Association of Dairy Consumption and Irritable Bowel Syndrome in Iranian Adults

Document Type : Original Article (s)

Authors

1 Student of Medicine, Student Research Committee, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

2 General Practitioner, Student Research Committee, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

3 Food Security Research Center AND Student Research Committee, School of Nutrition and Food Science, Isfahan University of Medical Sciences, Isfahan, Iran

4 General Practitioner, Integrative Functional Gastroenterology Research Center, Isfahan University of Medical Sciences, Isfahan, Iran

5 Professor, Obesity and Eating Habits Research Center AND Department of Community Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran

6 Associate Professor, Endocrine and Metabolism Research Center AND Integrative Functional Gastroenterology Research Center AND Department of Biostatistics and Epidemiology, School of Health, Isfahan University of Medical Sciences, Isfahan, Iran

7 Professor, Integrative Functional Gastroenterology Research Center, Isfahan University of Medical Sciences, Isfahan, Iran

Abstract

Background: Dietary intakes, especially dairy products, can be the cause of change or onset of the symptoms in functional gastrointestinal disorders (FGIDs) like irritable bowel syndrome (IBS). This study aimed to investigate the relationship between dairy consumption and prevalence of IBS in Iranian adults.Methods: This cross-sectional study was based on SEPAHAN project that was done among 4763 of staffs of Isfahan University of Medical Sciences, Iran, during 2 phases. IBS and nutrient intake were assessed using ROME III criteria and validated food frequency questionnaire (FFQ), respectively. Completed questionnaires of the 2 phases which were of the subjects with lactose intolerance were excluded which resulted in 2849 questionnaires. Cases were devided to 3 consecutive groups of dairy consumption named dairy intake tertiles. The odds ratios (OR) were evaluated for IBS in dairy intake tertiles.Findings: Prevalence of IBS was estimated 20.7%. There was no significant difference between odds ratio of IBS in crude models of low- and high-fat dairy consumption. Controlling for potential confounders did not change the results. However, there was a positive and negative association between consumption of average amount of high fat (OR: 1.11, Confidence interval of 95%: 0.87-1.41) and higher intake of low-fat dairy products (OR: 0.87, Confidence interval of 95%: 0.69-1.10) with higher prevalence of IBS. In addition, abdominal pain was related adversely to average amount of dairy consumption (OR: 0.79, Confidence interval of 95%: 0.64-0.98).Conclusion: There was no significant association between IBS prevalence and dairy consumption; although, average intake of dairy products can be protective against abdominal pain.

