1
Associate Professor, Department of Infectious Diseases, School of Medicine AND Infectious Diseases and Tropical Medicine Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
2
Student of Medicine, School of Medicine AND Student Research Committee, Isfahan University of Medical Sciences, Isfahan, Iran
Abstract
Background: Some studies suggest that besides the known effects of vitamin D on calcium hemostasis and bone safety, it might also play a non-classic role in our body such as in chronic hepatic disorders. So, considering the high prevalence of vitamin D deficiency and HCV in our society, the aim of this study was to evaluate serum levels of vitamin D in HCV patients compared to a control group.Methods: In this case-control study, 60 HCV patients and 60 healthy pupils were selected and serum level of vitamin D was measured and compared between the two groups.Findings: The mean serum level of Vitamin D in the case and control group was 26.23 ± 18.53 and 29.6 ± 13.61, respectively and no statistical difference was reported between the two groups (P = 0.260). Vitamin D insufficiency was found in 3 patients (5.0%) in the case group and none of the control group. Vitamin D deficiency was found in 43(71.7%) of the case group but only 6 (10.0%) of the control group and this difference between the two group was statistically significant (P = 0.033).Conclusion: According to the results of this study, vitamin D deficiency in HCV patients was higher than the normal population and high prevalence of vitamin D deficiency can affect other organs and decrease the quality of HCV treatment. Thus, measuring the serum levels of vitamin D in HCV patients and prescribing vitamin D supplements are recommended.
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Ataei,B. , Akhavan-Ghorbani,Z. , Khorvash,F. and Ataei,A. (2016). Serum Levels of 25-Hydroxy Vitamin D in Patients with Hepatitis C Compared with Control Group. Journal of Isfahan Medical School, 34(370), 49-55.
MLA
Ataei,B. , , Akhavan-Ghorbani,Z. , , Khorvash,F. , and Ataei,A. . "Serum Levels of 25-Hydroxy Vitamin D in Patients with Hepatitis C Compared with Control Group", Journal of Isfahan Medical School, 34, 370, 2016, 49-55.
HARVARD
Ataei B., Akhavan-Ghorbani Z., Khorvash F., Ataei A. (2016). 'Serum Levels of 25-Hydroxy Vitamin D in Patients with Hepatitis C Compared with Control Group', Journal of Isfahan Medical School, 34(370), pp. 49-55.
CHICAGO
B. Ataei, Z. Akhavan-Ghorbani, F. Khorvash and A. Ataei, "Serum Levels of 25-Hydroxy Vitamin D in Patients with Hepatitis C Compared with Control Group," Journal of Isfahan Medical School, 34 370 (2016): 49-55,
VANCOUVER
Ataei B., Akhavan-Ghorbani Z., Khorvash F., Ataei A. Serum Levels of 25-Hydroxy Vitamin D in Patients with Hepatitis C Compared with Control Group. JIMS, 2016; 34(370): 49-55.
