Investigating the Effect of Suborbital Launch Conditions of the Biological Capsule on Probiotic Microorganisms

Document Type : Original Article(s)

Authors

1 Assistant Professor, Air and Space Physiology Research Group, Aerospace Research Institute, Ministry of Science, Research and Technology, Tehran, Iran

2 Professor, Research Department of Food Technology Research, National Nutrition and Food Technology Research Institute, Shahid Beheshti University of Medical Sciences, Tehran, Iran

Abstract

Background: According to the reports about the increasing antibiotic resistance and resistance to environmental stresses of microbes in outer space. This research investigates the potential effects of space conditions on the growth rate, survival, and stress resistance of probiotic bacteria native to Iran.
Methods: Probiotics of Lactobacillus (L.) acidophilus, Lactiplantibacillus (L.) plantarum, and Saccharomyces (S.) cerevisiae were launched and recovered in Iran's newest biological capsule named Kavos at a height of 1300 km from the sea level. Growth of microorganisms and resistance to osmotic, acid, and temperature shock, as well as antibiotic resistance, were measured and compared with controls.
Findings: The results showed that the launch stress increased the growth rate and decreased the lag phase duration in lactobacilli. The optimum growth temperature and tolerance against acid shock did not change in probiotics before and after launch. The osmotic shock tolerance in L. plantarum increased significantly in the samples after the launch, but in L. acidophilus and the yeast did not change. Except for the increase in L. acidophilus resistance to gentamicin and amoxicillin and L. plantarum to ampicillin and doxycycline in launch samples, no change was observed in other antibiotics.
Conclusion: The results showed that the probiotic strains are fast-growing and resistant to environmental. Therefore, probiotics consumption can be necessary several times more to maintain the health of space travelers than life on Earth. These probiotics are also recommended to improve the quality of human life on Earth.

Highlights

Maryam Salavatifar: Google Scholar, PubMed

Kianoush Khosravi-Darani: Google Scholar, PubMed

Keywords

Main Subjects

References

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Journal of Isfahan Medical School
Volume 42, Issue 794
2nd Week, February
January and February 2025
Pages 1077-1085

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History

  • Receive Date: 01 June 2024
  • Accept Date: 25 January 2025

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