Evaluation of Changes in Blood Factors, Liver Functional Tests, and Thyroid Tests in Radiation Workers in Hospitals in Kurdistan Province, Iran

Document Type : Original Article (s)

Authors

1 Instructor, Department of Radiology, School of Paramedical Sciences, Kurdistan University of Medical Sciences, Sanandaj, Iran

2 Assistant, Department of Medical Physics, School of Medicine, Kurdistan University of Medical Sciences, Sanandaj, Iran

3 MSc in Radiobiology and Radiation Protection, Vice-Chancellor for Food and Drug, Kurdistan University of Medical Sciences, Sanandaj, Iran

4 Instructor, Department of Radiotherapy, School of Paramedical Sciences, Kurdistan University of Medical Sciences, Sanandaj, Iran

5 Assistant Professor, Social Determinants of Health Research Center, Kurdistan University of Medical Sciences, Sanandaj, Iran

Abstract

Background: Using ionizing radiation in diagnosis and treatment is of great importance. As early diagnosis in some diseases only can be done by using radiation, in treatment phase, radiotherapy is also the main center for healing patients with cancer. Today, one of occupational hazards is ionizing radiation which can cause serious and irreparable damages in radiation workers. This study aimed to count blood cells and evaluate liver enzymes and thyroid-stimulating hormone (TSH) in radiation workers in hospitals in Kurdistan Province, Iran.Methods: In this case-control study, blood cells, liver enzymes, and TSH levels were compared in 142 radiation staff (cases) and also 142 workers in other sections of hospitals. Matching was done for confounding factors. The statistical analysis was performed using SPSS software at the significance level of P < 0.05.Findings: Mean number of white blood cells and the level of serum alanine aminotransferase (ALT) enzyme in radiation staff were significantly different from that of the control group. But no significant difference was observed between other parameters.Conclusion: It seems that working in radiation wards can change some blood factors but can not predict the recieved dose. In order to increase the safety of radiation workers in radiation wards, monitoring of these individuals should be done annually using cytogenetic methods.

Keywords

References

  1. Rastikerdar S, Naderi MH. Fundamentals of radiation protection. 1st ed. Isfahan, Iran: University of Isfahan Publications; 2000. [In Persian].
  2. International Atomic Energy Agency. Cytogenetic analysis for radiation dose assessment, technical reports series No. 405. Vienna, Austria: IAEA; 2001.
  3. Feinendegen LE, Pollycove M, Sondhaus CA. Responses to low doses of ionizing radiation in biological systems. Nonlinearity Biol Toxicol Med 2004; 2(3): 143-71.
  4. Maffei F, Angelini S, Forti GC, Lodi V, Violante FS, Mattioli S, et al. Micronuclei frequencies in hospital workers occupationally exposed to low levels of ionizing radiation: influence of smoking status and other factors. Mutagenesis 2002; 17(5): 405-9.
  5. Stamm A, Bogl W, Willich N, Lissner J. Biochemical indicators of radiation exposure, assessment of serum thymidine concentration, serum amylase activity and isoenzyme activities of acid serum phosphatase. Proceedings of the 7th International Congress of Radiation Research; 1983 Jul 3-8; Amsterdam, Netherlands.
  6. Giaccia AJ, Hall EJ. Radiobiology for the radiologist. Philadelphia, PA: Lippincott Williams and Wilkins; 2006.
  7. Shabestani Monfared A, Amiri M, Hashem Oghla S. Chromosomal damages in radiology technicians in Babol. J Mazandaran Univ Med Sci 2006; 16(51): 43-51. [In Persian].
  8. Mozdarani H. Biological dosimetry: Biomarkers and methods. Tehran, Iran: Teb-e Novin Publications; 2004. [In Persian].
  9. Tavakkoli MR, Moradalizade M, Ananisarab GR, Hosseini SM. Evaluation of blood cell count in the radiology staff of Birjand Hospitals in 2011. Modern Care 2012; 9(2): 80-6. [In Persian].
  10. Zargan S, Seyedmehdi S, Emami H, Attarchi M, Yazdanparast T, hamidi H. Comparison of blood cells in radiology workers and non-radiation workers staff of a governmental hospital in Tehran. J Occu Health Epidemiol 2016; 13(4): 31-8. [In Persian].
  11. Khamisipour G, Tamjidi A, Tamjidi A, Nabipour I. Genetic damages in radiation workers of radiology centers in Bushehr port. Iran South Med J 2004; 7 (1): 11-8. [In Persian].
  12. Qian QZ, Cao XK, Liu HY, Shen FH, Wang Q, Tong JW, et al. Analysis of hemogram of radiation workers in Tangshan, China. J Clin Lab Anal 2016; 30(5): 682-8.
  13. Zahedi R, Bakhshandeh M, Sabouri H, Yar Ahmadi M, Nami A, Roshani D. Early effect of radiation on the liver function tests of patients with thoracic and abdominal tumors during radiotherapy. J Paramed Sci 2016; 7(3): 8-12.
  14. Miles DA, Van Dis ML, Razmus TF. Basic principles of oral and maxillofacial radiology. Philadelphia, PA; Saunders; 1992.
Journal of Isfahan Medical School
Volume 35, Issue 453 - Serial Number 453
September and October 2018
Pages 1532-1539

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History

  • Receive Date: 18 September 2017
  • Revise Date: 25 May 2024
  • Accept Date: 06 April 2022

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