Document Type : Review Article
Authors
1
PhD. Candidate, Department of Exercise Physiology, Faculty of Humanities and Social Sciences, University of Kurdistan, Sanandaj, Iran
2
Associate Professor, Department of Exercise Physiology, Faculty of Physical Education and Sports Sciences, Allameh Tabataba'i University, Tehran, Iran
3
PhD Student, Department of Exercise Physiology, Faculty of Humanities and Social Sciences, University of Kurdistan, Sanandaj, Iran
4
MSc, Department of Exercise Physiology, Faculty of Humanities and Social Sciences, University of Kurdistan, Sanandaj, Iran
10.48305/jims.v43.i826.0956
Abstract
Background: The purpose of this systematic review and meta-analysis is to examine the effect of exercise training on adiponectin levels in patients with type 2 diabetes mellitus (T2DM) based on gender.
Methods: This systematic review and meta-analysis were conducted based on the PRISMA guidelines and the Sex and Gender Equity in Research (SAGER). To extract relevant information for the study, reputable databases including PubMed, Web of Science, Scopus, Google Scholar, and the Persian language database (SID) were searched by two independent researchers to find studies that had examined the effect of exercise on adiponectin levels in individuals with T2DM. The combined effects of interventions were assessed as standardized mean differences (SMD) using a random-effects model. Sensitivity analysis was performed to evaluate the influence of specific studies on the overall results.
Findings: According to the findings of this meta-analysis, exercise training had a significant effect on adiponectin levels in women with T2DM (SMD = -0.77, 95% CI: (-0.35 to -1.18), P < 0.01), but no significant effect was observed in the analysis of data related to men with T2DM (SMD = -0.35, 95% CI: -0.06 to -0.77, P = 0.09).
Conclusion: Based on the results of this meta-analysis, exercise training can effectively play a role by controlling plasma levels of adiponectin as a non-pharmacological strategy in improving the complications caused by the disease in women with T2DM.
Highlights
Aref Mehdipour: Google Scholar
Seyed Morteza Tayeby: Google Scholar
Ehsan Amiri: Google Scholar
Keywords
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