The Study of Relationship between Diabetic Retinopathy and Lipid Profile in Type 2 Diabetic Patients

Document Type : Original Article (s)

Authors

1 Assistant Professor, Department of Ophthalmology, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran

2 Assistant Professor, Department of Pathology, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran

Abstract

Background: Type 2 Diabetes is one of the most prevalent diseases of developing societies. Diabetic retinopathy which is considered as a specific complication in type 2 and 1 diabetes, is one of the most complications of diabetes. Blood sugar control and the duration of the illness and lipid profile [total cholesterol (TC), triglyceride (TG), low-density lipoprotein (LDL), high-density lipoprotein (HDL)] are the most important factors in creating diabetic retinopathy. In this study the effect of lipid profile in creating retinopathy was evaluated as aside factors.Methods: The study was performed in the form of analytical-sectional. The society under study in this research includes 300 type 2 diabetic patients who have active cases in the center of diabetes of Hamadan city, Iran, during 2013-2014. The relationship between lipid profile and catching retinopathy were studied in them. The data was analyzed by SPSS software and c2 statistical test.Findings: Altogether 300 patients were studied. 167 people were catching diabetic retinopathy. From 167 people, 34 people suffer from diabetes less than 10 years and 133 people catching diabetes more than 10 years. The statistical analysis done on the similar people regarding to the duration of diabetes didn’t show any significant relationship between lipid profile and catching retinopathy in type 2 diabetic patients and its acuteness.Conclusion: Based on findings, lipid profile in type 2 diabetic patients didn’t show any significant relationship with catching retinopathy and its acuteness.

Keywords

References

  1. Saikumar S, Giridhar A, Mahesh G, Elias A, Bhat S. Awareness about eye diseases among diabetic patients: a survey in South India. Community Eye Health 2007; 20(61): 16-7.
  2. Real JT, Valls M, Ascaso P, Basanta ML, Viguer AA, Ascaso JF, et al. Risk factors associated to hospitalization in diabetic patients with foot ulcers. Med Clin (Barc ) 2001; 117(17): 641-4. [In Spanish].
  3. Stratton IM, Kohner EM, Aldington SJ, Turner RC, Holman RR, Manley SE, et al. UKPDS 50: risk factors for incidence and progression of retinopathy in Type II diabetes over 6 years from diagnosis. Diabetologia 2001; 44(2): 156-63.
  4. Shoja MR, Mahdavi M, Manaviat MR, Besharati MR. Serum lipids and various degrees of diabetic retinopathy. Tehran Univ Med J 2007; 64(11): 57-64. [In Persian].
  5. Rama Krishna K. A one year cross sectional study to determine the relationship between serum lipid profile and diabetic retinopathy [Doctoral Thesis]. Belgaum, India: Jawaharlal Nehru Medical College; 2009.
  6. Mathur A, Mathur R. Study of association of serum lipids with diabetic retinopathy in type 2 diabetes mellitus. People's Journal of Scientific Research 2013; 6(1): 94-7.
  7. Rianita R, Bardosono S, Victor AA. Relationship between plasma lipid profile and the severity of diabetic retinopathy in type 2 diabetes patients. Med J Indones 2008; 17(4): 221-5.
  8. Fauci AS, Braunwald E, Kasper DL, Hauser SL, Longo DL, Jameson DL, et al. Harrison's Principles of Internal Medicine. 17th ed. New York, NY: McGraw-Hill; 2008. p. 1859.
  9. Cetin EN, Bulgu Y, Ozdemir S, Topsakal S, Akin F, Aybek H, et al. Association of serum lipid levels with diabetic retinopathy. Int J Ophthalmol 2013; 6(3): 346-9.
  10. Jayalakshmi V, Satya Narayana K, Sravanthi K, Ivvala AS. The evaluation of serum fasting blood sugar and lipid profile including Apo A and Apo B in diabetic retinopathy subjects. Indian Journal of Basic and Applied Medical 2012; 1(2): 94-102.
Journal of Isfahan Medical School
Volume 34, Issue 380 - Serial Number 380
March and April 2016
Pages 444-449

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History

  • Receive Date: 22 April 2016
  • Revise Date: 27 May 2024
  • Accept Date: 06 April 2022

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