Journal of Isfahan Medical School

Journal of Isfahan Medical School

The Relative Frequency of Depression and Anxiety in Patients with Hepatitis B Referring to Infectious Diseases and Tropical Medicine Research Center, Isfahan, Iran

Document Type : Original Article (s)

Authors
Behrooz Ataei 1
Farzin Khorvash 1
Mehrdad Salehi 2
Sarah Houshmand 3
Nazila Kassaian 4
Anahita Babak 5
Zari Nokhodian 4
Mehdi Ataei 6
1 Associate Professor, Department of Infectious Diseases, School of Medicine And Infectious Diseases and Tropical Medicine Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
2 Associate Professor, Behavioral Sciences Research Center, Department of Psychiatry, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
3 Student of Medicine, Student Research Committee, Isfahan University of Medical Sciences, Isfahan, Iran
4 Researcher, Infectious Diseases and Tropical Medicine Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
5 Specialist in Community Medicine, Infectious Diseases and Tropical Medicine Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
6 Student of Medicine, Najaf Abad Branch, Islamic Azad University, Isfahan, Iran
Abstract
Background: Hepatitis B is one of the common liver diseases. It also affects mental and social aspects of life.Methods: In this cross- sectional study, patients affected with chronic hepatitis B who referred to Infectious Diseases and Tropical Medicine Research Center, Isfahan, Iran were studied. After filling a validated questionnaire including demographics and information related to depression and anxiety, the data was analyzed.Findings: Among 107 patients with chronic hepatitis B (78 males and 29 females with mean age of 39 ± 13 years), none had depression and only 2.8% suffered from anxiety.Conclusion: This study demonstrated that patients with chronic hepatitis B do not have depression. One of the causes might be inadequate information about the disease. Such lack of information needs to be taken care of by physicians and authorities. 
Keywords
Hepatitis B
Depression
Anxiety
  1. Ebrahimi Daryani N, Bashashati M, Karbalaeian M, Keramati MR, Ebrahimi Daryani N, Shadman Yazdi AA. Prevalence of disorders in hepatitis B Virus carriers in Iranian charity for hepatic patients support. Hepatitis Monthly 2008; 8(3): 201-5.
  2. Fauci A, Braunwald E, kasper D, Hauser S, Longo D, Jameson J, et al. Harrison's Principles of Internal Medicine. 17th ed. New York: Mc Graw-Hill; 2008.
  3. Alavian SM, Fallahian F, Lankarani KB. The changing epidemiology of viral hepatitis B in Iran. J Gastrointestin Liver Dis 2007; 16(4): 403-6.
  4. Alavian SM, Tavallaii SA, Hoseini SM, Hedayati MR, Sepehrinia A. Prevalence of depression in chronic Hepatitis B and C patients treated with Interferon. Kowsar Medical Journal 2007; 12(2): 161-7.
  5. Ong SC, Mak B, Aung MO, Li SC, Lim SG. Health-related quality of life in chronic hepatitis B patients. Hepatology 2008; 47(4): 1108-17.
  6. Atesci FC, Cetin BC, Oguzhanoglu NK, Karadag F, Turgut H. Psychiatric disorders and functioning in hepatitis B virus carriers. Psychosomatics 2005; 46(2): 142-7.
  7. Altindag A, Cadirci D, Sirmatel F. Depression and health related quality of life in non-cirrhotic chronic hepatitis B patients and hepatitis B carriers. Neurosciences (Riyadh) 2009; 14(1): 56-9.
  8. Weinstein AA, Kallman PJ, Stepanova M, Poms LW, Fang Y, Moon J, et al. Depression in patients with nonalcoholic fatty liver disease and chronic viral hepatitis B and C. Psychosomatics 2011; 52(2): 127-32.
  9. Karaivazoglou K, Iconomou G, Triantos C, Hyphantis T, Thomopoulos K, Lagadinou M, et al. Fatigue and depressive symptoms associated with chronic viral hepatitis patients. health-related quality of life (HRQOL). Ann Hepatol 2010; 9(4): 419-27.
  10. Steel J, Carney M, Carr BI, Baum A. The role of psychosocial factors in the progression of hepatocellular carcinoma. Med Hypotheses 2004; 62(1): 86-94.
  11. Sadock BJ, Sadock VA. Kaplan and Sadock's Concise Textbook of Clinical Psychiatry. 3rd ed. Philadelphia: Lippincott Williams & Wilkins; 2008.
  12. Alavaian SM, Tavallaii SA, Aziz Abadi Farahani M, Khoddami-Vishteh HR, Bagheri Lankarani K. Evaluation of the severity of depression and anxiety in hepatitis B and hepatitis C patients: a case control study. Iranian Journal of Clinical Infectious Disease 2007; 2(3): 113-9.
  13. Shi XH, Xun J, Wang SP, Zhang J. Study on depression in 212 patients with viral hepatitis. Zhonghua Liu Xing Bing Xue Za Zhi 2009; 30(10): 1060-4.
  14. Beck AT. Beck Depression Inventory: Manual. San Antonion: The Psychological Corporation; 1996.
  15. Zung WW. A rating instrument for anxiety disorders. Psychosomatics 1971; 12(6): 371-9.
  16. Scheft H, Fontenette DC. Psychiatric barriers to readiness for treatment for hepatitis C Virus (HCV) infection among injection drug users: clinical experience of an addiction psychiatrist in the HIV-HCV coinfection clinic of a public health hospital. Clin Infect Dis 2005; 40(Suppl 5): S292-S296.
  17. Ataei B, Babak A, Yaran M, Kassaian N, Nokhodian Z, Meshkati M, et al. Hepatitis C in intravenous drug users: seroprevalence and risk factors. Journal of Isfahan Medical School 2012; 28(Special): 1537-45.
  18. Batki SL, Canfield KM, Smyth E, Ploutz-Snyder R. Health-related quality of life in methadone maintenance patients with untreated hepatitis C virus infection. Drug Alcohol Depend 2009; 101(3): 176-82.
  19. Ren XS, Amick B, III, Zhou L, Gandek B. Translation and psychometric evaluation of a Chinese version of the SF-36 Health Survey in the United States. J Clin Epidemiol 1998; 51(11): 1129-38.
  20. Niederau C, Fischer C, Kautz A. Socio-economical aspects, quality of life and state of knowledge in hepatitis B patients. Socio-economical aspects in hepatitis B. Z Gastroenterol 2007; 45(5): 355-68.
Journal of Isfahan Medical School
Volume 29, Issue 169 - Serial Number 169
November and December 2012
Pages 2599-2604

  • Receive Date 31 October 2011
  • Accept Date 06 April 2022