Investigating the Causes of Abnormal Uterine Bleeding in Endometrial Curettage Samples of Patients in Reproductive and Premenopausal Age at Beheshti Hospital in Isfahan

Document Type : Original Article(s)

Authors

1 Assistant Professor of Pathology, Department of Pathology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

2 Associate Professor of Community Medicine, Department of Community and Family Medicine, School of Medicine, Social Determinants of Health, Isfahan, Iran

3 Department of Pharmacology, School of Medicine, Tehran University of medical sciences, Tehran, Iran

4 School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

10.48305/jims.v43.i828.0997

Abstract

Background: Abnormal Uterine Bleeding (AUB) is regarded as one of the most common complaints in gynecological clinics and can lead to anemia, weakness, general discomfort, and can prevent the person from participating in social activities. Its prevalence increases with age. This study aimed to investigate the causes of AUB based on the International Federation of Gynecology and Obstetrics (FIGO) classification and to compare the frequency of these causes between reproductive-age and premenopausal patient groups based on pathological results.
Methods: In this retrospective study, the records of patients who presented with AUB at Beheshti Hospital, Isfahan University of Medical Sciences, from March 2022 to March 2023 and underwent diagnostic curettage were reviewed. Individuals aged 15-55 years were included. Participants were divided into two groups: reproductive (15-45) and pre-menopausal (46-55).
Findings: In the premenopausal group, the frequency of polyp was 54.76%, adenomyosis 6.36%, leiomyoma 23.02%, malignancies 1.58%, coagulation disorders 0.79%, endometrial disorders 10.32%, unclassified factors 0.79%, and polyp+leiomyoma was 2.38%. In the reproductive group, the frequency of polyp was 57.41%, adenomyosis 0.76%, leiomyoma 30.04%, malignancy 1.52%, coagulation disorders 0.38%, endometrial disorder 7.99%, coagulation disorder + polyp 0.38%, and polyp + leiomyoma 1.52%. The comparison of the age groups showed that the frequency of adenomyosis in both groups was significantly different.
Conclusion: The frequency of polyp, leiomyoma and endometrial disorder ranked first to third, respectively in both age groups and the most common cause of AUB was polyps.

Highlights

Elham Omidi: Google Scholar

Narges Motamedi: Google Scholar

Shiva Ghareghani: Google Scholar, PubMed

Keywords

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References

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Journal of Isfahan Medical School
Volume 43, Issue 828
4th Week, October
September and October 2025
Pages 997-1003

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History

  • Receive Date: 11 February 2025
  • Accept Date: 05 October 2025

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