Comparing the Effectiveness of Oral Corticosteroids, Pineapple Extract, and Placebo in Treating Ecchymosis and Edema after Rhinoplasty Surgery

Document Type : Original Article (s)

Authors

1 Professor, Department of Otorhinolaryngology, Head and Neck Surgery, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

2 Assistant Professor, Department of Ear, Nose and Throat, Faculty of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

3 Resident, Department of Otorhinolaryngology, Head and Neck Surgery, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

Abstract

Background:  One of the unwanted effects after rhinoplasty surgery is ecchymosis and edema. Considering the importance of the health and satisfaction of patients after rhinoplasty surgery, proper and efficient management is one of the first goals of doctors after surgery. As a result, the purpose of this research is to compare the intensity of the effect of oral corticosteroid and pineapple extract and placebo on the treatment of ecchymosis and edema after rhinoplasty surgery.
Methods: The statistical population includes people who went to Al-Zahra Hospital and Kashani Hospital for rhinoplasty surgery in 2023. Patients were randomly selected from among 60 patients referred for rhinoplasty surgery, who were randomly divided into appropriate groups treated with placebo, oral corticosteroids, and pineapple extract.
Findings: The findings showed that there is no significant difference between the effect of oral corticosteroid and pineapple extract and placebo on the treatment of ecchymosis and edema one day and two weeks after rhinoplasty surgery; However, there is a significant difference between the effect of oral corticosteroid and pineapple extract and placebo on the treatment of ecchymosis and edema one week after rhinoplasty surgery (P < 0.001).
Conclusion: It is concluded that oral corticosteroids are more effective in treating ecchymosis and edema one week after surgery than rhinoplasty surgery. Oral corticosteroids can be used as an effective treatment method. Pineapple extract does not have a significant effect in reducing edema and ecchymosis after surgery, so extra costs can be avoided by preventing the administration of pineapple extract.

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References

  1. Saedi B, Sadeghi M, Fekri K. Comparison of the effect of corticosteroid therapy and decongestant on reducing rhinoplasty edema. Am J Rhinol Allergy 2011; 25(4): e141-4.
  2. Adamson PA, Galli SKD. Rhinoplasty approaches: current state of the art. Arch Facial Plast Surg 2005; 7(1): 32-7.
  3. Johnson CM Jr, Toriumi DM, Daniel RK. Open structure rhinoplasty. Plast Reconstr Surg 1990; 86(3): 594.
  4. Rohrich RJ, Hollier Jr LH, Janis JE, Kim J. Rhinoplasty with advancing age. Plast Reconstr Surg 2004; 114(7): 1936-44.
  5. Bian X, Liu H, Sun J, Zhang X, Li N, Chen M. Efficacy of dexamethasone for reducing edema and ecchymosis after rhinoplasty: a systematic review and meta-analysis. Aesthetic Plast Surg 2020; 44(5): 1672–84.
  6. Kosucu M, Ömür S, Besir A, Uraloglu M, Topbas M, Livaoglu M. Effects of perioperative remifentanil with controlled hypotension on intraoperative bleeding and postoperative edema and ecchymosis in open rhinoplasty. J Craniofac Surg 2014; 25(2): 471–5.
  7. Ong AA, Farhood Z, Kyle AR, Patel KG. Interventions to decrease postoperative edema and ecchymosis after rhinoplasty: a systematic review of the literature. Plast Reconstr Surg 2016; 137(5): 1448–62.
  8. Hashemi M, Mokhtarinezhad F, Omrani M. A comparison between external versus internal lateral osteotomy in rhinoplasty. Journal of Research in Medical Sciences 2005; 1: 10-5.
  9. Gabrick K, Walker M, Timberlake A, Chouairi F, Saberski E, Steinbacher D. The effect of autologous fat grafting on edema and ecchymoses in primary open rhinoplasty. Aesthet Surg J 2020; 40(4): 359–66.
  10. Rahimi Fard M, Mousavi S J, Ghasemi Firouzabadi A, Zarezadeh N. Investigating the effect of phenytoin on reducing the dose of coronet in asthmatic patients [in Persian]. J Shahid Sadoughi Univ Med Sci 2003; 11(3): 22-7.
  11. Gurlek A, Fariz A, Aydogan H, Ersoz-Ozturk A, Eren AT. Effects of different corticosteroids on edema and ecchymosis in open rhinoplasty. Aesthet Surg J 2006; 30(2): 150-4.
  12. Gutierrez S, Wuesthoff C. Testing the effects of long-acting steroids in edema and ecchymosis after closed rhinoplasty. Plast Surg (Oakv) 2014; 22(2): 83–7.
  13. Rohrich RJ, Ahmad J. Rhinoplasty. Plast Reconstr Surg 2011; 128(2): 49e-73e.
  14. Rettinger G. Risks and complications in rhinoplasty. GMS Curr Top Otorhinolaryngol Head Neck Surg 2007; 6: Doc08.
  15. Daniel RK. The preservation rhinoplasty: a new rhinoplasty revolution. Aesthet Surg J 2018; 38(2): 228-9.
  16. Godone RLN, Leitão GM, Araújo NB, Castelletti CHM, Lima-Filho JL, Martins DBG. Clinical and molecular aspects of breast cancer: Targets and therapies. Biomed Pharmacother 2018; 106: 14-34.
  17. DeAngelis LM. Brain tumors. N Engl J Med 2001; 344(2): 114–23.
  18. Ghazipour A, Akbari Dilmaghani N. The effect of dexamethasone on reducing ecchymosis and edema around the eyes after rhinoplasty surgery [in Persian]. Iranian Journal of Otorhinolaryngology 2007; 19(1): 7-10.
  19. Dabirmoghaddam P, Baradaranfar MH, Gouinee F, Ayatallahi V. The effect of intravenous dexamethasone in reducing periorbital edema, ecchymosis and intraoperative bleeding in rhinoplasty patients [in Persian]. Tehran Univ Med J 2007; 65(8): 29-34.
  20. Ghaedi M, Sadeghi E, Sahraeai R, Sanie Jahromi MS, Sohrabpour M, Kalani N. Comparison of intraoperative administration of ketorolac and morphine in postoperative pain control in septorhinoplasty patients: A double-blind randomized clinical trial study [in Persian]. Journal of Iranian Anesthesiology and Intensive Care. 2023; 2(117): 30-37.

 

Journal of Isfahan Medical School
Volume 42, Issue 785
1st Week, December
November and December 2024
Pages 850-856

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History

  • Receive Date: 17 June 2024
  • Accept Date: 07 October 2024

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