, Issue 306 - Serial Number 306
September and October 2014
Pages 1797-1804

Files

History

  • Receive Date: 21 August 2014
  • Revise Date: 23 May 2024
  • Accept Date: 06 April 2022

Share

How to cite

Statistics