Analysis of Traditional Risk Factors on ST-Segment Elevation Myocardial Infarction Characteristics

Document Type : Original Article(s)

Authors

1 Assistant Professor, Interventional Cardiology Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran

2 Assistant Professor, Heart failure research center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran

3 Cardiac Rehabilitation Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran

4 Associated Professor, Heart failure research center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran

5 Hypertension Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran

6 Isfahan Cardiovascular Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran

7 Professor, Cardiac Rehabilitation Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran

Abstract

Background: Acute myocardial infarction (AMI) is one of the major attributes of mortality and morbidity worldwide. The current study aims to assess the association of each risk factor with the characteristics of AMI.
Methods: In this cross-sectional report that was conducted in Chamran, Khurshid, and Faiz hospitals in Isfahan, the relationship between demographic characteristics of patients (age, gender, body mass index, current smoking, diabetes, high blood pressure, and hypercholesterolemia) with clinical and paraclinical parameters of AMI, from Including the extent of AMI, the severity (involvement) of coronary arteries, that involved epicardial coronary artery, and the success rate of PCI were evaluated based on TIMI grading.
Findings: In this study, 478 STEMI patients with a mean age of 60.41 ± 12.79 years and 396 males (82.8%) were included in the study. Smoking is significantly associated with the occurrence of anterior MI; 84% more smoking patients experienced anterior MI compared to non-smoking patients (P = 0.012). The involvement of the left anterior descending (LAD)/diagonal arteries was significantly related to smoking so smokers were 2.34 times more likely to have (P = 0.033). In addition, hypercholesterolemia was inversely related to PCI success (P = 0.006). Patients with a younger age had more PCI success (P = 0.002). Previous TIMI patients with two-vessel involvement have a significant relationship with body mass index (P = 0.024).
Conclusion: According to this study, smoking was an independent predictor for anterior myocardial wall blood supply interruption and anterior wall infarctions. Hypercholesterolemia was inversely associated with post-PCI TIMI flow grade III achievement. Besides, the concurrent presence of three or more comorbidities was associated with the severity of CAD.

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References

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Journal of Isfahan Medical School
Volume 42, Issue 776
4th Week, September
September and October 2024
Pages 624-632

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History

  • Receive Date: 05 March 2023
  • Revise Date: 12 June 2024
  • Accept Date: 22 September 2024

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