Keywords

References

  1. Longstreth GF, Thompson WG, Chey WD, Houghton LA, Mearin F, Spiller RC. Functional bowel disorders. Gastroenterology 2006; 130(5): 1480-91.
  2. Lovell RM, Ford AC. Global prevalence of and risk factors for irritable bowel syndrome: a meta-analysis. Clin Gastroenterol Hepatol 2012; 10(7): 712-21.
  3. Jahangiri P, Jazi MS, Keshteli AH, Sadeghpour S, Amini E, Adibi P. Irritable bowel syndrome in Iran: SEPAHAN systematic review no. 1. Int J Prev Med 2012; 3(Suppl 1): S1-S9.
  4. Drossman DA, Camilleri M, Mayer EA, Whitehead WE. AGA technical review on irritable bowel syndrome. Gastroenterology 2002; 123(6): 2108-31.
  5. Drossman DA. The functional gastrointestinal disorders and the Rome III process. Gastroenterology 2006; 130(5): 1377-90.
  6. Faresjo A, Johansson S, Faresjo T, Roos S, Hallert C. Sex differences in dietary coping with gastrointestinal symptoms. Eur J Gastroenterol Hepatol 2010; 22(3): 327-33.
  7. Spiller RC. Potential future therapies for irritable bowel syndrome: will disease modifying therapy as opposed to symptomatic control become a reality? Gastroenterol Clin North Am 2005; 34(2): 337-54.
  8. Farup PG, Monsbakken KW, Vandvik PO. Lactose malabsorption in a population with irritable bowel syndrome: prevalence and symptoms. A case-control study. Scand J Gastroenterol 2004; 39(7): 645-9.
  9. Gudmand-Hoyer E. The clinical significance of disaccharide maldigestion. Am J Clin Nutr 1994; 59(3 Suppl): 735S-41S.
  10. Vesa TH, Seppo LM, Marteau PR, Sahi T, Korpela R. Role of irritable bowel syndrome in subjective lactose intolerance. Am J Clin Nutr 1998; 67(4): 710-5.
  11. Adibi P, Keshteli AH, Esmaillzadeh A, Afshar H, Roohafza H, Bagherian-Sararoudi R, et al. The study on the epidemiology of psychological, alimentary health and nutrition (SEPAHAN): Overview of methodology. J Res Med Sci 2012; 17(Spec 2): S291-S297.
  12. Keshteli A, Esmaillzadeh A, Rajaie S, Askari G, Feinle-Bisset C, Adibi P. A Dish-based Semi-quantitative Food Frequency Questionnaire for Assessment of Dietary Intakes in Epidemiologic Studies in Iran: Design and Development. Int J Prev Med 2014; 5(1): 29-36.
  13. Montazeri A, Harirchi AM, Shariati M, Garmaroudi G, Ebadi M, Fateh A. The 12-item General Health Questionnaire (GHQ-12): translation and validation study of the Iranian version. Health Qual Life Outcomes 2003; 1: 66.
  14. Montazeri A, Vahdaninia M, Ebrahimi M, Jarvandi S. The Hospital Anxiety and Depression Scale (HADS): translation and validation study of the Iranian version. Health Qual Life Outcomes 2003; 1: 14.
  15. Ligaarden SC, Lydersen S, Farup PG. Diet in subjects with irritable bowel syndrome: a cross-sectional study in the general population. BMC Gastroenterol 2012; 12: 61.
  16. Bohn L, Storsrud S, Tornblom H, Bengtsson U, Simren M. Self-reported food-related gastrointestinal symptoms in IBS are common and associated with more severe symptoms and reduced quality of life. Am J Gastroenterol 2013; 108(5): 634-41.
  17. Heizer WD, Southern S, McGovern S. The role of diet in symptoms of irritable bowel syndrome in adults: a narrative review. J Am Diet Assoc 2009; 109(7): 1204-14.
  18. Parker TJ, Woolner JT, Prevost AT, Tuffnell Q, Shorthouse M, Hunter JO. Irritable bowel syndrome: is the search for lactose intolerance justified? Eur J Gastroenterol Hepatol 2001; 13(3): 219-25.
  19. Gupta D, Ghoshal UC, Misra A, Misra A, Choudhuri G, Singh K. Lactose intolerance in patients with irritable bowel syndrome from northern India: a case-control study. J Gastroenterol Hepatol 2007; 22(12): 2261-5.
  20. Boirie Y, Dangin M, Gachon P, Vasson MP, Maubois JL, Beaufrere B. Slow and fast dietary proteins differently modulate postprandial protein accretion. Proc Natl Acad Sci USA 1997; 94(26): 14930-5.
  21. Garcia-Talavera Espin NV, Gomez Sanchez MB, Zomeno Ros AI, Nicolas HM, Gonzalez Valverde FM, Gomez Ramos MJ, et al. Comparative study of two enteral feeding formulas in hospitalized elders: casein versus soybean protein. Nutr Hosp 2010; 25(4): 606-12. [In Spanish].
  22. Hassanzadeh A, Esmaillzadeh A, Mirzaei S, Motahari F, Saneei P, Daghaghzadeh H. The association between dairy intake and upper gastrointestinal disorder. J Health Syst Res 2013; Nutrition supplement:1481-90. [In Persian].
  23. Saito YA, Locke GR 3rd, Weaver AL, Zinsmeister AR, Talley NJ. Diet and functional gastrointestinal disorders: a population-based case-control study. Am J Gastroenterol 2005; 100(12): 2743-8.
  24. Bohn L, Storsrud S, Simren M. Nutrient intake in patients with irritable bowel syndrome compared with the general population. Neurogastroenterol Motil 2013; 25(1): 23-30.
  25. Saberi-Firoozi M, Khademolhosseini F, Mehrabani D, Yousefi M, Salehi M, Heidary ST. Subjective lactose intolerance in apparently healthy adults in southern Iran: Is it related to irritable bowel syndrome? Indian J Med Sci 2007; 61(11): 591-7.
Journal of Isfahan Medical School
Volume 34, Issue 400 - Serial Number 400
July and August 2016
Pages 1134-1143

Files

History

  • Receive Date: 02 July 2016
  • Revise Date: 24 May 2024
  • Accept Date: 06 April 2022

Share

How to cite

Statistics