Determination of Streptococcus Sanguis in Gingivitis Disease and Effect of β-lactam Antibiotics on It

Document Type : Original Article(s)

Authors

1 MSc in Microbiology, Department of Science–Biology, Falavarjan Branch, Islamic Azad University, Isfahan

2 Professor, Department of Basic Sciences–Biology, AlZahra University, Tehran

3 Associate Professor, Department of Oral Diseases, School of Dentistry, Isfahan University of Medical Sciences, Isfahan

4 Pharmaceutics Specialist, Farabi Pharmacy, Isfahan

Abstract

Background: Gingivitis is a destructive inflammatory disease. The results of some studies show that bacteria of plaques are different in diseased and healthy areas; so the identification and sensitivity to β-lactam antibiotics was the most important aim of this study. Methods: This study was performed on 361 strains of bacteria identified by biochemical tests; the number of streptococcus and its percentage were 204 and 55.9 respectively. The antimicrobial susceptibility of strains of streptococcus was determined by Disk plate or Kerby–Bauer. The difference between the mean zones of inhibition of gingivitis strains were studied by t-test. Findings: The percentages of streptococcus sanguis was 26.4% and of streptococcus sanguis more than 70%. These bacteria were sensitive to amoxicillin, co-amoxiclave, and erythromycin and also sensitive to tetracycline, penicillin, and cephalexin. 1% of these bacteria were sensitive to clindamyc. Conclusion: These bacteria were sensitive to β-lactam antibiotics, and we can use β-lactam antibiotics for treatment.

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History

  • Receive Date: 17 February 2011
  • Revise Date: 26 May 2024
  • Accept Date: 06 April 2022

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